Current Pharmaceutical Biotechnology

Editor-in-Chief

Nikolaos Labrou
Department of Biotechnology
Agricultural University of Athens
Athens
(Greece)

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Articles Ahead of Print

Analysis of the Differences in the Expression of mRNAs and miRNAs Associated with Drug Resistance in Endometrial Cancer Cells Treated with Salinomycin

Volume:21
Piotr Januszyk*, Krzysztof Januszyk, Magdalena Wierzbik-Strońska, Dariusz Boroń and Beniamin Grabarek

Optimization, Purification and Antitumor Activity of Kodamaeoh MRI ANOMY L-Asparaginase MN611146 Isolated from Banana Peel

Volume:21
Ahmed M. I. Shabana, Omar R. Alfarouk, Nayera A.M. Abdelwahed, Mona A. Esawy* and Yousseria M. Shetaia

Cytotoxic Effects of Blue Scorpion Venom (Rhopalurus junceus) in a Glioblastoma Cell Line Model

Volume:21
Laura Alejandra Lozano-Trujillo, Diana Katherine Garzón-Perdomo, Andrea Catalina Rubio Vargas, Lina Maria de los Reyes, Marco Fidel Avila-Rodriguez*, Olivia Teresa Gonzalez Gay and Liliana Francis Turner

Efficacy of An Aqueous Morinda citrifolia Fruit Extract-Phytosome Gel in Treating Oral Inflammatory Ulcer in Rabbit Model

Volume:21
Sonsawan Kongpuckdee, Suwipa Ungphaiboon, Supreedee Sungkharak, Narubodee Phadoongsombut and Sirima Mahattanadul*

Leveraging on Active Site Similarities; Identification of Potential Inhibitors of Zinc-Finger and UFSP domain Protein (ZUFSP)

Volume:21
Mary B. Ajadi, Opeyemi S. Soremekun, Adeniyi T. Adewumi, Hezekiel M. Kumalo and Mahmoud E.S. Soliman*

Leaf and Fruit Methanolic Extracts of Azadirachta indica Exhibit Anti-fertility Activity on Rats’ Sperm Quality and Testicular Histology

Volume:21
Irais Castillo-Maldonado, Claudia Borjón-Ríos, David Pedroza-Escobar, Ashutosh Sharma, Rubén García-Garza, Agustina Ramírez-Moreno, María del CarmenVega-Menchaca, Mario Alberto Rivera-Guillén and Luis-Benjamín Serrano-Gallardo*

Antimicrobial properties of actively purified secondary metabolites isolated from different marine organisms

Volume:21
Nilushi Indika Bamunu Arachchige, Fazlurrahman Khan and Young-Mog Kim*

HIV-Tuberculous Meningitis Co-infection: A Systematic Review and Meta-analysis

Volume:21
Ali Purmohamad, Taher Azimi, Mohammad Javad Nasiri, Mehdi Goudarzi, Moein Zangiabadian, Hamid Sedighian and Abbas Ali Imani Fooladi*

Palmatine Inhibits Up-Regulation of GRP78 and CALR Protein in a STZ-Induced Diabetic Rat Model

Volume:21
Patrick Nwabueze Okechukwua*, Chan Hor Kuan, Kalpana Eluri, Sophia Ogechi Ekeuku and Gabriele Ruth Anisah Froemming

Roles and Biomedical Applications of Haemolymph Lectin

Volume:21
Rana Kamei, Oinam Sangita Devi, Sorokhaibam Jibankumar Singh and Senjam Sunil Singh*

Clinicopathological Significance of Long Non-Coding RNA GHET1 in Human cancers: A Meta-Analysis

Volume:21
Arash Poursheikhani, Negin Nokhandani*, Hassan Yousefi, Dorsa Morshedi Rad and Amirhossein Sahebkar

Enhanced intracellular delivery of Curcumin by Chitosan-Lipoic acid as reduction-responsive nanoparticles

Volume:21
Somayeh Rezaei, Soheila Kashanian*, Yadollah Bahrami, Hossein Zhaleh and Luis J. Cruz

Evaluation of Variances in VEGF-A-D and VEGFR-1-3 Expression in the Ishikawa Endometrial Cancer Cell Line Treated with Salinomycin and Anti-Angiogenic/Lymphangiogenic Effect

Volume:21
Piotr Kras*, Karol Talkowski, Beniamin Oskar Grabarek, Nina Dziobek, Dariusz Boroń and Marcin Oplawski

Stereoselective pharmacokinetics and chiral inversions of some chiral hy-droxy group drugs

Volume:21
Fuxin Chen*, Qiaoxiu Bai, Qingfeng Wang, Suying Chen, Xiaoxian Ma, Changlong Cai, Danni Wang, Ahsan Waqas and Pin Gong

Analysis of the primary and post-treatment antibiotic resistance of Helico-bacter pylori in Nanjing area

Volume:21
Zong-Dan Jiang*, Bang-Shun He, Zhen-Yu Zhang, Shu-Kui Wang, Dan Ran and Zhi-Bing Wang

Effects and Mechanisms of Anlotinib and Dihydroartemisinin Combination Therapy in Ameliorating Malignant Biological Behavior of Gastric Cancer Cells

Volume:21
Qiong Luo, Suyun Zhang, Donghuan Zhang, Rui Feng, Sheng Yang*, Nan Li, Xiangqi Chen and Wujin Chen

Biopharmaceutics and Pharmacokinetics of Timosaponin A-III by a Sensitive HPLC-MS/MS Method: Low Bioavailability Resulting from Poor Permeability and Solubility

Volume:21
Hai-Qiao Wang, Xiao-Mei Gong, Fen Lan, Yi-Han Zhang, Jin-Er Xia, Liang Wang, Hai Zhang and Min Liu*

Matrix Metalloproteinase Inspired Therapeutic Strategies for Bone Diseases

Volume:21
Longfa Kou, Xinyu Jiang, Xinlu Lin, Huirong Huang, Jun Wang, Qing Yao* and Ruijie Chen

Development of New Therapeutics to Meet the Current Challenge of Drug Resistant Tuberculosis

Volume:21
Bashir A Sheikh, Basharat A Bhat, Umar Mehraj, Wajahat Mir, Suhail Hamadani and Manzoor A Mir*

The Research Progress of Taxol in Taxus

Volume:21
Fenjuan Shao*, Iain W. Wilson and Deyou Qiu

Evaluation of Changes in the Expression Profile of mRNA and Proteinencoding Adiponectin in Ishikawa Cell Line Under the Influence of Cisplatin – Preliminary Report

Volume:21
Robert Kiełbasiński*, Przemysław Kieszkowski, Beniamin Oskar Grabarek and Dariusz Boroń

Cisplatin Changes Expression of SEMA3B in Endometrial Cancer

Volume:21
Wojciech Peszek*, Piotr Kras, Beniamin Oskar Grabarek, Dariusz Boroń and Marcin Oplawski

Novel Therapeutic Approaches and Targets for Treatment of Psoriasis

Volume:21
Giulia Radi, Anna Campanati*, Federico Diotallevi, Tommaso Bianchelli and Annamaria Offidani

Comparison of Different Molecular Forms of Astaxanthin in Inhibiting Lipogenesis and its Mechanism

Volume:21
Yanqi Li*, Yaxuan Liu, Yingying Tian, Yao Guo, Changhu Xue and Jingfeng Wang

Novel Therapeutic Approaches and Targets for the Treatment of Atopic Dermatitis

Volume:21
Pescitelli Leonardo, Rosi Elia, Ricceri Federica, Pimpinelli Nicola and Prignano Francesca*

The Influence of Salinomycin on the Expression Profile of mRNAs Encoding Selected Caspases and MiRNAs Regulating their Expression in Endometrial Cancer Cell Line

Volume:21
Krzysztof Januszyk*, Piotr Januszyk, Beniamin Oskar Grabarek, Dariusz Boroń and Marcin Oplawski

Effect of the Phytochemical Agents Against the SARS-CoV and Selected Some of them for Application to COVID-19: A Mini-Review

Volume:21
Muhammad Idrees, Shamshad Khan, Nazakat Hussain Memon and Zhiyong Zhang*

Gallic Acid Protects from Acute Multiorgan Injury Induced by Lipopolysaccharide and D-galactosamine

Volume:21
Samrat Rakshit, Satendra Kumar Nirala and Monika Bhadauria*

Proactive Risk Assessment through FMEA of Home Parenteral Nutrition Care Processes: A Survey Analysis

Volume:21
Giulio Toccafondi, Giulia Dagliana, Vittorio Fineschi*, Paola Frati and Riccardo Tartaglia

Construction and Functional Analysis of the Recombinant Bacteriocins Weissellicin-MBF from Weissella confusa MBF8-1

Volume:21
Amarila Malik*, Elita Yuliantie, Nisa Yulianti Suprahman, Theresa Linardi, Angelina Wening Widiyanti, Jeanita Haldy, Catherine Tjia and Hiroshi Takagi

The Spectrum of Thiazolidinediones Against Respiratory Tract Pathogenic Bacteria: An In-Vitro and In-Silico Approach

Volume:21
Mohammed Al bratty, Ayman Qasem Hakami, Hatim Ahmad Masmali, Md Shamsher Alam, Hassan Ahmad Alhazmi, Neelaveni Thangavel*, Asim Najmi, Sivakumar Sivagurunathan Moni and Anzarul Haque

Lignans and Polyphenols of Phyllanthus amarus Schumach and Thonn Induce Apoptosis in HCT116 Human Colon Cancer Cells through Caspases–Dependent Pathway

Volume:21
Shimaa Ibrahim Abdelmenym Mohamed, Ibrahim Jantan*, Mohd Azlan Nafiah, Mohamed Ali Seyed and Kok Meng Chan

Salinomycin Modulates the Expression of mRNAs and miRNAs Related to Stemness in Endometrial Cancer

Volume:21
Karol Talkowski*, Kamil Kiełbasiński, Wojciech Peszek, Beniamin Oskar Grabarek, Dariusz Boroń and Marcin Oplawski

Oleamide in Ipomoea and Dillenia Species and Inflammatory Activity Investigated through Ion Channel Inhibition

Volume:21
Unchaleeporn Ameamsri, Arunrat Chaveerach, Runglawan Sudmoon, Tawatchai Tanee*, Steve Peigneur and Jan Tytgat

CRISPR Genome Editing Technology and its Application in Genetic Diseases: A Review

Volume:21
Sepideh Khatibi, Amirhossein Sahebkar* and Seyed Hamid Aghaee Bakhtiari

Drug Delivery Assessment of a Novel Triple Antibiotic-Eluting Injectable Platelet-Rich Fibrin Scaffold: An In Vitro Study

Volume:21
Azade Rafiee, Mahtab Memarpour, Sara Taghvamanesh, Forough Karami, Somayeh Karami and Mohammad Hossein Morowvat*

e-Membranome: A Database for Genome-Wide Analysis of Escherichia coli Outer Membrane Proteins

Volume:21
Kang Mo Lee, Seung-Hak Cho*, Cheorl-Ho Kim, Jong Hyun Kim and Sung Soon Kim

Role of P-gp and HDAC2 and their Reciprocal Relationship in Uncontrolled Asthma

Volume:21
Ravi Mishra, Rachna Chaturvedi, Zia Hashim*, Alok Nath, Ajmal Khan, Mansi Gupta, Harshit Singh and Vikas Agarwal

The Protective of Baicalin on Myocardial Ischemia-Reperfusion Injury

Volume:21
Xiaoli Liu, Shanshan Zhang, Chaoyue Xu, Yongchao Sun, Shujian Sui*, Zhaohua Zhang and Yun Luan

Oleophylic Nanospheres Self-Assembly by Emulsion Technique Utilizing the Automatic Nanoscalar Interfacial Alternation (ANIAE)

Volume:21
Hao Ran, Weibin Liu, Xin Pan, Chuanbin Wu*, Guilan Quan, Ying Huang and Yingtong Cui

Icariin accelerate fracture healing via activation of WNT1/β-catenin osteogenic signaling pathway

Volume:21
Xiao-Yun Zhang, Yue-Ping Chen*, Chi Zhang, Xuan Zhang, Tian Xia, Jie Han, Nan Yang, Shi-Lei Song and Can-hong Xu

Noncoding RNAs in Medicinal Plants and their Regulatory Roles in Bioactive Compound Production

Volume:21
Caili Li, Meizhen Wang, Xiaoxiao Qiu, Hong Zhou and Shanfa Lu*

Global Trends in Cannabis and Cannabidiol Research from the Year 1940 to 2019

Volume:21
Jingting Liu, Haimei Chen, Steven Newmaster, Shubin Wang and Chang Liu*

The P-MAPA Immunomodulator Partially Prevents Apoptosis Induced by Zika Virus Infection in THP-1 Cells

Volume:21
Morganna C. Lima, Elisa A. N. Azevedo, Clarice N. L. de Morais, Larissa I. O. de Sousa, Bruno M. Carvalho, Iseu N. da Silva and Rafael F. O. Franca*

Potential Pharmaceutical and Food Applications of Postbiotics: A Review

Volume:21
Aziz Homayouni Rad, Amin Abbasi*, Hossein Samadi Kafil and Khudaverdi Ganbarov

Influence of the Intestinal Microbiota on Diabetes Management

Volume:21
Eva Alvarez-Vieites, Aroa López-Santamarina, José Manuel Miranda, Alicia del Carmen Mondragón, Alexandre Lamas, Alejandra Cardelle-Cobas, Carolina Nebot, Carlos Manuel Franco* and Alberto Cepeda

Saponins from the Sea Cucumber Promote the Osteoblast Differentiation in MC3T3-E1 Cells through the Activation of the BMP2/ Smads Pathway

Volume:21
Zhuo Li*, Yingying Tian, Hongge Ma, Meiling Wang, Ziyi Yan, Changhu Xue and Jingfeng Wang

Proteomics Analysis of Trastuzumab Toxicity in the H9c2 Cardiomyoblast Cell Line and its Inhibition by Carvedilol

Volume:21
Elham Beiranvand, Fatemeh Torkashvand, Seyed Nasser Ostad, Mehdi Mirzaie, Esmat Mirabzadeh Ardakani, Fatemeh Zandi, Soroush Sardari, Ghasem Hosseini Salekdeh, Mohammad Ali Shokrgozar and Behrouz Vaziri*

Effect of Salinomycin on Expression Pattern of Genes Associated with Apoptosis in Endometrial Cancer Cell Line

Volume:21
Kamil Kiełbasiński*, Wojciech Peszek, Beniamin Oskar Grabarek, Dariusz Boroń, Magdalena Wierzbik-Strońska and Marcin Oplawski

Targeted Photodynamic Therapy (PDT) of Lung Cancer with Biotinylated Silicon (IV) Phthalocyanine

Volume:21
Wenyi Dong, Ke Li, Shijie Wang, Ling Qiu, Qingzhu Liu, Minhao Xie and Jianguo Lin*

Bioactive Molecules from the Alpinia Genus: A Comprehensive Review

Volume:21
Santwona Dash, Manasa Kumar Panda, Mayanglambam Chandrakumar Singh, Bimal Prasad Jit, Yengkhom Disco Singh and Jayanta Kumar Patra*