Current Drug Delivery

Physicochemical Considerations of Tumor Selective Drug Delivery and Activity Confinement with Particular Reference to 1,2-Bis(Sulfonyl)-1- Alkylhydrazines Delivery open Access plus

Volume: 17   Issue: 5
Pp: 362-374
Philip Penketh*, Hugh Williamson and Krishnamurthy Shyam
DOI:10.2174/1567201817666200427215044

A New Food-grade Coenzyme Q10 Formulation Improves Bioavailability: Single and Repeated Pharmacokinetic Studies in Healthy Volunteers open Access plus

Volume: 16   Issue: 8
Pp: 759-767
Giovanna Petrangolini, Massimo Ronchi, Elisabetta Frattini, Eric De Combarieu, Pietro Allegrini and Antonella Riva*
DOI:10.2174/1567201816666190902123147

Electrospun Transdermal Patch for Contraceptive Hormone Delivery open Access plus

Volume: 16   Issue: 6
Pp: 577-583
Mohammad Mofidfar and Mark R. Prausnitz*
DOI:10.2174/1567201816666190308112010

Synthesis, Characterization and Safety Profiling of Eudragit-Based pHResponsive Hydrogels: A Promising Platform for Colonic Delivery of Losartan Potassium open Access plus

Volume: 16   Issue: 6
Pp: 548-564
Shabina Mahmood, Manal Ali Buabeid, Kaleem Ullah, Ghulam Murtaza*, Abdul Mannan and Shujaat Ali Khan*
DOI:10.2174/1567201816666190208165511

Fenofibrate Solid Dispersion Processed by Hot-Melt Extrusion: Elevated Bioavailability and Its Cell Transport Mechanism open Access plus

Volume: 16   Issue: 6
Pp: 538-547
Ting Wen, Boyi Niu, Qiaoli Wu, Yixian Zhou, Xin Pan, Guilan Quan* and Chuanbin Wu
DOI:10.2174/1567201816666190122123044

Simvastatin Loaded Nano Hydroxyapatite in Bone Regeneration: A Study in the Rabbit Femoral Condyle open Access plus

Volume: 16   Issue: 6
Pp: 530-537
Elna Paul Chalisserry, Seung Yun Nam* and Sukumaran Anil
DOI:10.2174/1567201816666190610164303

Talazoparib Loaded Solid Lipid Nanoparticles: Preparation, Characterization and Evaluation of the Therapeutic Efficacy In vitro open Access plus

Volume: 16   Issue: 6
Pp: 511-529
Gamze Guney Eskiler*, Gulsah Cecener, Gokhan Dikmen, Unal Egeli and Berrin Tunca
DOI:10.2174/1567201816666190515105532

In Vitro and In Vivo Evaluation of Olmesartan Medoxomil Microcrystals and Nanocrystals: Preparation, Characterization, and Pharmacokinetic Comparison in Beagle Dogs open Access plus

Volume: 16   Issue: 6
Pp: 500-510
Rong Chai, Hailing Gao, Zhihui Ma, Meng Guo, Qiang Fu, Hongzhuo Liu* and Zhonggui He
DOI:10.2174/1567201816666190627143214

Development and Evaluation of Ropivacaine Loaded Poly(Lactic-Co-Glycolic Acid) Microspheres with Low Burst Release open Access plus

Volume: 16   Issue: 6
Pp: 490-499
Xiqing Zhao, Yue Gao, Xuemei Tang, Wei Lei, Yang Yang, Fanglin Yu, Yan Liu, Meiyan Yang, Yuli Wang, Wei Gong, Zhiping Li*, ChunSheng Gao* and Xingguo Mei
DOI:10.2174/1567201816666190528122137

Bioactive Medications for the Delivery of Platelet Derivatives to Skin Wounds open Access plus

Volume: 16   Issue: 5
Pp: 472-483
Maria Cristina Bonferoni*, Silvia Rossi, Giuseppina Sandri, Carla Caramella, Claudia Del Fante, Cesare Perotti, Dalila Miele, Barbara Vigani and Franca Ferrari
DOI:10.2174/1381612825666190320154406

Medicated Foams and Film Forming Dosage Forms as Tools to Improve the Thermodynamic Activity of Drugs to be Administered Through the Skin open Access plus

Volume: 16   Issue: 5
Pp: 461-471
Chiara G.M. Gennari, Francesca Selmin, Paola Minghetti and Francesco Cilurzo*
DOI:10.2174/1567201816666190118124439

Topical and Transdermal Drug Delivery: From Simple Potions to Smart Technologies open Access plus

Volume: 16   Issue: 5
Pp: 444-460
Heather A.E. Benson*, Jeffrey E. Grice, Yousuf Mohammed, Sarika Namjoshi and Michael S. Roberts
DOI:10.2174/1567201816666190201143457

Cell-penetrating Peptides: Efficient Vectors for Vaccine Delivery open Access plus

Volume: 16   Issue: 5
Pp: 430-443
Jieru Yang, Yacheng Luo, Mohini Anjna Shibu, Istvan Toth* and Mariusz Skwarczynskia*
DOI:10.2174/1567201816666190123120915

Nanomedicines as Drug Delivery Carriers of Anti-Tubercular Drugs: From Pathogenesis to Infection Control open Access plus

Volume: 16   Issue: 5
Pp: 400-429
Afzal Hussain, Sima Singh, Sabya Sachi Das, Keshireddy Anjireddy, Subramanian Karpagam and Faiyaz Shakeel*
DOI:10.2174/1567201816666190201144815

Novel Drug Targets with Traditional Herbal Medicines for Overcoming Endometriosis open Access plus

Volume: 16   Issue: 5
Pp: 386-399
Mert Ilhan, Fatma Tuğçe Gürağaç Dereli and Esra Küpeli Akkol*
DOI:10.2174/1567201816666181227112421

Development and Characterization of Olanzapine Loaded Poly(lactide-co-glycolide) Microspheres for Depot Injection: In vitro and In vivo Release Profiles open Access plus

Volume: 16   Issue: 4
Pp: 375-383
Fahad Pervaiz, Mahmood Ahmad, Lihong Li* and Ghulam Murtaza*
DOI:10.2174/1567201816666181227105930

Design of Experiments (DoE) Approach to Optimize the Sustained Release Microparticles of Gefitinib open Access plus

Volume: 16   Issue: 4
Pp: 364-374
Govind Soni, Khushwant S. Yadav* and Mahesh K. Gupta
DOI:10.2174/1567201816666181227114109

The Effect of Focused Ultrasound on Magnetic Polyelectrolyte Capsules Loaded with Dye When Suspended in Tissue-Mimicking Gel open Access plus

Volume: 16   Issue: 4
Pp: 355-363
Carmen Stavarache*, Mircea Vinatoru and Timothy Mason
DOI:10.2174/1567201816666190103121313

Sucrose Acetate Isobutyrate as an In situ Forming Implant for Sustained Release of Local Anesthetics open Access plus

Volume: 16   Issue: 4
Pp: 331-340
Hanmei Li, Yuling Xu, Yuna Tong, Yin Dan, Tingting Zhou, Jiameng He, Shan Liu* and Yuxuan Zhu*
DOI:10.2174/1567201816666181119112952

Probucol Self-Emulsified Drug Delivery System: Stability Testing and Bioavailability Assessment in Human Volunteers open Access plus

Volume: 16   Issue: 4
Pp: 325-330
Abdelazim Zaghloul*, Ahmed Lila, Fathy Abd-Allah and Aly Nada
DOI:10.2174/1567201816666181227111912

Preparation, Characterization, and In Vitro pH-sensitivity Evaluation of Superparamagnetic Iron Oxide Nanoparticle- Misonidazole pH-sensitive Liposomes open Access plus

Volume: 16   Issue: 3
Pp: 254-267
Bibo Li, Biqiang Li, Daiying He, Changyan Feng, Zhibin Luo* and Mei He*
DOI:10.2174/1567201816666181114124333

Facile Synthesis of Chitosan Based-(AMPS-co-AA) Semi-IPNs as a Potential Drug Carrier: Enzymatic Degradation, Cytotoxicity, and Preliminary Safety Evaluation open Access plus

Volume: 16   Issue: 3
Pp: 242-253
Kaleem Ullah, Muhammad Sohail, Abdul Mannan, Haroon Rashid, Aamna Shah, Ghulam Murtaza and Shujaat Ali Khan*
DOI:10.2174/1567201815666181024152101

Humanin Nanoparticles for Reducing Pathological Factors Characteristic of Age-Related Macular Degeneration open Access plus

Volume: 16   Issue: 3
Pp: 226-232
Aum Solanki, Rudy Smalling, Abraham H. Parola, Ilana Nathan, Roni Kasher, Yashwant Pathak and Vijaykumar Sutariya*
DOI:10.2174/1567201815666181031163111

Formulation and Characterization of Genistein-loaded Nanostructured Lipid Carriers: Pharmacokinetic, Biodistribution and In vitro Cytotoxicity Studies open Access plus

Volume: 16   Issue: 3
Pp: 215-225
Pooja Mittal, Harsh Vrdhan, Gufran Ajmal, Gunjan Bonde, Ramit Kapoor and Brahmeshwar Mishra*
DOI:10.2174/1567201816666181120170137

The Superior Antitumor Effect of Self-Assembled Paclitaxel Nanofilaments for Lung Cancer Cells open Access plus

Volume: 16   Issue: 2
Pp: 171-178
Mengyu He, Jiali Zhu, Na Yu, Hui Kong, Xiaoning Zeng, Weiping Xie* and Huae Xu*
DOI:10.2174/1567201815666181017094003

Continuous Vector-free Gene Transfer with a Novel Microfluidic Chip and Nanoneedle Array open Access plus

Volume: 16   Issue: 2
Pp: 164-170
Dong Huang, Deyao Zhao, Jinhui Li, Yuting Wu, Lili Du, Xin-Hua Xia, Xiaoqiong Li, Yulin Deng, Zhihong Li and Yuanyu Huang*
DOI:10.2174/1567201815666181017095044

Utilization of Apatinib-Loaded Nanoparticles for the Treatment of Ocular Neovascularization open Access plus

Volume: 16   Issue: 2
Pp: 153-163
Kathleen Halasz, Shannon J. Kelly, Muhammad Tajwar Iqbal, Yashwant Pathak and Vijaykumar Sutariya*
DOI:10.2174/1567201815666181017095708

Solid Lipid Nanoparticles and Chitosan-coated Solid Lipid Nanoparticles as Promising Tool for Silybin Delivery: Formulation, Characterization, and In vitro Evaluation open Access plus

Volume: 16   Issue: 2
Pp: 142-152
Vieri Piazzini, Lorenzo Cinci, Mario D'Ambrosio, Cristina Luceri, Anna Rita Bilia and Maria Camilla Bergonzi*
DOI:10.2174/1567201815666181008153602

Permeation Efficacy of a Transdermal Vehicle with Steroidal Hormones and Nonsteroidal Anti-inflammatory Agents as Model Drugs open Access plus

Volume: 16   Issue: 2
Pp: 136-141
Laura A. Junqueira*, Hudson Polonini, Sharlene Loures, Nádia R.B. Raposo, Anderson O. Ferreira and Marcos Antônio F. Brandão
DOI:10.2174/1567201815666181024141849

Improved In vivo Effect of Chrysin as an Absorption Enhancer Via the Preparation of Ternary Solid Dispersion with Brij^®L4 and Aminoclay open Access plus

Volume: 16   Issue: 1
Pp: 86-92
Sang Hoon Lee, Yeo-song Lee, Jae Geun Song and Hyo-Kyung Han *
DOI:10.2174/1567201815666180924151458

Fabrication and Characterization of Electrospun Nanofibers for the Modified Release of the Chronobiotic Hormone Melatonin open Access plus

Volume: 16   Issue: 1
Pp: 79-85
Marilena Vlachou*, Stefanos Kikionis, Angeliki Siamidi, Konstantina Tragou, Stefania Kapoti, Efstathia Ioannou, Vassilios Roussis and Andrew Tsotinis
DOI:10.2174/1567201815666180914095701

The Influence of Microneedles on the Percutaneous Penetration of Selected Antihypertensive Agents: Diltiazem Hydrochloride and Perindopril Erbumine open Access plus

Volume: 15   Issue: 10
Pp: 1449-1458
Emmy Luu, Kevin B. Ita*, Matthew J. Morra and Inna E. Popova
DOI:10.2174/1567201815666180730125941

A Summary of Electrospun Nanofibers as Drug Delivery System: Drugs Loaded and Biopolymers Used as Matrices open Access plus

Volume: 15   Issue: 10
Pp: 1360-1374
Erick José Torres-Martinez, José Manuel Cornejo Bravo*, Aracely Serrano Medina, Graciela Lizeth Pérez González and Luis Jesús Villarreal Gómez*
DOI:10.2174/1567201815666180723114326

Implementing Central Composite Design for Developing Transdermal Diacerein-Loaded Niosomes: Ex vivo Permeation and In vivo Deposition open Access plus

Volume: 15   Issue: 9
Pp: 1330-1342
Diana Edwar Aziz, Aly Ahmed Abdelbary* and Abdelhalim Ibrahim Elassasy
DOI:10.2174/1567201815666180619105419

Optimizing Antitumor Efficacy and Adverse Effects of Pegylated Liposomal Doxorubicin by Scheduled Plasmapheresis: Impact of Timing and Dosing open Access plus

Volume: 15   Issue: 9
Pp: 1261-1270
Romeo Ngoune, Christine Contini, Michael M. Hoffmann, Dominik von Elverfeldt, Karl Winkler and Gerhard Putz*
DOI:10.2174/1567201815666180518125839

Evaluation of Eudragit® Retard Polymers for the Microencapsulation of Alpha-Lipoic Acid open Access plus

Volume: 13   Issue: 7
Pp: 1165-1175
Tiziana M.G. Pecora, Teresa Musumeci, Lucrezia Musumeci, Massimo Fresta and Rosario Pignatello
DOI:10.2174/1567201812666151016095342

Temporal Separation in the Release of Bioactive Molecules from a Moldable Calcium Sulfate Bone Graft Substitute open Access plus

Volume: 11   Issue: 5
Pp: 605-612
Matt E. Brown, Yuan Zou, R. Peyyala, Thomas D. Dziubla and David A. Puleo
DOI:10.2174/1567201811666140616160948

Anatomical and Histological Factors Affecting Intranasal Drug and Vaccine Delivery open Access plus

Volume: 9   Issue: 6
Pp: 566-582
Sveinbjorn Gizurarson
DOI:10.2174/156720112803529828

Enhanced Delivery of Topically-Applied Formulations Following Skin Pre-Treatment with a Hand-Applied, Plastic Microneedle Array open Access plus

Volume: 8   Issue: 5
Pp: 557-565
Dan Duan, Craig Moeckly, Jerry Gysbers, Chris Novak, Gayatri Prochnow, Kris Siebenaler, Leila Albers and Kris Hansen
DOI:10.2174/156720111796642318

Pharmacogenetics of Intestinal Absorption open Access plus

Volume: 5   Issue: 3
Pp: 153-169
Tsutomu Nakamura, Motohiro Yamamori and Toshiyuki Sakaeda
DOI:10.2174/156720108784911749