Current Medicinal Chemistry


Atta-ur-Rahman, FRS
(32052 citations)
Kings College
University of Cambridge

Nobel Laureates on Editorial Board

Prof. John Gurdon

Prof. Jean-Marie Lehn

Prof. Ferid Murad

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Volume: 19 Issue: 23, August 2012

EDITORIAL (Hot Topic: Cancer Chemoresistance and DNA Repair)

Volume:19   Issue: 23
Pp: 3857-3857
Simone Mocellin
DOI: 10.2174/092986712802002545
Published on: 19 July, 2012

Synthetic Lethality to Overcome Cancer Drug Resistance

Volume:19   Issue: 23
Pp: 3858-3873
L. Porcelli, A. E. Quatrale, P. Mantuano, N. Silvestris, A. E. Brunetti, H. Calvert, A. Paradiso and A. Azzariti
DOI: 10.2174/092986712802002563
Published on: 19 July, 2012

DNA Repair and Resistance to Topoisomerase I Inhibitors: Mechanisms, Biomarkers and Therapeutic Targets

Volume:19   Issue: 23
Pp: 3874-3885
M. Alagoz, D. C. Gilbert, S. El-Khamisy and A. J. Chalmers
DOI: 10.2174/092986712802002590
Published on: 19 July, 2012

Strategies to Improve the Killing of Tumors Using Temozolomide: Targeting the DNA Repair Protein MGMT

Volume:19   Issue: 23
Pp: 3886-3892
G. Jiang, L. -T. Li, Y. Xin, L. Zhang, Y. -Q. Liu and J. -N. Zheng
DOI: 10.2174/092986712802002446
Published on: 19 July, 2012

Circumventing Melanoma Chemoresistance by Targeting DNA Repair

Volume:19   Issue: 23
Pp: 3893-3899
S. Mocellin, L Bertazza, C. Benna and P. Pilati
DOI: 10.2174/092986712802002509
Published on: 19 July, 2012

Cancer Resistance to Type II Topoisomerase Inhibitors

Volume:19   Issue: 23
Pp: 3900-3906
P. Pilati, D. Nitti and S. Mocellin
DOI: 10.2174/092986712802002473
Published on: 19 July, 2012

Role of PARP Inhibitors in Cancer Biology and Therapy open access plus

Volume:19   Issue: 23
Pp: 3907-3921
D. Davar, J. H. Beumer, L. Hamieh and H. Tawbi
DOI: 10.2174/092986712802002464
Published on: 19 July, 2012

Base Excision Repair: Contribution to Tumorigenesis and Target in Anticancer Treatment Paradigms

Volume:19   Issue: 23
Pp: 3922-3936
J. L. Illuzzi and D. M. Wilson III
DOI: 10.2174/092986712802002581
Published on: 19 July, 2012

Polo-Like Kinases Inhibitors

Volume:19   Issue: 23
Pp: 3937-3948
L. Garuti, M. Roberti and G. Bottegoni
DOI: 10.2174/092986712802002455
Published on: 20 July, 2012

Coinage Metal Complexes Against Breast Cancer

Volume:19   Issue: 23
Pp: 3949-3956
B. Biersack, A. Ahmad, F. H. Sarkar and R. Schobert
DOI: 10.2174/092986712802002482
Published on: 20 July, 2012

Subtype-Selective Dopamine Receptor Radioligands for PET Imaging: Current Status and Recent Developments

Volume:19   Issue: 23
Pp: 3957-3966
A. Banerjee and O. Prante
DOI: 10.2174/092986712802002518
Published on: 20 July, 2012

Palladacycles as Antimicrobial Agents

Volume:19   Issue: 23
Pp: 3967-3981
A. -S.S.H. Elgazwy, N. S.M. Ismail, S. R. Atta-Allah, M. T. Sarg, D. H.S. Soliman, M. Y. Zaki and M. A. Elgamas
DOI: 10.2174/092986712802002527
Published on: 20 July, 2012

Recent Advances in Non-Peptidomimetic Dipeptidyl Peptidase 4 Inhibitors: Medicinal Chemistry and Preclinical Aspects

Volume:19   Issue: 23
Pp: 3982-3999
Y. Liu, Y. Hu and T. Liu
DOI: 10.2174/092986712802002491
Published on: 20 July, 2012

Glutathione-Related Factors and Oxidative Stress in Autism, A Review open access plus

Volume:19   Issue: 23
Pp: 4000-4005
A. Ghanizadeh, S. Akhondzadeh, M. Hormozi, A. Makarem, M. Abotorabi-Zarchi and A. Firoozabadi
DOI: 10.2174/092986712802002572
Published on: 20 July, 2012

Anti-Inflammatory Effect of 3,4-DHPEA-EDA [2-(3,4 -Hydroxyphenyl) ethyl (3S, 4E)- 4-Formyl-3-(2-Oxoethyl)Hex-4-Enoate] on Primary Human Vascular Endothelial Cells

Volume:19   Issue: 23
Pp: 4006-4013
G. Sindona, A. Caruso, A. Cozza, S. Fiorentini, B. Lorusso, E. Marini, M. Nardi, A. Procopio and S. Zicari
DOI: 10.2174/092986712802002536
Published on: 20 July, 2012

AG490 Promotes HIF-1α Accumulation by Inhibiting Its Hydroxylation

Volume:19   Issue: 23
Pp: 4014-4023
R. Fernandez-Sanchez, S. Berzal, Maria-Dolores Sanchez-Nino, F. Neria, S. Goncalves, O. Calabia, A. Tejedor, M. J. Calzada, C. Caramelo, J. J.P. Deudero and A. Ortiz
DOI: 10.2174/092986712802002554
Published on: 20 July, 2012

Insight into the Structural Determinants of Imidazole Scaffold-Based Derivatives as P38 MAP Kinase Inhibitors by Computational Explorations

Volume:19   Issue: 23
Pp: 4024-4037
C. Huang, Y. Li, H. Ren, J. Wang, L. Shao, S. Zhang, G. Li and L. Yang
DOI: 10.2174/092986712802002608
Published on: 20 July, 2012