Abstract
Background and aims: Statins are an essential component of the therapeutic approach of patients with atherosclerotic disease. Statin use is also associated with improved peri-operative and long-term outcomes in these patients. We aimed to define the role of statin treatment in patients undergoing percutaneous revascularization procedures. Literature search method: We searched Medline for studies assessing the effect of statin treatment on percutaneous interventions. Literature search results: Early statin treatment is associated with improved outcomes in patients undergoing percutaneous coronary intervention procedures. Current evidence implies that statin treatment may also play a beneficial role in the management of patients undergoing percutaneous renal artery revascularization and endovascular abdominal aortic aneurysm repair, carotid angioplasty/stenting and endovascular peripheral arterial interventions. Conclusions: Preliminary data suggest that statins exert multiple beneficial actions in patients undergoing percutaneous interventions. Future randomized trials are expected to further evaluate the beneficial effects of statins in these procedures.
Keywords: Statins, percutaneous coronary intervention, peripheral arterial disease, endovascular abdominal aortic aneurysm repair, carotid angioplasty, carotid stenting
Current Drug Targets
Title: Statins Exert Multiple Beneficial Effects on Patients Undergoing Percutaneous Revascularization Procedures
Volume: 8 Issue: 8
Author(s): Kosmas I. Paraskevas, Vasilios G. Athyros, Despina D. Briana, Anna I. Kakafika, Asterios Karagiannis and Dimitri P. Mikhailidis
Affiliation:
Keywords: Statins, percutaneous coronary intervention, peripheral arterial disease, endovascular abdominal aortic aneurysm repair, carotid angioplasty, carotid stenting
Abstract: Background and aims: Statins are an essential component of the therapeutic approach of patients with atherosclerotic disease. Statin use is also associated with improved peri-operative and long-term outcomes in these patients. We aimed to define the role of statin treatment in patients undergoing percutaneous revascularization procedures. Literature search method: We searched Medline for studies assessing the effect of statin treatment on percutaneous interventions. Literature search results: Early statin treatment is associated with improved outcomes in patients undergoing percutaneous coronary intervention procedures. Current evidence implies that statin treatment may also play a beneficial role in the management of patients undergoing percutaneous renal artery revascularization and endovascular abdominal aortic aneurysm repair, carotid angioplasty/stenting and endovascular peripheral arterial interventions. Conclusions: Preliminary data suggest that statins exert multiple beneficial actions in patients undergoing percutaneous interventions. Future randomized trials are expected to further evaluate the beneficial effects of statins in these procedures.
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Kosmas I. Paraskevas , Vasilios G. Athyros , Despina D. Briana , Anna I. Kakafika , Asterios Karagiannis and Dimitri P. Mikhailidis , Statins Exert Multiple Beneficial Effects on Patients Undergoing Percutaneous Revascularization Procedures, Current Drug Targets 2007; 8 (8) . https://dx.doi.org/10.2174/138945007781386893
DOI https://dx.doi.org/10.2174/138945007781386893 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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