Current Medicinal Chemistry

SARS-CoV-2: Recent Reports on Antiviral Therapies Based on Lopinavir/Ritonavir, Darunavir/Umifenovir, Hydroxychloroquine, Remdesivir, Favipiravir and other Drugs for the Treatment of the New Coronavirus open access plus

Volume:27   Issue:27
Pp: 4536-4541
Michele Costanzo, Maria Anna Rachele De Giglio and Giovanni Nicola Roviello*
DOI: 10.2174/0929867327666200416131117

Osteoporosis: Current and Emerging Therapies Targeted to Immunological Checkpoints open access plus

Volume:27   Issue:37
Pp: 6356-6372
Massimo De Martinis, Maria Maddalena Sirufo and Lia Ginaldi*
DOI: 10.2174/0929867326666190730113123

Aptamer-Based Targeted Drug Delivery Systems: Current Potential and Challenges

Volume:27   Issue:13
Pp: 2189-2219
Fen He, Nachuan Wen, Daipeng Xiao, Jianhua Yan, Hongjie Xiong, Shundong Cai, Zhenbao Liu* and Yanfei Liu*
DOI: 10.2174/0929867325666181008142831

Targeting n-3 Polyunsaturated Fatty Acids in Non-Alcoholic Fatty Liver Disease

Volume:27   Issue:31
Pp: 5250-5272
Rodrigo Valenzuela*, Macarena Ortiz, María Catalina Hernández-Rodas, Francisca Echeverría and Luis Alberto Videla
DOI: 10.2174/0929867326666190410121716

Antimicrobial Capacity of Plant Polyphenols against Gram-positive Bacteria: A Comprehensive Review

Volume:27   Issue:15
Pp: 2576-2606
Francisco Javier Álvarez-Martínez, Enrique Barrajón-Catalán*, José Antonio Encinar, Juan Carlos Rodríguez-Díaz and Vicente Micol
DOI: 10.2174/0929867325666181008115650

Antiviral Activities of Human Host Defense Peptides

Volume:27   Issue:9
Pp: 1420-1443
David C. Brice and Gill Diamond*
DOI: 10.2174/0929867326666190805151654

Recent Progress in Histone Deacetylase Inhibitors as Anticancer Agents

Volume:27   Issue:15
Pp: 2449-2493
Loredana Cappellacci*, Diego R. Perinelli, Filippo Maggi, Mario Grifantini and Riccardo Petrelli*
DOI: 10.2174/0929867325666181016163110

The Mechanism of Action of Praziquantel: Can New Drugs Exploit Similar Mechanisms?

Volume:27   Issue:5
Pp: 676-696
Charlotte M. Thomas and David J. Timson*
DOI: 10.2174/0929867325666180926145537

The Role of Matrix Gla Protein (MGP) in Vascular Calcification

Volume:27   Issue:10
Pp: 1647-1660
Geir Bjørklund*, Erik Svanberg, Maryam Dadar, David J. Card, Salvatore Chirumbolo, Dominic J. Harrington and Jan Aaseth
DOI: 10.2174/0929867325666180716104159

Structural Basis for Inhibition of Enoyl-[Acyl Carrier Protein] Reductase (InhA) from Mycobacterium tuberculosis

Volume:27   Issue:5
Pp: 745-759
Maurício Boff de Ávila, Gabriela Bitencourt-Ferreira and Walter Filgueira de Azevedo*
DOI: 10.2174/0929867326666181203125229

The Role of Diet Related Short-Chain Fatty Acids in Colorectal Cancer Metabolism and Survival: Prevention and Therapeutic Implications

Volume:27   Issue:24
Pp: 4087-4108
Sara Daniela Gomes, Cláudia Suellen Oliveira, João Azevedo-Silva, Marta R. Casanova, Judite Barreto, Helena Pereira, Susana R. Chaves, Lígia R. Rodrigues, Margarida Casal, Manuela Côrte-Real, Fátima Baltazar and Ana Preto*
DOI: 10.2174/0929867325666180530102050

Obesity and Body Composition in Man and Woman: Associated Diseases and the New Role of Gut Microbiota

Volume:27   Issue:2
Pp: 216-229
Ennio Avolio*, Paola Gualtieri , Lorenzo Romano, Claudio Pecorella, Simona Ferraro, Giuseppe Palma, Laura Di Renzo and Antonino De Lorenzo
DOI: 10.2174/0929867326666190326113607

Role of microRNAs in Chronic Lymphocytic Leukemia Pathogenesis

Volume:27   Issue:2
Pp: 282-297
Ehsan Javandoost, Ehsan Firoozi-Majd, Hosein Rostamian, Mohammad Khakpoor- Koosheh and Hamid Reza Mirzaei*
DOI: 10.2174/0929867326666190911114842

Role of Pro-inflammatory Cytokines in Regulation of Skeletal Muscle Metabolism: A Systematic Review

Volume:27   Issue:13
Pp: 2161-2188
Bhawana Sharma and Rajesh Dabur*
DOI: 10.2174/0929867326666181129095309

Structural Basis of Drug Recognition by Human Serum Albumin

Volume:27   Issue:30
Pp: 4907-4931
Loris Leboffe, Alessandra di Masi*, Fabio Polticelli, Viviana Trezza and Paolo Ascenzi
DOI: 10.2174/0929867326666190320105316

B7-H3 Immune Checkpoint Protein in Human Cancer

Volume:27   Issue:24
Pp: 4062-4086
Karine Flem-Karlsen, Øystein Fodstad and Caroline E. Nunes-Xavier*
DOI: 10.2174/0929867326666190517115515

Protective Role of Natural Products in Glioblastoma Multiforme: A Focus on Nitric Oxide Pathway

Volume:28   Issue:2
Pp: 377-400
Amir R. Afshari, Hamid Mollazadeh, Elmira Mohtashami, Arash Soltani, Mohammad Soukhtanloo, Azar Hosseini, Mohammad Jalili-Nik, Mohammad Mahdi Vahedi, Mostafa Karimi Roshan and Amirhossein Sahebkar*
DOI: 10.2174/0929867327666200130104757

Influence of Oxidative Stress on Catalytic and Non-glycolytic Functions of Glyceraldehyde-3-phosphate Dehydrogenase

Volume:27   Issue:13
Pp: 2040-2058
Vladimir I. Muronetz*, Aleksandra K. Melnikova, Luciano Saso and Elena V. Schmalhausen
DOI: 10.2174/0929867325666180530101057

Obesity Therapy: How and Why?

Volume:27   Issue:2
Pp: 174-186
Sara Paccosi, Barbara Cresci, Laura Pala, Carlo Maria Rotella and Astrid Parenti*
DOI: 10.2174/0929867326666190124121725

Polyoxometalates in Biomedicine: Update and Overview

Volume:27   Issue:3
Pp: 362-379
Mirjana B. Čolović, Milan Lacković, Jovana Lalatović, Ali S. Mougharbel, Ulrich Kortz* and Danijela Z. Krstić*
DOI: 10.2174/0929867326666190827153532

Recent Advances in Peptide-Based Approaches for Cancer Treatment

Volume:27   Issue:8
Pp: 1174-1205
Anne C. Conibear, Alanca Schmid, Meder Kamalov, Christian F.W. Becker and Claudia Bello*
DOI: 10.2174/0929867325666171123204851

Role of Resveratrol in Modulating microRNAs in Human Diseases: From Cancer to Inflammatory Disorder

Volume:28   Issue:2
Pp: 360-376
Atefeh Amiri, Maryam Mahjoubin-Tehran, Zatollah Asemi, Alimohammad Shafiee, Sarah Hajighadimi, Sanaz Moradizarmehri, Hamid Reza Mirzaei* and Hamed Mirzaei*
DOI: 10.2174/0929867326666191212102407

Acyclovir in the Treatment of Herpes Viruses – A Review

Volume:27   Issue:24
Pp: 4118-4137
Katarzyna Kłysik, Aneta Pietraszek, Anna Karewicz and Maria Nowakowska*
DOI: 10.2174/0929867325666180309105519

Comprehensive Review on Graphene Oxide for Use in Drug Delivery System

Volume:27   Issue:22
Pp: 3665-3685
Muhammad Daniyal, Bin Liu and Wei Wang*
DOI: 10.2174/13816128256661902011296290

FTY720 (Fingolimod) Ameliorates Brain Injury through Multiple Mechanisms and is a Strong Candidate for Stroke Treatment open access plus

Volume:27   Issue:18
Pp: 2979-2993
Zifeng Wang, Masahito Kawabori* and Kiyohiro Houkin
DOI: 10.2174/0929867326666190308133732