Current Medicinal Chemistry

Clinical and Translational Research Challenges in Neuroendocrine Tumours open Access plus

Volume: 27   Issue: 29
Pp: 4823-4839
Jorge Barriuso* and Angela Lamarca
DOI:10.2174/0929867327666200207120725

SARS-CoV-2: Recent Reports on Antiviral Therapies Based on Lopinavir/Ritonavir, Darunavir/Umifenovir, Hydroxychloroquine, Remdesivir, Favipiravir and other Drugs for the Treatment of the New Coronavirus open Access plus

Volume: 27   Issue: 27
Pp: 4536-4541
Michele Costanzo, Maria Anna Rachele De Giglio and Giovanni Nicola Roviello*
DOI:10.2174/0929867327666200416131117

Recent Advances in the Understanding of the Reaction Chemistries of the Heme Catabolizing Enzymes HO and BVR Based on High Resolution Protein Structures open Access plus

Volume: 27   Issue: 21
Pp: 3499-3518
Masakazu Sugishima*, Kei Wada and Keiichi Fukuyama*
DOI:10.2174/0929867326666181217142715

FTY720 (Fingolimod) Ameliorates Brain Injury through Multiple Mechanisms and is a Strong Candidate for Stroke Treatment open Access plus

Volume: 27   Issue: 18
Pp: 2979-2993
Zifeng Wang, Masahito Kawabori* and Kiyohiro Houkin
DOI:10.2174/0929867326666190308133732

Carbohydrate Scaffolds for the Study of the Autism-associated Bacterium, Clostridium bolteae open Access plus

Volume: 26   Issue: 35
Pp: 6341-6348
Brittany Pequegnat and Mario A. Monteiro*
DOI:10.2174/0929867326666190225164527

The Interplay between G-quadruplex and Transcription open Access plus

Volume: 26   Issue: 16
Pp: 2898-2917
Nayun Kim*
DOI:10.2174/0929867325666171229132619

Complex Signaling Networks Controlling Dynamic Molecular Changes in Pseudomonas aeruginosa Biofilm open Access plus

Volume: 26   Issue: 11
Pp: 1979-1993
Grzegorz Guła, Agata Dorotkiewicz-Jach, Kamila Korzekwa, Miguel A. Valvano and Zuzanna Drulis-Kawa*
DOI:10.2174/0929867325666180912110151

Lipids as Biomarkers of Cancer and Bacterial Infections open Access plus

Volume: 26   Issue: 11
Pp: 1924-1932
Gerald Larrouy-Maumus *
DOI:10.2174/0929867325666180904120029

Fighting Type-2 Diabetes: Present and Future Perspectives open Access plus

Volume: 26   Issue: 10
Pp: 1891-1907
Cai-Guo Yu, Ying Fu, Yuan Fang, Ning Zhang, Rong-Xin Sun, Dong Zhao, Ying-Mei Feng* and Bao-Yu Zhang*
DOI:10.2174/0929867324666171009115356

Untargeted Metabolomics Provides Insight into the Mechanisms Underlying Resistant Hypertension open Access plus

Volume: 26   Issue: 1
Pp: 232-243
Renata Wawrzyniak, Arlette Yumba Mpanga, Wiktoria Struck-Lewicka, Marta Kordalewska, Katarzyna Polonis, Małgorzata Patejko, Monika Mironiuk, Anna Szyndler, Marzena Chrostowska, Michał Hoffmann, Ryszard T. Smoleński, Roman Kaliszan, Krzysztof Narkiewicz and Michał J. Markuszewski*
DOI:10.2174/0929867324666171006122656

Metabolomic Heterogeneity of Urogenital Tract Cancers Analyzed by Complementary Chromatographic Techniques Coupled with Mass Spectrometry open Access plus

Volume: 26   Issue: 1
Pp: 216-231
Arlette Yumba-Mpanga, Wiktoria Struck-Lewicka, Renata Wawrzyniak, Marcin Markuszewski, Marek Roslan, Roman Kaliszan and Michał Jan Markuszewski*
DOI:10.2174/0929867324666171006150326

Osteoporosis: Current and Emerging Therapies Targeted to Immunological Checkpoints open Access plus

Volume: 26  
Pp: 1-16
Massimo De Martinis, Maria Maddalena Sirufo and Lia Ginaldi*
DOI:10.2174/0929867326666190730113123

The Role of Mitochondrial Dysfunction in the Progression of Alzheimer’s Disease open Access plus

Volume: 25   Issue: 40
Pp: 5578-5587
Claus Desler, Meryl S. Lillenes, Tone Tønjum and Lene Juel Rasmussen*
DOI:10.2174/0929867324666170616110111

Mycosporine-Like Amino Acids for Skin Photoprotection open Access plus

Volume: 25   Issue: 40
Pp: 5512-5527
Karl P. Lawrence, Paul F. Long and Antony R. Young*
DOI:10.2174/0929867324666170529124237

Common Aspects Influencing the Translocation of SERS to Biomedicine open Access plus

Volume: 25   Issue: 35
Pp: 4638-4652
Dionysia Tsoutsi, Marcos Sanles-Sobrido, Andreu Cabot and Pilar-Rivera Gil*
DOI:10.2174/0929867325666180105101841

Emerging Technologies for Cancer Research: Towards Personalized Medicine with Microfluidic Platforms and 3D Tumor Models open Access plus

Volume: 25   Issue: 35
Pp: 4616-4637
Matteo Turetta, Fabio Del Ben, Giulia Brisotto, Eva Biscontin, Michela Bulfoni, Daniela Cesselli, Alfonso Colombatti, Giacinto Scoles, Giuseppe Gigli and Loretta L. del Mercato*
DOI:10.2174/0929867325666180605122633

Coating Matters: Review on Colloidal Stability of Nanoparticles with Biocompatible Coatings in Biological Media, Living Cells and Organisms open Access plus

Volume: 25   Issue: 35
Pp: 4553-4586
Jonas Schubert* and Munish Chanana*
DOI:10.2174/0929867325666180601101859

Vitamin D Receptor: A Novel Therapeutic Target for Kidney Diseases open Access plus

Volume: 25   Issue: 27
Pp: 3256-3271
Shikun Yang, Aimei Li, JianWen Wang, Jun Liu, Yachun Han, Wei Zhang, Yan Chun Li and Hao Zhang*
DOI:10.2174/0929867325666180214122352

Serotonin Receptor Binding Characteristics of Geissoschizine Methyl Ether, an Indole Alkaloid in Uncaria Hook open Access plus

Volume: 25   Issue: 9
Pp: 1036-1045
Yasushi Ikarashi, Kyoji Sekiguchi and Kazushige Mizoguchi*
DOI:10.2174/0929867324666170320114713

NGS Technologies as a Turning Point in Rare Disease Research , Diagnosis and Treatment open Access plus

Volume: 25   Issue: 3
Pp: 404-432
Ana Fernandez-Marmiesse*, Sofia Gouveia and Maria L. Couce *
DOI:10.2174/0929867324666170718101946

Immunocontraception: Filamentous Bacteriophage as a Platform for Vaccine Development open Access plus

Volume: 24   Issue: 35
Pp: 3907-3920
Tatiana I. Samoylova*, Timothy D. Braden, Jennifer A. Spencer and Frank F. Bartol
DOI:10.2174/0929867324666170911160426

A Therapeutic Connection between Dietary Phytochemicals and ATP Synthase open Access plus

Volume: 24   Issue: 35
Pp: 3894-3906
Zulfiqar Ahmad*, Sherif S. Hassan and Sofiya Azim
DOI:10.2174/0929867324666170823125330

A Systematic Analysis of Physicochemical and ADME Properties of All Small Molecule Kinase Inhibitors Approved by US FDA from January 2001 to October 2015 open Access plus

Volume: 24   Issue: 29
Pp: 3159-3184
Zhihong O`Brien and Mehran F. Moghaddam*
DOI:10.2174/0929867324666170523124441

Major Developments in the Design of Inhibitors along the Kynurenine Pathway open Access plus

Volume: 24   Issue: 23
Pp: 2471-2495
Kelly R. Jacobs, Gloria Castellano-Gonzalez , Gilles J. Guillemin * and David B. Lovejoy *
DOI:10.2174/0929867324666170502123114

Therapeutic Strategies of Plant-derived Compounds for Diabetes Via Regulation of Monocyte Chemoattractant Protein-1 open Access plus

Volume: 24   Issue: 14
Pp: 1453-1468
Magdalena Czemplik*, Anna Kulma, Yu Fu Wang and Jan Szopa
DOI:10.2174/0929867324666170303162935

Recent Advances of Graphene-based Hybrids with Magnetic Nanoparticles for Biomedical Applications open Access plus

Volume: 24   Issue: 5
Pp: 529-536
Nuria Alegret, Alejandro Criado and Maurizio Prato*
DOI:10.2174/0929867323666161216144218

Xanthine Oxidoreductase in Drug Metabolism: Beyond a Role as a Detoxifying Enzyme open Access plus

Volume: 23   Issue: 35
Pp: 4027-4036
Maria Giulia Battelli, Letizia Polito, Massimo Bortolotti and Andrea Bolognesi
DOI:10.2174/0929867323666160725091915

Osteoimmunology and Beyond open Access plus

Volume: 23   Issue: 33
Pp: 3754-3774
Lia Ginaldi and Massimo De Martinis
DOI:10.2174/0929867323666160907162546

Targeting the Microglial Signaling Pathways: New Insights in the Modulation of Neuropathic Pain open Access plus

Volume: 23   Issue: 26
Pp: 2908-2928
Katarzyna Popiolek-Barczyk and Joanna Mika
DOI:10.2174/0929867323666160607120124

Why Antidiabetic Vanadium Complexes are Not in the Pipeline of “Big Pharma” Drug Research? A Critical Review open Access plus

Volume: 23   Issue: 25
Pp: 2874-2891
Thomas Scior, Jose Antonio Guevara-Garcia, Quoc-Tuan Do, Philippe Bernard and Stefan Laufer
DOI:10.2174/0929867323666160321121138

A Compendium of Volatile Organic Compounds (VOCs) Released By Human Cell Lines open Access plus

Volume: 23   Issue: 20
Pp: 2112-2131
Wojciech Filipiak, Pawel Mochalski, Anna Filipiak, Clemens Ager, Raquel Cumeras, Cristina E. Davis, Agapios Agapiou, Karl Unterkofler and Jakob Troppmair
DOI:10.2174/0929867323666160510122913

Structure and Expression of Different Serum Amyloid A (SAA) Variants and their Concentration-Dependent Functions During Host Insults open Access plus

Volume: 23   Issue: 17
Pp: 1725-1755
Mieke De Buck, Mieke Gouwy, Ji Ming Wang, Jacques Van Snick, Ghislain Opdenakker, Sofie Struyf and Jo Van Damme
DOI:10.2174/0929867323666160418114600

Current Advances in Developing Inhibitors of Bacterial Multidrug Efflux Pumps open Access plus

Volume: 23   Issue: 10
Pp: 1062-1081
Hannah Y. Mahmood, Shirin Jamshidi, J. Mark Sutton and Khondaker M. Rahman
DOI:10.2174/0929867323666160304150522

Food Proteins as Source of Opioid Peptides-A Review open Access plus

Volume: 23   Issue: 9
Pp: 893-910
Swati Garg, Kulmira Nurgali and Vijay Kumar Mishra
DOI:10.2174/0929867323666160219115226

Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases open Access plus

Volume: 23   Issue: 8
Pp: 792-815
Marisa Cabeza, Araceli Sánchez-Márquez, Mariana Garrido, Aylín Silva and Eugene Bratoeff
DOI:10.2174/0929867323666160210125642

Serotonin 1A Receptors on Astrocytes as a Potential Target for the Treatment of Parkinson’s Disease open Access plus

Volume: 23   Issue: 7
Pp: 686-700
Ikuko Miyazaki and Masato Asanuma
DOI:10.2174/0929867323666160122115057

Role of Tyrosine Isomers in Acute and Chronic Diseases Leading to Oxidative Stress - A Review open Access plus

Volume: 23   Issue: 7
Pp: 667-685
Gergő A. Molnár, Szilárd Kun, Eszter Sélley, Melinda Kertész, Lívia Szélig, Csaba Csontos, Katalin Böddi, Lajos Bogár, Attila Miseta and István Wittmann
DOI:10.2174/0929867323666160119094516

Eosinophils in Cancer: Favourable or Unfavourable? open Access plus

Volume: 23   Issue: 7
Pp: 650-666
Samy Sakkal, Sarah Miller, Vasso Apostolopoulos and Kulmira Nurgali
DOI:10.2174/0929867323666160119094313

A “Double-Edged” Scaffold: Antitumor Power within the Antibacterial Quinolone open Access plus

Volume: 23   Issue: 6
Pp: 520-577
Gregory S. Bisacchi and Michael R. Hale
DOI:10.2174/0929867323666151223095839

Action of Nanoparticles on Platelet Activation and Plasmatic Coagulation open Access plus

Volume: 23   Issue: 5
Pp: 408-430
Eleonore Fröhlich
DOI:10.2174/0929867323666160106151428

Lipoprotein-Related and Apolipoprotein-Mediated Delivery Systems for Drug Targeting and Imaging open Access plus

Volume: 22   Issue: 31
Pp: 3631-3651
Gunter Almer, Harald Mangge, Andreas Zimmer and Ruth Prassl
DOI:10.2174/0929867322666150716114625

Non-Traditional Systemic Treatments for Diabetic Retinopathy: An Evidence-Based Review open Access plus

Volume: 22   Issue: 21
Pp: 2580-2589
Rafael Simo, Stefania Ballarini, Jose Cunha-Vaz, Linong Ji, Hermann Haller, Paul Zimmet and Tien Y Wong
DOI:10.2174/0929867322666150520095923

Bacteriophages and Phage-Derived Proteins – Application Approaches open Access plus

Volume: 22   Issue: 14
Pp: 1757-1773
Zuzanna Drulis-Kawa, Grazyna Majkowska-Skrobek and Barbara Maciejewska
DOI:10.2174/0929867322666150209152851

Key Sites for P2X Receptor Function and Multimerization: Overview of Mutagenesis Studies on a Structural Basis open Access plus

Volume: 22   Issue: 7
Pp: 799-818
Ralf Hausmann, Achim Kless and Gunther Schmalzing
DOI:10.2174/0929867322666141128163215

Recent Development of Multifunctional Agents as Potential Drug Candidates for the Treatment of Alzheimer’s Disease open Access plus

Volume: 22   Issue: 3
Pp: 373-404
Natalia Guzior, Anna Wieckowska, Dawid Panek and Barbara Malawska
DOI:10.2174/0929867321666141106122628

Novel Strategies for Preventing Diabetes and Obesity Complications with Natural Polyphenols open Access plus

Volume: 22   Issue: 1
Pp: 150-164
C. Carpene, S. Gomez-Zorita, S. Deleruyelle and M.A. Carpene
DOI:10.2174/0929867321666140815124052

Interactions Between Nanosized Materials and the Brain open Access plus

Volume: 21   Issue: 37
Pp: 4200-4214
M. Simko and Mats-Olof Mattsson
DOI:10.2174/0929867321666140716100449

A Common Molecular Motif Characterizes Extracellular Allosteric Enhancers of GPCR Aminergic Receptors and Suggests Enhancer Mechanism of Action open Access plus

Volume: 21   Issue: 32
Pp: 3673-3686
Robert Root-Bernstein and Patrick F. Dillon
DOI:10.2174/0929867321666140826120604

Atrial Natriuretic Peptide: A Magic Bullet for Cancer Therapy Targeting Wnt Signaling and Cellular pH Regulators open Access plus

Volume: 21   Issue: 21
Pp: 2401-2409
A. Serafino and P. Pierimarchi
DOI:10.2174/0929867321666140205140152

In Vitro and In Vivo Models for Analysis of Resistance to Anticancer Molecular Therapies open Access plus

Volume: 21   Issue: 14
Pp: 1595-1606
Roberta Rosa, Francesca Monteleone, Nicola Zambrano and Roberto Bianco
DOI:10.2174/09298673113209990226

Histopathological Determinants of Tumor Resistance: A Special Look to the Immunohistochemical Expression of Carbonic Anhydrase IX in Human Cancers open Access plus

Volume: 21   Issue: 14
Pp: 1569-1582
G. Ilardi, N. Zambrano, F. Merolla, M. Siano, S. Varricchio, M. Vecchione, G. De Rosa, M. Mascolo and S. Staibano
DOI:10.2174/09298673113209990227

Exogenous Hormonal Regulation in Breast Cancer Cells by Phytoestrogens and Endocrine Disruptors open Access plus

Volume: 21   Issue: 9
Pp: 1129-1145
A. Albini, C. Rosano, G. Angelini, A. Amaro, A.I. Esposito, S. Maramotti, D.M. Noonan and U. Pfeffer
DOI:10.2174/0929867321666131129124640

Pathophysiogenesis of Mesial Temporal Lobe Epilepsy: Is Prevention of Damage Antiepileptogenic? open Access plus

Volume: 21   Issue: 6
Pp: 663-688
G. Curia, C. Lucchi, J. Vinet, F. Gualtieri, C. Marinelli, A. Torsello, L. Costantino and G. Biagini
DOI:10.2174/0929867320666131119152201

Phytoestrogens in Postmenopause: The State of the Art from a Chemical, Pharmacological and Regulatory Perspective open Access plus

Volume: 21   Issue: 4
Pp: 417-436
Elisabetta Poluzzi, Carlo Piccinni, Emanuel Raschi, Angela Rampa, Maurizio Recanatini and Fabrizio De Ponti
DOI:10.2174/09298673113206660297

An Update on Autoinflammatory Diseases open Access plus

Volume: 21   Issue: 3
Pp: 261-269
F. Ciccarelli, M. De Martinis and L. Ginaldi
DOI:10.2174/09298673113206660303

An Up-date of Olive Oil Phenols in Inflammation and Cancer: Molecular Mechanisms and Clinical Implications open Access plus

Volume: 20   Issue: 37
Pp: 4758-4776
A. Cárdeno, M. Sánchez-Hidalgo and C. Alarcón-de-la-Lastra
DOI:10.2174/09298673113209990159

Reduction of Breast Cancer Relapses with Perioperative Non-Steroidal Anti-Inflammatory Drugs: New Findings and a Review open Access plus

Volume: 20   Issue: 33
Pp: 4163-4176
Michael Retsky, Romano Demicheli, William J.M. Hrushesky, Patrice Forget, Marc De Kock, Isaac Gukas, Rick A Rogers, Michael Baum, Vikas Sukhatme and Jayant S. Vaidya
DOI:10.2174/09298673113209990250

Medicinal Chemistry of the Epigenetic Diet and Caloric Restriction open Access plus

Volume: 20   Issue: 32
Pp: 4050-4059
S. L. Martin, T. M. Hardy and T. O. Tollefsbol
DOI:10.2174/09298673113209990189

Neuroprotective Properties of Curcumin in Alzheimer’s Disease – Merits and Limitations open Access plus

Volume: 20   Issue: 32
Pp: 3955-3985
Dawn Chin, Patricia Huebbe, Kathrin Pallauf and Gerald Rimbach
DOI:10.2174/09298673113209990210

Free Fatty Acids-Sensing G Protein-Coupled Receptors in Drug Targeting and Therapeutics open Access plus

Volume: 20   Issue: 31
Pp: 3855-3871
Tomo Yonezawa, Riho Kurata, Kaori Yoshida, Masanori A. Murayama, Xiaofeng Cui and Akihiko Hasegawa
DOI:10.2174/09298673113209990168

Tuberculosis Clinical Trial Update and the Current Anti-Tuberculosis Drug Portfolio open Access plus

Volume: 20   Issue: 30
Pp: 3785-3796
Juan Carlos Palomino and Anandi Martin
DOI:10.2174/09298673113209990166

A Novel Promising Therapeutic Option Against Hepatitis C Virus: An Oral Nucleotide NS5B Polymerase Inhibitor Sofosbuvir open Access plus

Volume: 20   Issue: 30
Pp: 3733-3742
I. Gentile, F. Borgia, A. R. Buonomo, G. Castaldo and G. Borgia
DOI:10.2174/09298673113209990178

Reactive Oxygen Species in Cancer Biology and Anticancer Therapy open Access plus

Volume: 20   Issue: 30
Pp: 3677-3692
Y. Yang, S. Karakhanova, J. Werner and A. V. Bazhin
DOI:10.2174/0929867311320999165

MicroRNAs and Cancer Therapy – From Bystanders to Major Players open Access plus

Volume: 20   Issue: 29
Pp: 3561-3573
Cornelia Braicu, George A. Calin and Ioana Berindan-Neagoe
DOI:10.2174/0929867311320290002

Neurodegeneration in the Pathogenesis of Diabetic Retinopathy: Molecular Mechanisms and Therapeutic Implications open Access plus

Volume: 20   Issue: 26
Pp: 3241-3250
Maxwell S. Stem and Thomas W. Gardner
DOI:10.2174/09298673113209990027

Mitochondria Damage in the Pathogenesis of Diabetic Retinopathy and in the Metabolic Memory Associated with its Continued Progression open Access plus

Volume: 20   Issue: 26
Pp: 3226-3233
Renu A. Kowluru
DOI:10.2174/09298673113209990029

Calpains: Potential Targets for Alternative Chemotherapeutic Intervention Against Human Pathogenic Trypanosomatids open Access plus

Volume: 20   Issue: 25
Pp: 3174-3185
M. H. Branquinha, F. A. Marinho, L. S. Sangenito, S. S.C. Oliveira, K. C. Goncalves, V. Ennes-Vidal, C. M. d’Avila-Levy and A. L.S. Santos
DOI:10.2174/0929867311320250010

Aspartic Peptidases of Human Pathogenic Trypanosomatids: Perspectives and Trends for Chemotherapy open Access plus

Volume: 20   Issue: 25
Pp: 3116-3133
L. O. Santos, A. S. Garcia-Gomes, M. Catanho, C. L. Sodre, A. L.S. Santos, M. H. Branquinha and C. M. d’Avila-Levy
DOI:10.2174/0929867311320250007

Parasite Prolyl Oligopeptidases and the Challenge of Designing Chemotherapeuticals for Chagas Disease, Leishmaniasis and African Trypanosomiasis open Access plus

Volume: 20   Issue: 25
Pp: 3103-3115
I. M.D. Bastos, F. N. Motta, P. Grellier and J. M. Santana
DOI:10.2174/0929867311320250006

Synthetic and Natural Protease Inhibitors Provide Insights into Parasite Development, Virulence and Pathogenesis open Access plus

Volume: 20   Issue: 25
Pp: 3078-3102
A. A. Rascon and J. H. McKerrow
DOI:10.2174/0929867311320250005

n-3 Fatty Acids: Role in Neurogenesis and Neuroplasticity open Access plus

Volume: 20   Issue: 24
Pp: 2953-2963
R. Crupi, A. Marino and S. Cuzzocrea
DOI:10.2174/09298673113209990140

An Overview on Natural Polysaccharides with Antioxidant Properties open Access plus

Volume: 20   Issue: 23
Pp: 2899-2913
H. Wang, Y. M. Liu, Z. M. Qi, S. Y. Wang, S. X. Liu, X. Li, H. J. Wang and X. C. Xia
DOI:10.2174/0929867311320230006

Virtual Screening Strategies in Drug Discovery: A Critical Review open Access plus

Volume: 20   Issue: 23
Pp: 2839-2860
A. Lavecchia and C. Di Giovanni
DOI:10.2174/09298673113209990001

Trypanosomatidae Diseases: From the Current Therapy to the Efficacious Role of Trypanothione Reductase in Drug Discovery open Access plus

Volume: 20   Issue: 21
Pp: 2673-2696
L.S.C. Bernardes, C.L. Zani and I. Carvalho
DOI:10.2174/0929867311320210005

Flavonoids in Atherosclerosis: An Overview of Their Mechanisms of Action open Access plus

Volume: 20   Issue: 21
Pp: 2641-2660
G. Siasos, D. Tousoulis, V. Tsigkou, E. Kokkou, E. Oikonomou, M. Vavuranakis, E.K. Basdra, A.G. Papavassiliou and C. Stefanadis
DOI:10.2174/0929867311320210003

Bioavailability of Quercetin: Problems and Promises open Access plus

Volume: 20   Issue: 20
Pp: 2572-2582
X. Cai, Z. Fang, J. Dou, A. Yu and G. Zhai
DOI:10.2174/09298673113209990120

Clinical and Marketed Proteasome Inhibitors for Cancer Treatment open Access plus

Volume: 20   Issue: 20
Pp: 2537-2551
Jiankang Zhang, Peng Wu and Yongzhou Hu
DOI:10.2174/09298673113209990122

Piroxicam-β-Cyclodextrin: A GI Safer Piroxicam open Access plus

Volume: 20   Issue: 19
Pp: 2415-2437
C. Scarpignato
DOI:10.2174/09298673113209990115

Insulin Secretion and Interleukin-1β Dependent Mechanisms in Human Diabetes Remission After Metabolic Surgery open Access plus

Volume: 20   Issue: 18
Pp: 2374-2388
Chih-Yen Chen, Wei-Jei Lee, A. Asakawa, N. Fujitsuka, Keong Chong, Shu-Chun Chen, Shou-Dong Lee and A. Inui
DOI:10.2174/0929867311320180008

1,2,4-Oxadiazoles Identified by Virtual Screening and their Non-Covalent Inhibition of the Human 20S Proteasome open Access plus

Volume: 20   Issue: 18
Pp: 2351-2362
X. Maréchal, E. Genin, L. Qin, O. Sperandio, M. Montes, N. Basse, N. Richy, M.A. Miteva, M. Reboud-Ravaux, J. Vidal and B.O. Villoutreix
DOI:10.2174/0929867311320180006

Luminescent Silica Nanoparticles for Cancer Diagnosis open Access plus

Volume: 20   Issue: 17
Pp: 2195-2211
W. Arap, R. Pasqualini, M. Montalti, L. Petrizza, L. Prodi, E. Rampazzo, N. Zaccheroni and S. Marchio
DOI:10.2174/0929867311320170005

Computational Peptidology: A New and Promising Approach to Therapeutic Peptide Design open Access plus

Volume: 20   Issue: 15
Pp: 1985-1996
P. Zhou, C. Wang, Y. Ren, C. Yang and F. Tian
DOI:10.2174/0929867311320150005

Targeting the Akt Kinase to Modulate Survival, Invasiveness and Drug Resistance of Cancer Cells open Access plus

Volume: 20   Issue: 15
Pp: 1923-1945
Giuliana Cassinelli, Valentina Zuco, Laura Gatti, Cinzia Lanzi, Nadia Zaffaroni, Diego Colombo and Paola Perego
DOI:10.2174/09298673113209990106

Histone Deacetylase Inhibitors: An Attractive Strategy for Cancer Therapy open Access plus

Volume: 20   Issue: 14
Pp: 1858-1886
Jiyang Li, Guangqiang Li and Wenqing Xu
DOI:10.2174/0929867311320140005

RNAi in Clinical Studies open Access plus

Volume: 20   Issue: 14
Pp: 1801-1816
P. Kubowicz, D. Zelaszczyk and E. Pekala
DOI:10.2174/09298673113209990118

Multi-Target Compounds Acting in the Central Nervous System Designed From Natural Products open Access plus

Volume: 20   Issue: 13
Pp: 1673-1685
X. Chen and M. Decker
DOI:10.2174/0929867311320130007