Current Medicinal Chemistry

Drug Repurposing: Promises of Edaravone Target Drug in Traumatic Brain Injury

Volume: 28   Issue: 12
Pp: 2369-2391
Zaynab Shakkour, Hawraa Issa, Helene Ismail, Ohanes Ashekyan, Karl John Habashy, Leila Nasrallah, Hussam Jourdi, Eva Hamade, Stefania Mondello, Mirna Sabra*, Kazem Zibara* and Firas Kobeissy*
DOI: 10.2174/0929867327666200812221022

Machine Learning-Based Scoring Functions, Development and Applications with SAnDReS

Volume: 28   Issue: 9
Pp: 1746-1756
Gabriela Bitencourt-Ferreira, Camila Rizzotto and Walter Filgueira de Azevedo Junior*
DOI: 10.2174/0929867327666200515101820

Recent Progress on the Discovery of NLRP3 Inhibitors and their Therapeutic Potential

Volume: 28   Issue: 3
Pp: 569-582
Ma Su, Weiwei Wang, Feng Liu* and Huanqiu Li*
DOI: 10.2174/0929867327666200123093544

SARS-CoV-2: Recent Reports on Antiviral Therapies Based on Lopinavir/Ritonavir, Darunavir/Umifenovir, Hydroxychloroquine, Remdesivir, Favipiravir and other Drugs for the Treatment of the New Coronavirus open access plus

Volume: 27   Issue: 27
Pp: 4536-4541
Michele Costanzo, Maria Anna Rachele De Giglio and Giovanni Nicola Roviello*
DOI: 10.2174/0929867327666200416131117

Role of Alpha-Fetoprotein in Hepatocellular Carcinoma Drug Resistance open access plus

Volume: 28   Issue: 6
Pp: 1126-1142
Wei Li, Kun Liu, Yi Chen, Mingyue Zhu* and Mengsen Li*
DOI: 10.2174/0929867327999200729151247

Dual-target Inhibitors Based on BRD4: Novel Therapeutic Approaches for Cancer

Volume: 28   Issue: 9
Pp: 1775-1795
Sitao Zhang, Yanzhao Chen, Chengsen Tian, Yujing He, Zeru Tian, Yichao Wan and Tingting Liu*
DOI: 10.2174/0929867327666200610174453

Recent Advances in the Development of Casein Kinase 1 Inhibitors

Volume: 28   Issue: 8
Pp: 1585-1604
Sha-Sha Li, Yue-Hui Dong and Zhao-Peng Liu*
DOI: 10.2174/0929867327666200713185413

Insights into RNA-dependent RNA Polymerase Inhibitors as Antiinfluenza Virus Agents

Volume: 28   Issue: 6
Pp: 1068-1090
Ilaria Giacchello, Francesca Musumeci*, Ilaria D’Agostino, Chiara Greco, Giancarlo Grossi and Silvia Schenone
DOI: 10.2174/0929867327666200114115632

Applications of Micro/Nanotechnology in Ultrasound-based Drug Delivery and Therapy for Tumor

Volume: 28   Issue: 3
Pp: 525-547
Suhui Sun, Ping Wang, Sujuan Sun and Xiaolong Liang*
DOI: 10.2174/0929867327666200212100257

Monoclonal Antibodies: A Prospective and Retrospective View

Volume: 28   Issue: 3
Pp: 435-471
Jwala Sivaccumar*, Annamaria Sandomenico*, Luigi Vitagliano and Menotti Ruvo*
DOI: 10.2174/0929867327666200219142231

Recent Advances in c-Jun N-Terminal Kinase (JNK) Inhibitors

Volume: 28   Issue: 3
Pp: 607-627
Gang Li, Wenqing Qi, Xiaoxun Li, Jinwu Zhao, Meihua Luo and Jianjun Chen*
DOI: 10.2174/0929867327666200210144114

Advances in L-Type Calcium Channel Structures, Functions and Molecular Modeling

Volume: 28   Issue: 3
Pp: 514-524
Lei Xu*, Lilei Sun, Liangxu Xie, Shanzhi Mou, Dawei Zhang, Jingyu Zhu and Peng Xu*
DOI: 10.2174/0929867327666200714154059

Heterocycles in the Treatment of Neglected Tropical Diseases

Volume: 28   Issue: 3
Pp: 472-495
Kush K. Maheshwari and Debasish Bandyopadhyay*
DOI: 10.2174/0929867327666200219141652

Antidepressants and Antipsychotic Agents as Repurposable Oncological Drug Candidates

Volume: 28   Issue: 11
Pp: 2137-2174
Michał Antoszczak, Anna Markowska, Janina Markowska and Adam Huczyński*
DOI: 10.2174/0929867327666200907141452

Targeting COVID-19 in Parkinson’s Patients: Drugs Repurposed

Volume: 28   Issue: 12
Pp: 2392-2408
Firoz Anwar*, Salma Naqvi, Fahad A. Al-Abbasi, Nauroz Neelofar, Vikas Kumar, Ankit Sahoo and Mohammad Amjad Kamal*
DOI: 10.2174/0929867327666200903115138

Biosynthesized Quantum Dots as Improved Biocompatible Tools for Biomedical Applications

Volume: 28   Issue: 3
Pp: 496-513
Keru Shi, Xinyi Xu, Hanrui Li, Hui Xie, Xueli Chen and Yonghua Zhan*
DOI: 10.2174/0929867327666200102122737

Advances in Drug Therapy for Systemic Lupus Erythematosus

Volume: 28   Issue: 6
Pp: 1251-1268
Xinghua Zhao, Jiaojiao Zhang, Yutong Liang, Jie Li, Shi Ding, Yang Wang, Ye Chen* and Ju Liu*
DOI: 10.2174/0929867327666200625150408

Metformin: A Growing Journey from Glycemic Control to the Treatment of Alzheimer’s Disease and Depression

Volume: 28   Issue: 12
Pp: 2328-2345
Mohamed El Massry, Lynn M. Alaeddine, Leen Ali, Celine Saad and Assaad A. Eid*
DOI: 10.2174/0929867327666200908114902

Drug Repositioning for the Treatment of Hematologic Disease: Limits, Challenges and Future Perspectives

Volume: 28   Issue: 11
Pp: 2195-2217
Alessandro Allegra, Chiara Imbesi, Alessandra Bitto* and Roberta Ettari
DOI: 10.2174/0929867327999200817102154

A Meta-Analysis of Proteomic Blood Markers of Colorectal Cancer

Volume: 28   Issue: 6
Pp: 1176-1196
Xiang Chen, Jiayu Sun, Xue Wang, Yumeng Yuan, Leshan Cai, Yanxuan Xie, Zhiqiang Fan, Kaixi Liu and Xiaoyang Jiao*
DOI: 10.2174/0929867327666200427094054