Current Medicinal Chemistry


Atta-ur-Rahman, FRS
(32052 citations)
Kings College
University of Cambridge

Nobel Laureates on Editorial Board

Prof. John Gurdon

Prof. Jean-Marie Lehn

Prof. Ferid Murad

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Volume: 18 Issue: 18, June

Editorial [Hot Topic: Phosphoinositide 3-Kinase Pathway Inhibitors: Pharmacology, Metabolism & Drug Development (Guest Editor: Marco Falasca)]

Volume:18   Issue: 18
Pp: 2673-2673
Marco Falasca
DOI: 10.2174/092986711796011210
Published on: 01 March, 2012

Present and Future of PI3K Pathway Inhibition in Cancer: Perspectives and Limitations

Volume:18   Issue: 18
Pp: 2674-2685
E. Ciraolo, F. Morello and E. Hirsch
DOI: 10.2174/092986711796011193
Published on: 01 March, 2012

Progress in the Preclinical Discovery and Clinical Development of Class I and Dual Class I/IV Phosphoinositide 3-Kinase (PI3K) Inhibitors open access plus

Volume:18   Issue: 18
Pp: 2686-2714
S. J. Shuttleworth, F. A. Silva, A. R.L. Cecil, C. D. Tomassi, T. J. Hill, F. I. Raynaud, P. A. Clarke and P. Workman
DOI: 10.2174/092986711796011229
Published on: 01 March, 2012

Targeting the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin Signaling Network in Cancer Stem Cells

Volume:18   Issue: 18
Pp: 2715-2726
A. M. Martelli, C. Evangelisti, M. Y. Follo, G. Ramazzotti, M. Fini, R. Giardino, L. Manzoli, J. A. McCubrey and L. Cocco
DOI: 10.2174/092986711796011201
Published on: 01 March, 2012

Novel Inhibitors of AKT: Assessment of a Different Approach Targeting the Pleckstrin Homology Domain

Volume:18   Issue: 18
Pp: 2727-2742
E. J. Meuillet
DOI: 10.2174/092986711796011292
Published on: 01 March, 2012

mTOR Inhibitors: Facing New Challenges Ahead

Volume:18   Issue: 18
Pp: 2743-2762
I. Mavrommati and T. Maffucci
DOI: 10.2174/092986711796011247
Published on: 01 March, 2012

Targeting PDK1 in Cancer

Volume:18   Issue: 18
Pp: 2763-2769
C. Raimondi and M. Falasca
DOI: 10.2174/092986711796011238
Published on: 01 March, 2012

Novel Circular, Cyclic and Acyclic ψ(CH2O) Containing Peptide Inhibitors of SKI- 1/S1P: Synthesis, Kinetic and Biochemical Evaluations

Volume:18   Issue: 18
Pp: 2770-2782
S. Majumdar, A. Chen, H. Palmer-Smith and A. Basak
DOI: 10.2174/092986711796011265
Published on: 01 March, 2012

Serotonin Receptors of Type 6 (5-HT6): What can we Expect from them?

Volume:18   Issue: 18
Pp: 2783-2790
D. Marazziti, S. Baroni, M. Catena Dell'Osso, F. Bordi and F. Borsini
DOI: 10.2174/092986711796011283
Published on: 01 March, 2012

Adenosine in the Inflamed Gut: A Janus Faced Compound

Volume:18   Issue: 18
Pp: 2791-2815
A. B. Estrela and W.-R. Abraham
DOI: 10.2174/092986711796011274
Published on: 01 March, 2012

Molecular Chaperone Hsp90 as a Target for Oxidant-Based Anticancer Therapies

Volume:18   Issue: 18
Pp: 2816-2825
R. Beck, N. Dejeans, C. Glorieux, R. C. Pedrosa, D. Vasquez, J. A. Valderrama, P. B. Calderon and J. Verrax
DOI: 10.2174/092986711796011256
Published on: 01 March, 2012