Current Neuropharmacology

Neuropharmacological and Neurogenetic Correlates of Opioid Use Disorder (OUD) As a Function of Ethnicity: Relevance to Precision Addiction Medicine

Volume: 18   Issue: 7
Pp: 578-595
Tomilowo Abijo, Kenneth Blum and Marjorie C. Gondré-Lewis*
DOI: 10.2174/1570159X17666191118125702

Presynaptic Release-regulating Metabotropic Glutamate Receptors: An Update

Volume: 18   Issue: 7
Pp: 655-672
Guendalina Olivero, Matteo Vergassola, Francesca Cisani, Alessandra Roggeri and Anna Pittaluga*
DOI: 10.2174/1570159X17666191127112339

Melatonin and Melatonergic Influence on Neuronal Transcription Factors: Implications for the Development of Novel Therapies for Neurodegenerative Disorders

Volume: 18   Issue: 7
Pp: 563-577
O.J. Onaolapo, A.Y. Onaolapo*, O.A. Olowe, M.O. Udoh, D.O. Udoh and I.T. Nathaniel
DOI: 10.2174/1570159X18666191230114339

Evaluation of Anti-inflammatory Nutraceuticals in LPS-induced Mouse Neuroinflammation Model: An Update

Volume: 18   Issue: 7
Pp: 636-654
Miryam Nava Catorce and Goar Gevorkian*
DOI: 10.2174/1570159X18666200114125628

Pre-clinical to Clinical Translational Failures and Current Status of Clinical Trials in Stroke Therapy: A Brief Review

Volume: 18   Issue: 7
Pp: 596-612
Neha Dhir, Bikash Medhi*, Ajay Prakash, Manoj Kumar Goyal, Manish Modi and Sandeep Mohindra
DOI: 10.2174/1570159X18666200114160844

Role of Oxidative Stress and Metal Toxicity in the Progression of Alzheimer’s Disease

Volume: 18   Issue: 7
Pp: 552-562
Hareram Birla, Tarun Minocha, Gaurav Kumar, Anamika Misra and Sandeep Kumar Singh*
DOI: 10.2174/1570159X18666200122122512

A New Vision of Mitochondrial Unfolded Protein Response to the Sirtuin Family

Volume: 18   Issue: 7
Pp: 613-623
Huidan Weng, Yihong Ma, Lina Chen, Guoen Cai, Zhiting Chen, Shaochuan Zhang* and Qinyong Ye*
DOI: 10.2174/1570159X18666200123165002

How to Find Candidate Drug-targets for Antiepileptogenic Therapy?

Volume: 18   Issue: 7
Pp: 624-635
Nian Yu , Xing-jian Lin* and Qing Di
DOI: 10.2174/1570159X18666200128124338

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Volume: 18   Issue: 7
Pp: 551-551
G. Azizi
DOI: 10.2174/1570159X1807200608124722

Traumatic Brain Injury: A Forensic Approach: A Literature Review

Volume: 18   Issue: 6
Pp: 538-550
Giuseppe Bertozzi, Francesca Maglietta, Francesco Sessa, Edmondo Scoto, Luigi Cipolloni, Giulio Di Mizio, Monica Salerno and Cristoforo Pomara*
DOI: 10.2174/1570159X17666191101123145

Adult Neurogenesis in Epileptogenesis: An Update for Preclinical Finding and Potential Clinical Translation

Volume: 18   Issue: 6
Pp: 464-484
Liying Chen, Yi Wang and Zhong Chen*
DOI: 10.2174/1570159X17666191118142314

Selenium and Neurological Diseases: Focus on Peripheral Pain and TRP Channels

Volume: 18   Issue: 6
Pp: 501-517
Mustafa Nazıroğlu*, Ahmi Öz and Kenan Yıldızhan
DOI: 10.2174/1570159X18666200106152631

The Critical Period for Neuroprotection by Estrogen Replacement Therapy and the Potential Underlying Mechanisms

Volume: 18   Issue: 6
Pp: 485-500
Hang Guo, Min Liu, Lixia Zhang, Long Wang, Wugang Hou, Yaqun Ma* and Yulong Ma*
DOI: 10.2174/1570159X18666200123165652

Current and Future Neuropharmacological Options for the Treatment of Essential Tremor

Volume: 18   Issue: 6
Pp: 518-537
Hortensia Alonso-Navarro, Elena García-Martín , José A.G. Agúndez and Félix J. Jiménez-Jiménez*
DOI: 10.2174/1570159X18666200124145743

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Volume: 18   Issue: 6
Pp: 463-463
Bechan Sharma
DOI: 10.2174/1570159X1806200522120736

Molecular Hybridization as a Tool in the Design of Multi-target Directed Drug Candidates for Neurodegenerative Diseases

Volume: 18   Issue: 5
Pp: 348-407
Vanessa Silva Gontijo, Flávia P. Dias Viegas, Cindy Juliet Cristancho Ortiz, Matheus de Freitas Silva, Caio Miranda Damasio, Mayara Chagas Rosa, Thâmara Gaspar Campos, Dyecika Souza Couto, Kris Simone Tranches Dias and Claudio Viegas*
DOI: 10.2174/1385272823666191021124443

The Potential Role of Dysfunctions in Neuron-Microglia Communication in the Pathogenesis of Brain Disorders

Volume: 18   Issue: 5
Pp: 408-430
Katarzyna Chamera, Ewa Trojan, Magdalena Szuster-Głuszczak and Agnieszka Basta-Kaim*
DOI: 10.2174/1570159X17666191113101629

Neuroprotective Polyphenols: A Modulatory Action on Neurotransmitter Pathways

Volume: 18   Issue: 5
Pp: 431-445
Elzbieta Rebas, Jowita Rzajew, Tomasz Radzik and Ludmila Zylinska*
DOI: 10.2174/1570159X18666200106155127

OMEGA-3 Interventions in Alcohol Dependence and Related Outcomes: A Systematic Review and Propositions

Volume: 18   Issue: 5
Pp: 456-462
José Carlos F. Galduróz*, Andréia Gomes Bezerra, Gabriel Natan Pires, Renata Pauluci and Ana Regina Noto
DOI: 10.2174/1570159X18666200128120729

The Ambiguous Role of Microglia in Aβ Toxicity: Chances for Therapeutic Intervention

Volume: 18   Issue: 5
Pp: 446-455
Sara Merlo, Simona Federica Spampinato, Grazia Ilaria Caruso and Maria Angela Sortino*
DOI: 10.2174/1570159X18666200131105418

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Volume: 18   Issue: 5
Pp: 347-347
A. Fernández Teruel
DOI: 10.2174/1570159X1805200420135549

Drug Choices and Advancements for Managing Depression in Parkinson's Disease

Volume: 18   Issue: 4
Pp: 277-287
Francesca Assogna, Clelia Pellicano, Cinzia Savini, Lucia Macchiusi, Gaia R. Pellicano, Marika Alborghetti, Carlo Caltagirone, Gianfranco Spalletta and Francesco E. Pontieri*
DOI: 10.2174/1570159X17666191016094857

Human Dermal Fibroblast: A Promising Cellular Model to Study Biological Mechanisms of Major Depression and Antidepressant Drug Response

Volume: 18   Issue: 4
Pp: 301-318
Pierre Mesdom, Romain Colle, Elise Lebigot, Séverine Trabado, Eric Deflesselle, Bruno Fève, Laurent Becquemont, Emmanuelle Corruble and Céline Verstuyft*
DOI: 10.2174/1570159X17666191021141057

Targeting the Neuronal Activity of Prefrontal Cortex: New Directions for the Therapy of Depression

Volume: 18   Issue: 4
Pp: 332-346
Xiao-Ting Zhou, Wen-Dai Bao, Dan Liu and Ling-Qiang Zhu*
DOI: 10.2174/1570159X17666191101124017

Chinese Herbal Medicine Interventions in Neurological Disorder Therapeutics by Regulating Glutamate Signaling

Volume: 18   Issue: 4
Pp: 260-276
Yan Liu, Shan Wang, Jun Kan, Jingzhi Zhang, Lisa Zhou, Yuli Huang * and Yunlong Zhang *
DOI: 10.2174/1570159X17666191101125530

Vitamin D and Depression in Women: A Mini-review

Volume: 18   Issue: 4
Pp: 288-300
Mohamed Said Boulkrane, Julia Fedotova*, Valentina Kolodyaznaya, Vincenzo Micale, Filippo Drago, Annemieke Johanna Maria van den Tol and Denis Baranenko
DOI: 10.2174/1570159X17666191108111120

MicroRNAs: The New Challenge for Traumatic Brain Injury Diagnosis

Volume: 18   Issue: 4
Pp: 319-331
Enrica Pinchi*, Cipolloni Luigi, Santoro Paola, Volonnino Gianpietro, Tomassi Raoul, Arcangeli Mauro and Frati Paola
DOI: 10.2174/1570159X17666191113100808

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Volume: 18   Issue: 4
Pp: 259-259
S.M. Nabavi
DOI: 10.2174/1570159X1804200302111549

An Overview of the Heterogeneity of Major Depressive Disorder: Current Knowledge and Future Prospective

Volume: 18   Issue: 3
Pp: 168-187
Kaipuzha Venu Athira, Sikta Bandopadhyay, Pavan Kumar Samudrala, V.G.M. Naidu, Mangala Lahkar and Sumana Chakravarty*
DOI: 10.2174/1570159X17666191001142934

The Kinetic Component in Drug Discovery: Using the Most Basic Pharmacological Concepts to Advance in Selecting Drugs to Combat CNS Diseases

Volume: 18   Issue: 3
Pp: 250-257
Rafael Franco*, Josema Castelló and Enric I. Canela
DOI: 10.2174/1570159X17666191001144309

A Mechanistic Rationale for PDE-4 Inhibitors to Treat Residual Cognitive Deficits in Acquired Brain Injury

Volume: 18   Issue: 3
Pp: 188-201
Rudy Schreiber*, Romain Hollands and Arjan Blokland
DOI: 10.2174/1570159X17666191010103044

Animal Galectins and Plant Lectins as Tools for Studies in Neurosciences

Volume: 18   Issue: 3
Pp: 202-215
João Ronielly Campêlo Araújo*, Cauê Barbosa Coelho, Adriana Rolim Campos, Renato de Azevedo Moreira and Ana Cristina de Oliveira Monteiro-Moreira
DOI: 10.2174/1570159X17666191016092221

The Contribution of Formyl Peptide Receptor Dysfunction to the Course of Neuroinflammation: A Potential Role in the Brain Pathology

Volume: 18   Issue: 3
Pp: 229-249
Ewa Trojan, Natalia Bryniarska, Monika Leśkiewicz, Magdalena Regulska, Katarzyna Chamera, Magdalena Szuster-Głuszczak, Marcello Leopoldo, Enza Lacivita and Agnieszka Basta-Kaim*
DOI: 10.2174/1570159X17666191019170244

Pharmacologic Overview of Chlorogenic Acid and its Metabolites in Chronic Pain and Inflammation

Volume: 18   Issue: 3
Pp: 216-228
Deniz Bagdas*, Zulfiye Gul, Julie A. Meade, Betul Cam, Nilufer Cinkilic and Mine Sibel Gurun
DOI: 10.2174/1570159X17666191021111809

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Volume: 18   Issue: 3
Pp: 167-167
M. Fiore
DOI: 10.2174/1570159X1803200131125725

The Endocannabinoid System May Modulate Sleep Disorders in Aging

Volume: 18   Issue: 2
Pp: 97-108
Eric Murillo-Rodríguez*, Henning Budde, André Barciela Veras, Nuno Barbosa Rocha, Diogo Telles-Correia, Diogo Monteiro, Luis Cid, Tetsuya Yamamoto, Sérgio Machado and Pablo Torterolo
DOI: 10.2174/1570159X17666190801155922

The “Entourage Effect”: Terpenes Coupled with Cannabinoids for the Treatment of Mood Disorders and Anxiety Disorders

Volume: 18   Issue: 2
Pp: 87-96
Sari Goldstein Ferber, Dvora Namdar, Danielle Hen-Shoval, Gilad Eger, Hinanit Koltai, Gal Shoval*, Liat Shbiro and Aron Weller
DOI: 10.2174/1570159X17666190903103923

The Cold Case of Metabotropic Glutamate Receptor 6: Unjust Detention in the Retina?

Volume: 18   Issue: 2
Pp: 120-125
E. Palazzo*, S. Boccella, I. Marabese, G. Pierretti, F. Guida and S. Maione
DOI: 10.2174/1570159X17666191001141849

Modeling Neuronal Diseases in Zebrafish in the Era of CRISPR

Volume: 18   Issue: 2
Pp: 136-152
Angeles Edith Espino-Saldaña, Roberto Rodríguez-Ortiz, Elizabeth Pereida-Jaramillo and Ataúlfo Martínez-Torres*
DOI: 10.2174/1570159X17666191001145550

Amphetamine Use in the Elderly: A Systematic Review of the Literature

Volume: 18   Issue: 2
Pp: 126-135
Karina Lúcia Moreira Sassi, Natalia Pessoa Rocha, Gabriela Delevati Colpo, Vineeth John and Antonio Lucio Teixeira*
DOI: 10.2174/1570159X17666191010093021

Trigeminal Neuralgia: Basic and Clinical Aspects

Volume: 18   Issue: 2
Pp: 109- 119
Erika Ivanna Araya, Rafaela Franco Claudino, Elcio Juliato Piovesan and Juliana Geremias Chichorro*
DOI: 10.2174/1570159X17666191010094350

Epigenetic Effects Mediated by Antiepileptic Drugs and their Potential Application

Volume: 18   Issue: 2
Pp: 153-166
Fan-Cheng Kong, Chun-Lai Ma* and Ming-Kang Zhong
DOI: 10.2174/1570159X17666191010094849

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Volume: 18   Issue: 2
Pp: 83-83
Haroon Khan
DOI: 10.2174/1570159X1802200109162907

Neuron-to-microglia Crosstalk in Psychiatric Disorders promotion: free to download

Volume: 18   Issue: 2
Pp: 84-86
Youn Jung Lee and Yong-Ku Kim*
DOI: 10.2174/1570159X1802200109163818

The Modulation of Pain by Metabotropic Glutamate Receptors 7 and 8 in the Dorsal Striatum

Volume: 18   Issue: 1
Pp: 34-50
Serena Boccella, Ida Marabese, Francesca Guida, Livio Luongo, Sabatino Maione and Enza Palazzo*
DOI: 10.2174/1570159X17666190618121859

Zinc-mediated Neurotransmission in Alzheimer's Disease: A Potential Role of the GPR39 in Dementia

Volume: 18   Issue: 1
Pp: 2-13
Michal Rychlik* and Katarzyna Mlyniec
DOI: 10.2174/1570159X17666190704153807

Vasopressin & Oxytocin in Control of the Cardiovascular System: An Updated Review

Volume: 18   Issue: 1
Pp: 14-33
Nina Japundžić-Žigon*, Maja Lozić, Olivera Šarenac and David Murphy
DOI: 10.2174/1570159X17666190717150501

Pharmacological Interventions and Rehabilitation Approach for Enhancing Brain Self-repair and Stroke Recovery

Volume: 18   Issue: 1
Pp: 51-64
Rafał Szelenberger, Joanna Kostka, Joanna Saluk-Bijak and Elżbieta Miller*
DOI: 10.2174/1570159X17666190726104139

Nimodipine Reappraised: An Old Drug With a Future

Volume: 18   Issue: 1
Pp: 65-82
Andrew P. Carlson*, Daniel Hänggi, Robert L. Macdonald and Claude W. Shuttleworth
DOI: 10.2174/1570159X17666190927113021

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Volume: 18   Issue: 1
Pp: 1-1
S. Boehm
DOI: 10.2174/1570159X1801191216143152

Potential Therapeutic Approaches to Alzheimer’s Disease By Bioinformatics, Cheminformatics And Predicted Adme-Tox Tools

Volume: 18   Issue:
Pp: 1-24
Speranta Avram, Maria Mernea*, Carmen Limban, Florin Borcan and Carmen Chifiriuc
DOI: 10.2174/1570159X18666191230120053

Underlying Mechanisms and Potential Therapeutic Molecular Targets in Blood-Brain Barrier Disruption after Subarachnoid Hemorrhage

Volume: 18   Issue:
Pp: 1-12
Yuchen Li, Pei Wu, Ji C. Bihl and Huaizhang Shi*
DOI: 10.2174/1570159X18666200106154203

‘New/Designer Benzodiazepines’: An Analysis of the Literature and Psychonauts’ Trip Reports

Volume: 18   Issue:
Pp: 1-29
Laura Orsolini*, John M. Corkery, Stefania Chiappini, Amira Guirguis, Alessandro Vento, Domenico De Berardis, Duccio Papanti and Fabrizio Schifano
DOI: 10.2174/1570159X18666200110121333

Nightmares and the Cannabinoids

Volume: 18   Issue:
Pp: 1-15
Mortimer Mamelak*
DOI: 10.2174/1570159X18666200114142321

Molecular Mechanism of Autophagy: Its Role in the Therapy of Alzheimer’s Disease

Volume: 18   Issue:
Pp: 1-20
Zhao Yuan, Zhang Yidan, Zhang Jian, Zhang Xiangjian and Yang Guofeng*
DOI: 10.2174/1570159X18666200114163636

Recent Trends in the Management of Alzheimer’s Disease: Current Therapeutic Options and Drug Repurposing Approaches

Volume: 18   Issue:
Pp: 1-15
Rakesh Kumar Singh*
DOI: 10.2174/1570159X18666200128121920

Alzheimer’s Disorder: Epigenetic Connection and Associated Risk Factors

Volume: 18   Issue:
Pp: 1-14
Vivek Kumar Sharma, Vineet Mehta and Thakur Gurjeet Singh*
DOI: 10.2174/1570159X18666200128125641

A Comprehensive Review of Alzheimer’s Association with Related Proteins: Pathological Role and Therapeutic Significance

Volume: 18   Issue:
Pp: 1-22
Deepak Kumar, Aditi Sharma and Lalit Sharma*
DOI: 10.2174/1570159X18666200203101828

Role of Nuclear Factor Kappa B (NF-κB) Signalling in Neurodegenerative Diseases: An Mechanistic Approach

Volume: 18   Issue:
Pp: 1-18
Shareen Singh * and Thakur Gurjeet Singh
DOI: 10.2174/1570159X18666200207120949

Endocannabinoid Receptors in the CNS: Potential Drug Targets for the Prevention and Treatment of Neurologic and Psychiatric Disorders

Volume: 18   Issue:
Pp: 1-19
José Antonio Estrada* and Irazú Contreras
DOI: 10.2174/1570159X18666200217140255

Therapeutic Strategies to Protect the Central Nervous System against Shiga Toxin from Enterohemorrhagic Escherichia coli

Volume: 18   Issue:
Pp: 1-21
Jorge Goldstein, Krista Nuñez-Goluboay and Alipio Pinto*
DOI: 10.2174/1570159X18666200220143001