Abstract
The scope of organometallic reactions on solid phase has lately expanded to include many new reactions. In this review, we summarise the recent developments in this area, covering reactions such as metathesis, carbene insertion, radical-mediated transformations, the use of organomagnesium, organozinc and organocopper reagents, applications of titanium alkylidenes for alkene synthesis, as well as the Pauson-Khand reaction, hydroformylation and other methods using metal carbonyl reagents. Palladium-catalysed reactions are not included as this area has been recently reviewed (vide infra).
Keywords: combinatorial chemistry, organometallic reactions, metathesis, carbonyl reagents, carbon-carbon bond formation, grignard reaction, hydroxylamines
Current Organic Chemistry
Title: Solid Phase Synthesis Using Organometallic Reagents
Volume: 9 Issue: 8
Author(s): H. Graden and N. Kann
Affiliation:
Keywords: combinatorial chemistry, organometallic reactions, metathesis, carbonyl reagents, carbon-carbon bond formation, grignard reaction, hydroxylamines
Abstract: The scope of organometallic reactions on solid phase has lately expanded to include many new reactions. In this review, we summarise the recent developments in this area, covering reactions such as metathesis, carbene insertion, radical-mediated transformations, the use of organomagnesium, organozinc and organocopper reagents, applications of titanium alkylidenes for alkene synthesis, as well as the Pauson-Khand reaction, hydroformylation and other methods using metal carbonyl reagents. Palladium-catalysed reactions are not included as this area has been recently reviewed (vide infra).
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Cite this article as:
Graden H. and Kann N., Solid Phase Synthesis Using Organometallic Reagents, Current Organic Chemistry 2005; 9 (8) . https://dx.doi.org/10.2174/1385272053764962
DOI https://dx.doi.org/10.2174/1385272053764962 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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