Current Topics in Medicinal Chemistry


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX

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Most Cited Article

Biological Signatures of Alzheimer’s Disease promotion: free to download

Volume:20   Issue:9
Pp: 770-781
Poornima Sharma, Anjali Sharma, Faizana Fayaz, Sharad Wakode* and Faheem H. Pottoo
DOI: 10.2174/1568026620666200228095553

Coronavirus Disease COVID-19: A New Threat to Public Health promotion: free to download

Volume:20   Issue:8
Pp: 599-600
Sumit Kumar, Poonam and Brijesh Rathi
DOI: 10.2174/1568026620999200305144319

Emerging Proof of Protein Misfolding and Interactions in Multifactorial Alzheimer's Disease promotion: free to download

Volume:20   Issue:26
Pp: 2380-2390
Md. Sahab Uddin*, Abdullah Al Mamun, Md. Ataur Rahman, Tapan Behl, Asma Perveen, Abdul Hafeez, May N. Bin-Jumah, Mohamed M. Abdel-Daim and Ghulam Md Ashraf*
DOI: 10.2174/1568026620666200601161703

Emerging Promise of Immunotherapy for Alzheimer’s Disease: A New Hope for the Development of Alzheimer’s Vaccine promotion: free to download

Volume:20   Issue:13
Pp: 1214-1234
Md. Tanvir Kabir, Md. Sahab Uddin*, Bijo Mathew, Pankoj Kumar Das, Asma Perveen and Ghulam Md. Ashraf*
DOI: 10.2174/1568026620666200422105156

Gut Dysbiosis Dysregulates Central and Systemic Homeostasis via Suboptimal Mitochondrial Function: Assessment, Treatment and Classification Implications promotion: free to download

Volume:20   Issue:7
Pp: 524-539
George Anderson* and Michael Maes
DOI: 10.2174/1568026620666200131094445

Effective Chemicals against Novel Coronavirus (COVID-19) in China promotion: free to download

Volume:20   Issue:8
Pp: 603-605
Wei Liu, Hai-liang Zhu* and Yongtao Duan*
DOI: 10.2174/1568026620999200305145032

Novel Drugs Targeting the SARS-CoV-2/COVID-19 Machinery promotion: free to download

Volume:20   Issue:16
Pp: 1423-1433
Ariane Sternberg, Dwight L. McKee and Cord Naujokat*
DOI: 10.2174/1568026620999200517043137

An Update on Glutamatergic System in Suicidal Depression and on the Role of Esketamine

Volume:20   Issue:7
Pp: 554-584
Domenico De Berardis*, Carmine Tomasetti, Maurizio Pompili, Gianluca Serafini, Federica Vellante, Michele Fornaro, Alessandro Valchera, Giampaolo Perna, Umberto Volpe, Giovanni Martinotti, Silvia Fraticelli, Massimo Di Giannantonio, Yong-Ku Kim and Laura Orsolini
DOI: 10.2174/1568026620666200131100316

Exploring the Potential of Neuroproteomics in Alzheimer's Disease promotion: free to download

Volume:20   Issue:25
Pp: 2263-2278
Md. Sahab Uddin*, Md. Tanvir Kabir, Md. Jakaria, Eduardo Sobarzo-Sánchez, George E. Barreto, Asma Perveen, Abdul Hafeez, May N. Bin-Jumah, Mohamed M. Abdel-Daim and Ghulam M. Ashraf*
DOI: 10.2174/1568026620666200603112030

Construction of a Neuro-Immune-Cognitive Pathway-Phenotype Underpinning the Phenome of Deficit Schizophrenia

Volume:20   Issue:9
Pp: 747-758
Hussein K. Al-Hakeim, Abbas F. Almulla, Arafat H. Al-Dujaili and Michael Maes*
DOI: 10.2174/1568026620666200128143948

Telomerase-based Cancer Therapeutics: A Review on their Clinical Trials

Volume:20   Issue:6
Pp: 433-457
Nicola Relitti*, Akella P. Saraswati, Stefano Federico, Tuhina Khan, Margherita Brindisi, Daniela Zisterer, Simone Brogi, Sandra Gemma, Stefania Butini and Giuseppe Campiani*
DOI: 10.2174/1568026620666200102104930

Evidence Linking Protein Misfolding to Quality Control in Progressive Neurodegenerative Diseases

Volume:20   Issue:23
Pp: 2025-2043
Md. Tanvir Kabir, Md. Sahab Uddin*, Ahmed Abdeen, Ghulam Md Ashraf, Asma Perveen, Abdul Hafeez, May N. Bin-Jumah and Mohamed M. Abdel-Daim
DOI: 10.2174/1568026620666200618114924

Telomere-related Markers for Cancer open access plus

Volume:20   Issue:6
Pp: 410-432
Xiaotian Yuan*, Mingkai Dai and Dawei Xu*
DOI: 10.2174/1568026620666200106145340

Peptide Receptor Radionuclide Therapy: Looking Back, Looking Forward open access plus

Volume:20   Issue:32
Pp: 2959-2969
Danny Feijtel, Marion de Jong and Julie Nonnekens*
DOI: 10.2174/1568026620666200226104652

Periodontal Pathogens and Neuropsychiatric Health

Volume:20   Issue:15
Pp: 1353-1397
Abhishek Wadhawan, Mark A. Reynolds, Hina Makkar, Alison J. Scott, Eileen Potocki, Andrew J. Hoisington, Lisa A. Brenner, Aline Dagdag, Christopher A. Lowry, Yogesh Dwivedi and Teodor T. Postolache*
DOI: 10.2174/1568026620666200110161105

Mathematical Modeling to Address Challenges in Pancreatic Cancer

Volume:20   Issue:5
Pp: 367-376
Prashant Dogra, Javier R. Ramírez, María J. Peláez, Zhihui Wang, Vittorio Cristini, Gulshan Parasher and Manmeet Rawat*
DOI: 10.2174/1568026620666200101095641

Spiro-Lactams as Novel Antimicrobial Agents

Volume:20   Issue:2
Pp: 140-152
Américo J.S. Alves, Nuno G. Alves, Cátia C. Caratão, Margarida I.M. Esteves, Diana Fontinha, Inês Bártolo, Maria I.L. Soares, Susana M.M. Lopes, Miguel Prudêncio, Nuno Taveira and Teresa M.V.D. Pinho e Melo*
DOI: 10.2174/1568026619666191105110049

Mechanisms and Characteristics of Sulfonylureas and Glinides

Volume:20   Issue:1
Pp: 37-56
Wei Lv, Xianqing Wang, Qian Xu and Wencong Lu*
DOI: 10.2174/1568026620666191224141617

Progress in Target Drug Molecules for Alzheimer's Disease

Volume:20   Issue:1
Pp: 4-36
Jiayang Xie, Ruirui Liang, Yajiang Wang, Junyi Huang*, Xin Cao* and Bing Niu*
DOI: 10.2174/1568026619666191203113745

Role of Flavonoids in Neurodegenerative Diseases: Limitations and Future Perspectives

Volume:20   Issue:13
Pp: 1169-1194
Gagandeep Maan, Biplab Sikdar, Ashish Kumar, Rahul Shukla and Awanish Mishra*
DOI: 10.2174/1568026620666200416085330

Isoform-Selective PI3K Inhibitors for Various Diseases

Volume:20   Issue:12
Pp: 1074-1092
Rammohan R.Y. Bheemanaboina*
DOI: 10.2174/1568026620666200106141717

Rosmarinic Acid as a Potent Influenza Neuraminidase Inhibitor: In Vitro and In Silico Study

Volume:20   Issue:23
Pp: 2046-2055
Panupong Mahalapbutr, Mattanun Sangkhawasi, Jirayu Kammarabutr, Supakarn Chamni* and Thanyada Rungrotmongkol*
DOI: 10.2174/1568026619666191118110155