ISSN (Print): 1871-529X
ISSN (Online): 2212-4063
Volume 20, 4 Issues, 2020
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ISSN (Print): 1871-529X
ISSN (Online): 2212-4063
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eISBN: 978-981-14-2574-5, 2020
ISBN: 978-981-14-2573-8 ISSN: 2452-3208 (Print) ISSN: 2352-3212 (Online)
Frontiers in Clinical Drug Research – Anti infectives is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the book series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research – Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology.
The sixth volume of this series features these interesting reviews:
- Direct-acting antiviral drugs for treatment of Hepatitis C virus infection
- Plant lattices as anti-infective compounds
- Antimicrobial materials and devices for biomedical applications
- Recent advances in the treatment of toxoplasmosis
- Antimicrobial immunoglobulin prophylaxis and therapy
- Targeting Magnesium Homeostasis as Potential Anti-Infective Strategy Against Mycobacteria
Editor(s): Atta-ur-Rahman and Mohammad Iqbal Choudhary
eISBN: 978-012-803960-1, 2015
ISBN: 978-0-12-803959-5 ISSN: 1574-0889 (Print) ISSN: 2212-1064 (Online)
Editor(s): Javed Ahmad
Co-Editor(s): Javed Ahamad
eISBN: 978-981-14-6448-5, 2020
Natural bioactive compounds from medicinal plants are inexplicably diverse in chemical structure and biological properties. The unmet therapeutic requirements for various diseases serve as a guide for researchers to study natural compounds. These studies are intended to isolate, identify the structural characterization and eventually discover the pharmacological activity of natural compounds from their plant sources with the goal of treating specific diseases.
Bioactive Phytochemicals: Drug Discovery to Product Development explores the scope and approaches of drug discovery from natural products. Chapters in the book cover information about the cultivation, collection and processing of medicinal plants, the methods and high throughput techniques for isolation and characterization of bioactive phytochemicals and pharmacological screening for activity, formulation and quality control. Information about the regulations specified for natural medicinal products in different region of the world is also presented, followed by a concluding chapter devoted to the role of natural herbal products for treatment of human diseases such as cancer, cardiovascular diseases, diabetes, obesity, inflammation and neurological disorders. Each chapter concludes with a general reference section, which is a bibliographic guide to more advanced texts. The contributing authors for this volume are drawn from a rich blend of experts in various areas of herbal medicine which encompass herbal drug discovery to product development.
The concise and organized layout along with a broad coverage of phytochemistry and drug discovery makes this book a suitable reference for students of medicinal chemistry, researchers and industry professionals interested in herbal product development.
Editor(s): Mahesh Bhat and S. L. Belagali
eISBN: 978-981-14-9463-5, 2021
This monograph presents information about the history and evolution of tuberculosis treatment, and the potential of the benzothiazole moiety for anti-tuberculosis (anti-TB) activity. The book introduces the reader to basic information about benzothiazole as a drug candidate before delving into the anti-tubercular properties of derivative compounds in subsequent chapters. The contributors explain quantitative structural-activity relationships of benzothiazole with anti-TB activity along with the importance of in-silico (computer aided) techniques in the drug design process. This is followed by a chapter which details Mycobacterium tuberculosis biology, strains as well as symptoms of tuberculosis infections. The book then explains in-vitro and in-vivo methods used to evaluate drug efficacy against tuberculosis along with the synthesis and anti-TB activity of the benzothiazole derivatives (benzothiazole diamide, benzothiazole guanidinyl derivatives and benzothiazole conjugated pyrazole derivatives).
This book, therefore, is a quick reference on TB diseases, methods of in-silico and in-vitro screening of anti-TB drugs and the importance of the benzothiazole in TB treatment regimens. The book is suitable for readers, researchers and post graduate students who are interested in general tuberculosis drug design, screening and discovery, as well as the application of benzothiazole as an anti-TB drug.