Current Pharmaceutical Analysis

Determination of Acotiamide in Human Plasma by LC-MS/MS and its Application to a Pharmacokinetic Study

Volume:17
Qian Sun, Qiao-gen Zou*, Yun-yan Xia and Cheng-qun Han

Development and Validation of Teneligliptin Stereoisomers by HPLC Using Cellulose Based Immobilized Polysaccharide Chiral Stationary Phase

Volume:17
Gunnam Srinivasu*, Ch Thirupathia, Ch Lakshmi Narayanaa, Ch Parameswara Murthy and Sarah Imam Siddiqui

Detection of diuretic doping by capillary electrophoresis and electrochemical technology: a mini-review

Volume:17
Ping Nan*

A quantitative LC-MS/MS Method for the Simultaneous Determination of the Presence of R-α-lipoic acid and S-α-lipoic acid after Protein Precipitation in rat Plasma and its Application in a Toxicokinetic Study

Volume:17
Wenjun Zhou, Hongqun Qiao*, Lingling Xu, Yanjuan Yuan and Qing Shao

Advances in the use of Graphene Nanocomposites for the Electrochemical Determination of Glucose: A Review

Volume:17
Qinwei Zhou, Boyuan Fan, Jiangwei Zhu, Liqing Fu and Weihong Wu*

A Validated 2D-LC-UV Method for Simultaneous Determination of Imatinib and N-desmethylimatinib in Plasma and Its Clinical Application for Therapeutic Drug Monitoring with GIST Patients

Volume:17
Houli Li, Di Zhang, Xiaoliang Cheng, Qiaowei Zheng, Kai Cheng, Lilong Xiong, Maoyi Wang, Weihua Dong and Weiyi Feng*

Stability Indicating Method for Known and Unknown Impurities Profiling for Vildagliptin in Vildagliptin Tablet

Volume:17
Nitin Mahajan*, Mazhar Farooqui and Suparna Deshmukh

Therapeutic Monitoring of Plasma Digoxin for COVID-19 Patients Using a Simple UPLC-MS/MS Method

Volume:17
Yaru Xing, Lin Yin, Mingquan Guo, Huichun Shi, Tangkai Qi, Lin Wang, Ziqing Kong, Yingying Li, Pengyun Liu, Hongzhou Lu* and Lijun Zhang*

Development, Validation, and Application of a High-Performance Liquid Chromatography Method for the Analysis of Dissolution Samples of Telmisartan and Rosuvastatin Calcium Double-Layer Formulation

Volume:17
Sang-Ho Lee, Sang-Ho Lee, Jong-Hyuk Lee and Joo-Eun Kim*

Q-TOF LC/MS-based Untargeted Metabolomics Approach to Evaluate the Effect of Folate-Conjugated Cyclodextrins on Triple-Negative Breast Cancer Cells

Volume:17
Işıl Varol, Ozan Kaplan, Nazlı Erdoğar, Selin Öncül, Thorbjorn Terndrup Nielsen, Ayşe Ercan, Erem Bilensoy and Mustafa Çelebier*

Ionic Liquids, Microextraction Methods and Capillary Electrophoresis in Biomedical Research

Volume:17
Natalia Miękus*, Martyna Ceraficka, Marta Chyła, Aleksandra Durska and Tomasz Bączek

Development and Validation of an HPLC Method for Five Gliptins in Pharmaceutical Dosage Forms in Finished Marketed Products

Volume:17
Zainab Alkather, Mohammad Hailat, Ramadan Al-Shdefat and Wael Abu Dayyih*

Characterization of a New Impurity in Metaraminol Bitartrate for Injection by 2D HPLC-Q/TOF-MS, Chemical Synthesis and NMR

Volume:17
Wenyan Luo, Hanzhi Zhang*, Ning Sun, Feng Qin and Hao Liu*

Chiral Resolution and Content Determination of Ketorolac Tromethamine Using High-performance Liquid Chromatography

Volume:17
Lei Zheng*, Jing Yang, Yu-yao Guan, Lei Zhang, Chao Song and Xiao-li Zhang

Recent Developments in the Electrochemical Determination of Sulfonamides

Volume:17
Li Fu*, Xinyi Zhang, Su Ding, Fei Chen, Yanfei Lv, Huaiwei Zhang and Shichao Zhao

Development and Validation of a Reliable LC-MS/MS Method for Simultaneous Quantification of Hydrochlorothiazide in Presence of Different co-formulated Anti-hypertensive Medications in Biological Matrix

Volume:17
Heba M. Mohamed* and Yasmin M. Fayez

Investigation and Analytical Applications of the Reaction of N1-methylnicotinamide and Active Methylene Containing Drugs

Volume:17
Heba A. Elsebaie, Mervat H. Elhamamsy, Khaled M. Elokely* and Mohammed A. Eldawy

LC-UV Method for the Estimation of Drug Release from Carvacrol Loaded Nanobeads optimized by Response Surface Methodology

Volume:17
Pinal Talpada and Falguni Tandel*

Metabolic Analysis of Triptolide Microspheres in Human, Dog, Rabbit and Rat Liver Microsomes with UPLC-MS/MS Method

Volume:17
LiJuan Wang*, Yan Liu, Rui Li and DongXian He

Azithromycin Nanosuspension Preparation using Evaporative Precipitation into the Aqueous Solution (EPAS) Method and its Comparative Dissolution Study

Volume:17
Mohammad Hossain Shariare, Tonmoy Kumar Mondal, Hani Alothaid, Md. Didaruzzaman Sohel, MD Wadud, Mohammed S Aldughaim, Md Abdur Rashid and Mohsin Kazi*

Determination of Pharmaceuticals by UV-Visible Spectrophotometry

Volume:17
Avvaru Praveen Kumar* and Deepak Kumar

Development and Validation of an HPLC Method for the Quantification of Morin Flavonoid Encapsulated within PLGA Nanoparticles

Volume:16
Mario Alonso, Emilia Barcia*, Manuel Córdoba-Díaz, Sofia Negro, Damián Córdoba-Díaz and Ana Fernández-Carballido

A Novel GLP-1R/fHCS Method to Determine the Bioactivity of Glucagon-- Like Peptide 1(GLP-1) Analogous Drugs In Vitro

Volume:16
Jie Wang, Ping Lu, Shengting Zhang, Wanwan Li, Xiuling Ji, Jing Li, Hui Zhang, Yunlin Wei* and Chenggang Liang*

A Review on Different Analytical Techniques for Determination of DNP Drugs and their Metabolites in Pharmaceutical Formulations

Volume:16
Puja Bag and Bhupinder Kumar*

Identification of HDACs Inhibitor E14 Metabolites Appeared in Rat Plasma, Feces and Urine by UPLC-QTOF-MS/MS

Volume:16
Juqin Yang, Zhuang Yang, Minghai Tang*, Haoyu Ye and Li Wan

Method, Development, and Validation for the Determination of Residual Solvents in Racecadotril by Gas Chromatography

Volume:16
Sirisha Reddy Sattinena, Alex Joseph*, Subham Das, B Chaitainya and Subba Rao

A Review of the Characteristics, Properties and Methods for Quantification of Roxithromycin

Volume:16
Marcus Vinicius Martins Rubatino, Ana Laura Araújo Santos, Rayssa Araújo dos Santos and Magali Benjamim de Araújo*

Determination of Epsilon Aminocaproic Acid Based on Charge Transfer Complexation with p-Nitrophenlol by Spectrophotometry

Volume:16
Fang Tian and Sheng-Yun Li*

Ultrafiltration-based Sample Preparation for Pharmaceutical Analysis

Volume:16
Mustafa Çelebier*

A Validated Non-compendial Method for Determination of Haemodialysis Concentrate’s Contents and its Comparison with Compendial Method: Application of ISO 13958:2014 Standard

Volume:16
Mahmood Ahmed*, Saghir Ahmad, Riaz Hussain , Anum Khaleeq and Iram Khan

Integrated Quality by Design (QbD) Approach for Stability Indicating RPHPLC Method for the Estimation of Tadalafil Hydrochloride in Bulk Drug and Pharmaceutical Formulations

Volume:16
Prajakta H Patil*, B.M. Gurupadayya and P.D. Hamrapurkar

Elaboration and Validation of HPLC/DAD Method for Quality Control of Products Containing Cannabidiol

Volume:16
Lily Andonova*, Ervin Ivanov, Ivanka Pencheva and Spiro Konstantinov

Systematical Characterization of Impurity Profiles in Daptomycin Raw Material by 2-Dimentional HPLC Tandem with MS Detector

Volume:16
Jin Li, Shang-Chen Yao, Li-Hui Yin, Chang-Qin Hu and Ming-Zhe Xu *

Voltammetric Determination of Diazepam on Antimony Film Screen- Printed Electrode in Pharmaceutical Formulations

Volume:16
Vesna Antunović, Rada Baošić and Aleksandar Lolić*

Application of Chemometrics-assisted HPLC-DAD Strategies for Simultaneous Determination of Paracetamol, Pseudoephedrine HCl, Dextromethorphan HBr, Doxylamine Succinate and Saccharin in Syrup Formulation

Volume:16
Şule Dinç-Zor, Özlem Aksu Dönmez* and Abdürrezzak E. Bozdoğana

Eco-friendly Spectrophotometric Methods for Assessment of Alfuzosin and Solifenacin in their new Pharmaceutical Formulation; Green Profile Evaluation via Eco-scale and GAPI Tools

Volume:16
Mahmoud A. Tantawy, Soheir A. Weshahy, Mina Wadie* and Mamdouh R. Rezk

Diagnosis Model of Hydrogen Sulfide Poisoning Based on Support Vector Machine

Volume:16
Yifan Ying, Yongxi Jin, Xianchuan Wang, Jianshe Ma, Min Zeng* and Xianqin Wang*

Rapid Evaluation Method for Propofol Abusing with Hair by Using Centrifugal Filter and Liquid Chromatography-tandem Mass Spectrometry

Volume:16
Jaesung Pyo*

Preconcentration and Determination of Clomiphene Citrate using Hollow- Fiber Liquid-phase Extraction Coupled with HPLC-UV Detection

Volume:16
Mehdi Ziyarati, Mahnaz Qomi* and Mohammad Yousefi

UPLC-MS/MS Determination of Chlorogenic Acid, Hyperoside and Astragalin in Plasma and its Pharmacokinetic Application in Liver Injury Rats

Volume:16
Ying Zhang, Shu-ya Xu, Zhe Jia, Ting Han, Meng-nan Liu, Tian-ying Jia, Wen-jia Qu, Xinfang Xu and Xiang-ri Li*

Simultaneous Determination of D-amino Acids in Rat Urine by Highperformance Liquid Chromatography-tandem Mass Spectrometry Method: Application to Investigate the Clinical Value of D-amino Acids in the Early Diagnosis of Alzheimer’s Disease

Volume:16
Min Zhang, Shuting Zhang, Weichao Yu, Xiaoyan Li, Ning Ma and Yan Cui*

Metallic Impurities in Pharmaceuticals: An Overview

Volume:16
Poonam Kushwaha *

Metabolic Changes in Mouse Plasma after Acute Diquat Poisoning by UPLC-MS/MS

Volume:16
Lianguo Chen, Zuoquan Zhong, Jiawen Liu, Congcong Wen, Yongxi Jin and Xianqin Wang*

Development and Validation of a Simple HPLC-UV Method to Assay DEET Repellents and its Application to Different Commercial Forms

Volume:16
Juliana dos Santosa, Rebeca Lino Lourenço, Priscila Rosa and Andréa Inês Horn Adams*

Development and Validation of a Method for Simultaneous Estimation of Sitagliptin and Ertugliflozin in Rat Plasma by LC–MS method

Volume:16
P. Venkateswara Rao*, A. Lakshmana Rao and S.V.U.M. Prasad

Analytical Methods Practiced to Quantitation of Rifampicin: A Captious Survey

Volume:16
Rajendra Muljibhai Kotadiya* and Foram Narottambhai Patel

A New Stability-indicating Chiral RP-HPLC Method for the Determination of Degradation Products in Meclizine Hydrochloride

Volume:16
Bryan Gowramma*, Ramachandran Senthil Kumar, Kaviarasan Lakshmanan, Rajagopal Kalirajan and Subramanian Nainar Meyyanathan

Determination of three Unsaturated Fatty Acids in Pressure Ulcer Rats Using a UPLC-MS/MS Method

Volume:16
Fuman Cai, Yuwei Dong, Shaosheng Lou, Zeping Ma, Ting Wu, Liuqing Yang, Congcong Wen* and Chenxiang Wang

A Rapid Method for the Determination of Buprenorphine and Norbuprenorphine in Urine by UPLC-MS/MS

Volume:16
Aykut Kul*, Murat Ozdemir, Selma Ozilhan and Olcay Sagirli

Sustainable Pharmaceutical Preparation Methods and Solid-state analysis Supporting Green Pharmacy

Volume:16
Ilma Nugrahani*

Content and Composition of Phospholipids, Fatty Acids and Sterols in Commercial Natural Phospholipid Excipients

Volume:16
Luxia Zheng*, Xiong Shen, Yingchun Wang, Jian Liang, Mingming Xu, Xinxin Fang, Gang Chen and Guilliang Chen

Characterization of an Unknown Impurity in Indobufen Tablets by HPLC-Q-TOF MS and NMR

Volume:16
Yu Li, Xiangwen Kong, Liya Hong, Chen Yue, Xinyue Wang and Peixi Zhu*

Smart Multivariate Spectrophotometric Assisted Techniques for Simultaneous Determination of Ephedrine Hydrochloride and Naphazoline Nitrate in the Presence of Interfering Parabens

Volume:16
Basma M. Eltanany, Aya A. Mouhamed*, Nesrine T. Lamie and Nadia M. Mostafa

Bioanalytical Method Validation of an RP-HPLC Method for Determination of Rifampicin in Liver Perfusion Studies

Volume:16
Nihan Izat, Ozan Kaplan, Mustafa Celebier and Selma Sahin*

Determination of Free Amino Acids in Banlangen Granule and its Fractions by Solid Phase Extraction Combined with Ion-pair High Performance Liquid Chromatography using a Corona-charged Aerosol Detector (SPE-HPLC-CAD)

Volume:16
Xiuyu Qian*, Lixing Nie, Zhong Dai and Shuangcheng Ma

In Vitro Kinetic Hydrolysis Study of Metronidazole Derivatives with Carvacrol and Eugenol Using Validated RP-HPLC Method

Volume:16
M. Alarjah*

Evaluating Pharmacokinetic and Distribution Characteristics for A New Antitumor Activity Ortho-aryl Chalcone Compound of OC26 in Rats by LC-MS/MS Method

Volume:16
Lexing Chen*, Shiying Li, Jiang Liu, Xia Gan, Zhounan Jiang, Jun Xu and Shaohui Cai

Development of Reverse Phase Ultra-fast Liquid Chromatography Using Ion-pairing Reagent for Quantitative Assessment of Ceftriaxone in Rat Serum and Cerebrospinal Fluid

Volume:16
Swarupanjali Padhi*, Rupa Mazumder and Shradha Bisth

An UHPLC-UV Method for the Determination of Vancomycin in Human Serum

Volume:16
Fang Fang*, Ning Li, Chunli Xu, Rong Tan, Jihong Yang and Zhichang Zheng

A Validated LC-MS/MS Method for the Determination of Mezlocillin in Plasma: An Adapted Method for Therapeutic Drug Monitoring in Children

Volume:16
Bo-Hao Tang, Min Kan, Xin-Mei Yang, Rong-Hua Wang, Hai-Yan Shi, Yi Zheng, Guo-Xiang Hao, Lin-Lin Song and Wei Zhao*

Quantitation of Conjugation-related Residual Solvents in Antibody Drug Conjugates using Headspace Gas Chromatography

Volume:16
Ruth V. Zuniga, Jacob Kay, Jason Gruenhagen and Colin D. Medley*

A Validated Method for Separation and Determination of Codeine Phosphate Hemihydrate Impurities in Bilayer Tablet Dosage Form of Naproxen Sodium and Codeine Phosphate by Using UHPLC

Volume:16
Arzu Koparan* and Mine Gökalp

Determination of impurities in Perampanel bulk drugs by High- Performance Liquid Chromatography and Gas Chromatography

Volume:16
Yun-Yan Xia, Qiao-Gen Zou, Yu-Fei Yang, Qian Sun and Cheng-Qun Han

A Highly Sensitive LC–MS/MS Method Development and Validation of Fedratinib in Human Plasma and Pharmacokinetic Evaluation in Healthy Rabbits

Volume:16
Ayesha Begum K*, G Shiva Kumar, Pamu Sandhya and D.V.R.N. Bhikshapathi

Spectroscopic Determination of Dissociation Constants of Some 4- nitrobenzaldehyde-4-substituted phenyl-1-carbonylhydrazones in Sodium Hydroxide Media

Volume:16
Mirjana S. Jankulovska*, Ilinka Spirevska, Vesna Dimova and Milena Jankulovska

Novel Rapid Isocratic RP-HPLC Method for Simultaneous Estimation of Phenylephrine Hydrochloride, Paracetamol, Caffeine, Diphenhydramine Hydrochloride

Volume:16
Revati Sonone, Leena Tandel and Vandana Jain*

Establishment and Validation of an ICP-MS Method for Simultaneous Measurement of 24 Elemental Impurities in Ubenimex APIs According to USP/ICH guidelines

Volume:16
Ming-Juan Zhao, Lei Cheng, Yu-Jia Huang, Ying Tao, Xiao Gu and Jin-Qi Zheng*

Quantification and Pharmacokinetics Study of Pedunculoside in Rats by Using UPLC-MS/MS

Volume:16
Aiping Yang, Jiajia Dong, Huimin Zhao, Qichun Zhang, Xuyu Zhu, Lina Gao, Ning Ding, Caihong Li, Ren Peng, Tulin Lu, Lihong Hu and Xiachang Wang*

Difference of Chemical Compositions in Fu Zheng Fang with Different Dosage Forms Based on HPLC-Q-Exactive Orbitrap/MS Combined with Multivariate Statistical Analysis

Volume:16
Yujiao Hua*, Fen Xie and Shijun Zhou

Validated RP-LC Methods for Investigating the Degradation Behavior of Acefylline: Application for Analysis in Two Binary Mixtures

Volume:16
Ola Mohamed EL-Houssini*, Nagwan Hamdi Zawilla and Mohammad Abdul-Azim Mohammad

Study of Pharmaceutical Excipient PEG400 Alteration of Pharmacokinetics and Tissue Distribution of Main Flavonoids Metabolites of Baicalin

Volume:16
Ya-nan Zhu*, Shuo Zhang*, Min Zhang, Xiao-xia Meng, Peng-jiao Wang, Rong-ping Zhang and Xiu-li Gao*

Method Development of Clarithromycin by Chromophore Addition through Chemical Derivatization

Volume:16
Murad Abualhasan*, Amal Qato, Salam Qrareya and Tasneem Khassib

Metabolic Changes in Hyperlipidemic Rats After the Administration of Xuezhikang

Volume:16
Ke Su, Bingbao Chen, Xiaoting Tu, Luxin Ye, Xiaojie Lu, Zheng Yu, Xianqin Wang* and Xuezhi Yang

Simultaneous Analysis of Sexual Stimulants and Anabolic Steroids as Adulterants in Dietary Supplements by High Performance Liquid Chromatography with Photodiode Array Detection

Volume:16
Carine Viana*, Gabriela Zanella Marcon, Thais Ramos Dal Molin, Denise Bohrer, Paulo Cícero do Nascimento and Leandro M. de Carvalho

Development and Validation of a Stability-indicating HPLC Method for the Analysis of Cabazitaxel in Jevtana® Concentrate-solvent Leftover Samples

Volume:16
Hedvig Arnamo*, Michel Hillebrand , Alwin Huitema , Bastiaan Nuijen , Hilde Rosing and Jos Beijnen

Bio-Analytical Method Development and Validation for Estimation of Zaltoprofen in Human Plasma by Reverse Phase -HPLC Method

Volume:16
Kishor Kumar Erukulla and Suseem S.R*

Using Gold Nanoparticles for Ultra-trace Spectrophotometric Determination of Sitagliptin Drug in Various Real Samples

Volume:16
Maryam Moradi, Mahmoud Reza Sohrabi* and Saeid Mortazavinik

Physicochemical Assessment of Branded and Generic Linezolid Injection from Different Pharmaceutical Manufacturers

Volume:16
Su-hua Zhang , Shan-shan Wei , Zhen-yu Zhu, Ying Chen , Hua-lin Cai and Bi-kui Zhang*

Metabolic Changes in Rat Plasma After Epilepsy by UPLC-MS/MS

Volume:16
Congcong Wen, Caiping Zhou, Yongxi Jin, Yujie Hu, Hongzhe Wang, Xianqin Wang* and Xuezhi Yang

Development and Validation of an RP-HPLC Method for the Simultaneous Determination of LevamisoleHCl and Oxyclozanideand its Application in the Assay of Veterinary Bolus Formulations

Volume:16
Kemal Hussien Seid, Tarekegn Berhanu, Kaleab Asres and Ayenew Ashenef*

Identification, Isolation and Characterization of a Pharmaceutical Impurity in Levocetirizine Hydrochloride

Volume:16
Shuchen Pei, Junlin Chen, Shihao Xia, Jieyu Wang, Buyin Xue, Qunliang Wang and Jun Chen*

A Rapid and Selective UPLC-MS/MS Assay for Accurate Analysis of Apatinib in Rat Plasma and its Application to a Pharmacokinetic Study

Volume:16
Jinglin Gao, Zhangying Feng, Huan Ren, Mengdi Yu, Haidong Wang and Mingxia Wang*

Metabolite Fingerprinting of Novel Streptomyces UK-238 from the Himalayan Forest

Volume:16
Nidhi Srivastava and Indira P. Sarethy *

Calcium/Copper Alginate Framework Doped with CuO Nanoparticles as a Novel Adsorbent for Micro-extraction of Benzodiazepines from Human Serum

Volume:16
Nadereh Rahbar*, Fatemeh Ahmadi, Zahra Ramezani and Masoumeh Nourani

Simultaneous Determination of Four Bioactive Flavonoids in Rat Plasma by UPLC–MS/MS and Comparative Pharmacokinetic Study after Oral Administration of Danyikangtai Powder and Three Compatibilities

Volume:16
Yihe Huang, Yanhui Zhao, Yumeng Zhang, Lin Sun, Chunjie Zhao, Xiangdong Zhang and Min Zhao*

Chemometrics-assisted Spectrophotometric Method for Simultaneous Estimation of Antipsychotic Drugs in Biological Fluid

Volume:16
Mojdeh Alibakhshi, Mahmoud Reza Sohrabi* and Mehran Davallo