Current Pharmaceutical Analysis

Identification of In Vivo Metabolites of a Potential Anti-tumor Drug Candidate AMAC, in Rat Plasma, Urine and Feces Samples Using UHPLC/QTOF /MS/MS

Volume: 17   Issue: 4
Pp: 484-494
Caixia Dou, Minghai Tang, Yuanyuan Xia, Linyu Yang, Xiang Qiu, Yong Li, Haoyu Ye* and Li Wan*
DOI: 10.2174/1573412916666191230124527

Analysis of Nonsteroidal Anti-inflammatory Drugs by using Microfluidic Techniques: A Review

Volume: 17   Issue: 3
Pp: 303-315
Chiara Fanali, Giovanni D’Orazio, Alessandra Gentili and Salvatore Fanali*
DOI: 10.2174/1573412916666200401124059

Chiral Separation of Oxomemazine Enantiomers by HPLC Technique and Enantiomeric Separation Mechanism via Docking Studies

Volume: 17   Issue: 2
Pp: 222-230
Prachi Raikar*, Bannimath Gurupadayya, Subhankar P. Mandal, Maruthi Reddy and Prabitha Prabhakar
DOI: 10.2174/1573412916666191116114546

Metabolite Detection and Profiling Using Analytical Methods

Volume: 17   Issue: 1
Pp: 2-9
Lovekesh Mehta*, Parul Grover, Tanveer Naved and Debaraj Mukherjee
DOI: 10.2174/1573412915666190906142536

Metabolomics Based Comparison on the Biomarkers between Panax Notoginseng and its Counterfeit Gynura Segetum in Rats

Volume: 16   Issue: 8
Pp: 1121-1129
Yin Zhang, Haixia Zhang, Jianfeng Shi, Shoubei Qiu, Qianqian Fei, Fenxia Zhu, Jing Wang, Yiping Huang, Daoquan Tang and Bin Chen*
DOI: 10.2174/1573412915666190802142911

Sequential Injection Chromatography with Monolithic Column for Phenothiazines Assay in Human Urine and Pharmaceutical Formulations

Volume: 16   Issue: 7
Pp: 967-975
Abubakr M. Idris*
DOI: 10.2174/1573412915666190219143750

HPLC-DAD-Q-TOF/MS-Based Screening and Analysis of the Multiple Absorbed Bioactive Components in Rat Serum after Oral Administration of Xiexin Tang

Volume: 16   Issue: 6
Pp: 712-723
Xiaoyu Wang, Shujiao Li, Yuqing Wang* and Rui Hu*
DOI: 10.2174/1573412915666190314130053

Study of the Fragmentation Pathways of Sulfonamides by High-resolution Mass Spectrometry: Application to their Detection in Plasma by Direct Infusion

Volume: 16   Issue: 5
Pp: 513-519
Maroula G. Kokotou*
DOI: 10.2174/1573412915666181205115350

A Suitable Immunosensor for Chloramphenicol Determination: Study of Two Different Competitive Formats

Volume: 16   Issue: 4
Pp: 412-423
Elisabetta Martini, Mauro Tomassetti*, Riccardo Angeloni, Mauro Castrucci and Luigi Campanella
DOI: 10.2174/1573412915666190225163036

Advanced High-Coverage Targeted Metabolomics Method (SWATHtoMRM) for Exploring the Relationship of Follicular Fluid Components with Age

Volume: 16   Issue: 3
Pp: 291-302
Jingyan Song, Tianqi Wang, Jiayin Guo, Ying Guo, Xiaoming Wang, Yi Yang, Kaiyue Xu, Yuanhong Sa, Lihua Yuan, Huaying Jiang and Zhengao Sun*
DOI: 10.2174/1573412915666190218155820

A Novel Potentiometric PVC-membrane Cysteamine-Selective Electrode Based on Cysteamine-Phosphomolybdate Ion-Pair

Volume: 16   Issue: 2
Pp: 168-175
Merve Tumur, Gulsah Saydan Kanberoglu and Fatih Coldur*
DOI: 10.2174/1573412914666181017150529

In vitro Identification of Spinosin Metabolites in Human Liver Microsomes Using a Simple and Sensitive UHPLC-Q-TOF-MS/MS Method

Volume: 16   Issue: 1
Pp: 40-46
Qiaoyue Zhang, Xia Zhang, Yanyan Liu, Changchen Wan, Yupeng Sun and Lantong Zhang*
DOI: 10.2174/1573412914666181003141210

Analytical Method Development for Coq10 Determination in Human Plasma Using HPLC-UV and HPLC/MS/MS

Volume: 15   Issue: 7
Pp: 795-807
Vladlena I. Zozina*, Evgeniy S. Melnikov, Olga A. Goroshko, Liudmila M. Krasnykh and Vladimir G. Kukes
DOI: 10.2174/1573412915666190328215854

Characterization of an Unknown Impurity in Glucosamine Sulfate Sodium Chloride by HPLC-Q-TOF MS and NMR

Volume: 15   Issue: 6
Pp: 650-660
Miao Zhang, Peixi Zhu, Yue Chen, Weifang Ni, Yu Li* and Liya Hong*
DOI: 10.2174/1573412915666190222160957

Dynamic Changes of Eight Bioactive Constituents in Magnoliae Officinalis Cortex Based on UFLC-QTRAP-MS/MS Combined with Grey Relational Analysis

Volume: 15   Issue: 5
Pp: 497-504
Hui Zhao, Ying Yan, Chuan Chai, Li-Si Zou, Xun-hong Liu*, Sheng-Nan Wang and Yu-Jiao Hua
DOI: 10.2174/1573412914666180903123749

Simultaneous Determination of Total Cortisol and Cortisone in Human Plasma by Liquid Chromatography-Tandem Mass Spectrometry: Method Development, Validation and Preliminary Clinical Application

Volume: 15   Issue: 4
Pp: 363-370
Martin Kertys*, Anna Urbanova, Michal Mestanik, Ingrid Tonhajzerova and Juraj Mokry
DOI: 10.2174/1573412914666180427094811

A UPLC-MS/MS Method for Simultaneous Determination of Six Bioactive Compounds in Rat Plasma, and its Application to Pharmacokinetic Studies of Naoshuantong Granule in Rats

Volume: 15   Issue: 3
Pp: 231-242
Ping Wang, Shenmeng Jiang, Yu Zhao, Shuo Sun, Xiaoli Wen, Xingjie Guo* and Zhen Jiang*
DOI: 10.2174/1573412914666180409143452

Simultaneous Determination of Imatinib and N-Desmethyl Imatinib in Rat Plasma and Tissues Using LC-MS/MS

Volume: 15   Issue: 2
Pp: 121-129
Zhi Rao, Bo-xia Li, Yong-Wen Jin, Wen-Kou, Yan-rong Ma, Guo-qiang Zhang, Fan Zhang, Yan Zhou and Xin-an Wu*
DOI: 10.2174/1573412913666170821124952

Rapid Detection of AGs using Microchip Capillary Electrophoresis Contactless Conductivity Detection

Volume: 15   Issue: 1
Pp: 9-16
Gangzhi Zhu, Chunjie Bao, Wenfang Liu, Xingxing Yan, Lili Liu, Jian Xiao and Chuanpin Chen*
DOI: 10.2174/1573412913666170918160004

UPLC-MS for Identification of Quercetin Derivatives in Cuphea glutinosa Cham. & Schltdl (Lythraceae) and Evaluation of Antifungal Potential

Volume: 14   Issue: 6
Pp: 586-594
MarI C. Santos, Lidiane S. Farias, Liara Merlugo, Thayse V. de Oliveira, Fabio S. Barbosa, Alexandre M. Fuentefria, Amelia T. Henriques, Cassia V. Garcia and Andreas S.L. Mendez*
DOI: 10.2174/1573412913666170918150924

Targeting Analysis of Gallic Acid and Bioactive Components in Xuebijing Injection with Loop-based Heart-cutting Two-dimensional Liquid Chromatography

Volume: 14   Issue: 5
Pp: 496-500
Yuanyuan Lin, Cheng Wang, Xiaowei Shao, Liu Yang, Yajing Hou, Huaizhen He and Meng Sun*
DOI: 10.2174/1573412913666170613085815

Advances in Anti-Doping Analytical Approaches: Challenges and Solutions

Volume: 14   Issue: 3
Pp: 167-174
Xianchi Li and Peiying Zhang*
DOI: 10.2174/1573412913666170410125447

Application of a Rapid ESI-MS/MS Method for Quantitative Analysis of ocetaxel in Mouse Biological Matrices Through Direct Injection to Mass Spectrometer

Volume: 14   Issue: 2
Pp: 85-94
Pedram Rafiei, Jane Alcorn and Azita Haddadi*
DOI: 10.2174/1573412913666170210153134

Solid-State Screening and Evaluation of Pioglitazone Hydrochloride

Volume: 14   Issue: 1
Pp: 8-16
B. Poornima, K.V.S.R.G. Prasad and K. Bharathi*
DOI: 10.2174/1573412913666161230160413

Checking Ethanol in Several Pharmaceutical Formulations Using Two Different Enzyme Sensor Methods Working by Different Formats

Volume: 13   Issue: 6
Pp: 543-551
Mauro Tomassetti*, Sheila Pellegrini, Riccardo Angeloni, Giovanni Merola and Luigi Campanella
DOI: 10.2174/1573412912666160805112726

Cloud-Point Extraction Coupled with High-Performance Liquid Chromatography for the Determination and Pharmacokinetic Study of Dipyridamole in Rat Plasma

Volume: 13   Issue: 5
Pp: 481-487
Jiajia Li, Yulan Li, Jingjing Liu, Min Liu and Kang Li*
DOI: 10.2174/1573412913666170329143017

Separation of Metal–Trifluoperazine Hydrochloride Complexes Using Zwitterionic Ion Chromatography (ZIC) Coupled Online with ICP-AES

Volume: 13   Issue: 4
Pp: 328-333
Andreas Seubert and Ashraf Saad Rasheed*
DOI: 10.2174/1573412912666160720114147

Electrochemical DNA Biosensors in Drug Analysis

Volume: 13   Issue: 3
Pp: 195-207
Leyla Karadurmuz, Sevinc Kurbanoglu, Bengi Uslu and Sibel A. Ozkan*
DOI: 10.2174/1573412912666160422152634

Screen-Printed Biosensors in Drug Analysis

Volume: 13   Issue: 2
Pp: 169-174
Maria A. Alonso-Lomillo and Olga Dominguez-Renedo
DOI: 10.2174/1573412912666160922112628

Identification of Degradation Products of Cefoselis Sulfate by HPLC-ESI-Quadrupole Time-Of-Flight-Mass Spectrometry in Aqueous Solutions

Volume: 13   Issue: 1
Pp: 26-30
Przemyslaw Zalewski, Robert Skibinski, Alicja Talaczynska, Magdalena Paczkowska and Judyta Cielecka-Piontek
DOI: 10.2174/1573412912666160422123435

LC-MS for Determination of Three Methoxyflavones from Kaempferia parviflora in rat Plasma and Application to Pharmacokinetic Study

Volume: 12   Issue: 4
Pp: 371-378
Sarunya Tuntiyasawasdikul and Bungorn Sripanidkulchai
DOI: 10.2174/1573412912666151208212025

Simultaneous Quantification of Simvastatin and Simvastatin Acid in Human Plasma with a Highly Sensitive LC-ESI-MS/MS Method: Application to a Pharmacokinetic Study in Healthy Chinese Volunteers with a Fixed Dose of Simvastatin and Extended-Release Niacin Combination Tablet promotion: free to download

Volume: 12   Issue: 2
Pp: 96-106
Qiuying Li, Yan Yang, Guobing Shi, Jie Zhang, Guoqing Li, Yin Sui, Yunbiao Tang and Jingkai Gu
DOI: 10.2174/1573412911666150630182218

High Sensitivity C-reactive Protein and Cardiovascular Risk Prediction promotion: free to download

Volume: 11   Issue: 1
Pp: 60-65
Andreja Trpkovic, Julijana Stanimirovic, Ivana Resanovic, Petar Otasevic, Danimir Jevremovic, Radak Djordje and Esma R. Isenovic
DOI: 10.2174/1573412910666140822003911

Co-Precipitation of Phosphorylated Proteins Using Trivalent Cerium-, Holmium-, and Thulium Cations

Volume: 10   Issue: 3
Pp: 175-184
Matthias Rainer, Yuksel Guzel, Christoph Messner and Gunther Karl Bonn
DOI: 10.2174/1573412910666140521180526

Protective Effect of α-ketobutyrate on Survival of Hippocampal Neurons Challenged with Hydrogen Peroxide Chemistry Mimicking Brain Ischemia

Volume: 10   Issue: 2
Pp: 87-91
Dagmara Jacewicz, Kamila Siedlecka-Kroplewska, Joanna Pranczk, Urszula Popowska, Alicja Kuban-Jankowska, Narcyz Knap, Dariusz Wyrzykowski, Krzysztof Zamojc, Michal Wozniak and Lech Chmurzyrski
DOI: 10.2174/1573412909666131231231631