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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Organodilithium Intermediates as Useful Dianionic Synthons: Recent Advances

Author(s): F. Foubelo and M. Yus

Volume 9, Issue 5, 2005

Page: [459 - 490] Pages: 32

DOI: 10.2174/1385272053174921

Price: $65

Abstract

This review will update the use of organodilithium intermediates in synthetic organic chemistry, paying special attention to their use in carbon-carbon bond forming reactions, in which two equal or different electrophiles are introduced (at once or in a two-step process) in the structure of the starting material. This methodology allows the generation of polyfunctionalized organic molecules in a very direct manner through only one synthetic operation: tandem lithiation-reaction with electrophiles.

Keywords: electrophiles, deprotonation, transmetallation reactions, geometries, x-ray diffraction


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