Current Drug Delivery

Formulation, Characterization and Pharmacokinetics of Long-acting Ceftiofur Hydrochloride Suspension

Volume: 18   Issue: 2
Pp: 224-233
Shuyu Xie*, Xiaoqiu Zhang, Wanhe Luo, Kuiyu Meng, Dongmei Chen, Yuanhu Pan, Yanfei Tao, Lingli Huang, Zhenli Liu, Yulian Wang* and Zonghui Yuan*
DOI: 10.2174/1567201817666200903165119

Application of Hot Melt Extrusion Technology in the Development of Abuse-Deterrent Formulations: An Overview

Volume: 18   Issue: 1
Pp: 4-18
Arun Butreddy, Dinesh Nyavanandi, Sagar Narala, Fischer Austin and Suresh Bandari*
DOI: 10.2174/1567201817999200817151601

Cholesterol-Conjugate as a New Strategy to Improve the Cytotoxic Effect of 5-Fluorouracil on Liver Cancer: Impact of Liposomal Composition

Volume: 17   Issue: 10
Pp: 898-910
Saleh Ayed Alanazi*, Gamaleldin Ibrahim Harisa, Mohammad M. Badran, Nazrul Haq , Awwad Abdoh Radwan , Ashok Kumar , Faiyaz Shakeel and Fars Kaed Alanazi*
DOI: 10.2174/1567201817666200211095452

Increased Toxicity of Doxorubicin Encapsulated into pH-Responsive Poly(β-Amino Ester)-Functionalized MCM-41 Silica Nanoparticles

Volume: 17   Issue: 9
Pp: 799-805
Alejandro Ávila-Ortega, Leydi Maribel Carrillo-Cocom*, Christofer Enmanuel Olán-Noverola, Geovanny I. Nic-Can, Alfredo Rafael Vilchis-Nestor and William Alejandro Talavera-Pech
DOI: 10.2174/1567201817999200728123915

Development of Sustained Release Oseltamivir Phosphate Dry Powder Inhaler: In-Vitro Characterization and In-Vivo Toxicological Studies

Volume: 17   Issue: 8
Pp: 703-710
Harshal Sahastrabudhe, Prathmesh Kenjale and Varsha Pokharkar*
DOI: 10.2174/1567201817666200530201820

Nano-Carriers of Combination Tumor Physical Stimuli-Responsive Therapies

Volume: 17   Issue: 7
Pp: 577-587
Weiqiu Jin, Changzi Dong, Dengtian Yang, Ruotong Zhang, Tianshu Jiang and Daocheng Wu*
DOI: 10.2174/1567201817666200525004225

Application of 3² Full Factorial Design and Desirability Function for Optimizing The Manufacturing Process for Directly Compressible Multi-Functional Co-Processed Excipient

Volume: 17   Issue: 6
Pp: 523-539
Jalpa Patel and Dhaval Mori*
DOI: 10.2174/1567201817666200508094743

Cell-Penetrating Peptides: As a Promising Theranostics Strategy to Circumvent the Blood-Brain Barrier for CNS Diseases

Volume: 17   Issue: 5
Pp: 375-386
Behrang Shiri Varnamkhasti, Samira Jafari, Fereshteh Taghavi, Loghman Alaei, Zhila Izadi, Alireza Lotfabadi, Mojtaba Dehghanian, Mehdi Jaymand, Hossein Derakhshankhah* and Ali Akbar Saboury*
DOI: 10.2174/1567201817666200415111755

Nanotechnological Innovations Enhancing the Topical Therapeutic Efficacy of Quercetin: A Succinct Review

Volume: 17   Issue: 4
Pp: 270-278
Maha Nasr* and Rawan Al-Karaki
DOI: 10.2174/1567201817666200317123224

Delivery Efficacy Differences of Intravenous and Intraperitoneal Injection of Exosomes: Perspectives from Tracking Dye Labeled and MiRNA Encapsulated Exosomes

Volume: 17   Issue: 3
Pp: 186-194
Xueying Zhou, Zhelong Li, Wenqi Sun, Guodong Yang, Changyang Xing* and Lijun Yuan*
DOI: 10.2174/1567201817666200122163251

Antibacterial and Anti-Biofilm Biosynthesised Silver and Gold Nanoparticles for Medical Applications: Mechanism of Action, Toxicity and Current Status

Volume: 17   Issue: 2
Pp: 88-100
Sundos Suleman Ismail Abdalla, Haliza Katas*, Fazren Azmi and Mohd Fauzi Mh Busra
DOI: 10.2174/1567201817666191227094334

Treatment Strategies Against Psoriasis: Principle, Perspectives and Practices

Volume: 17   Issue: 1
Pp: 52-73
Arya Kadukkattil Ramanunny, Sheetu Wadhwa, Sachin Kumar Singh*, Deep Shikha Sharma, Rubiya Khursheed and Ankit Awasthi
DOI: 10.2174/1567201816666191120120551

Drug Delivery and Targeting to the Brain Through Nasal Route: Mechanisms, Applications and Challenges

Volume: 16   Issue: 10
Pp: 887-901
Kanchan Kashyap and Rahul Shukla*
DOI: 10.2174/1567201816666191029122740

pH-Sensitive Magnetite Nanoparticles Modified with Hyperbranched Polymers and Folic Acid for Targeted Imaging and Therapy

Volume: 16   Issue: 9
Pp: 839-848
Seyed Jamal Tabatabaei Rezaei*, Asemeh Mashhadi Malekzadeh, Ali Ramazani and Hassan Niknejad
DOI: 10.2174/1567201816666191002102353

Crossing the Blood-Brain Barrier: A Review on Drug Delivery Strategies for Treatment of the Central Nervous System Diseases

Volume: 16   Issue: 8
Pp: 698-711
Nur Izzati Mansor, Norshariza Nordin*, Farahidah Mohamed, King Hwa Ling, Rozita Rosli and Zurina Hassan
DOI: 10.2174/1567201816666190828153017

Carbohydrates in Vaccine Development

Volume: 16   Issue: 7
Pp: 609-617
Salwa Aljohani, Waleed M. Hussein, Istvan Toth and Pavla Simerska*
DOI: 10.2174/1567201816666190702153612

Fenofibrate Solid Dispersion Processed by Hot-Melt Extrusion: Elevated Bioavailability and Its Cell Transport Mechanism open access plus

Volume: 16   Issue: 6
Pp: 538-547
Ting Wen, Boyi Niu, Qiaoli Wu, Yixian Zhou, Xin Pan, Guilan Quan* and Chuanbin Wu
DOI: 10.2174/1567201816666190122123044

Bioactive Medications for the Delivery of Platelet Derivatives to Skin Wounds open access plus

Volume: 16   Issue: 5
Pp: 472-483
Maria Cristina Bonferoni*, Silvia Rossi, Giuseppina Sandri, Carla Caramella, Claudia Del Fante, Cesare Perotti, Dalila Miele, Barbara Vigani and Franca Ferrari
DOI: 10.2174/1381612825666190320154406

Stimulus Sensitive Smart Nanoplatforms: An Emerging Paradigm for the Treatment of Skin Diseases

Volume: 16   Issue: 4
Pp: 295-311
Divya and Gurpreet Kaur*
DOI: 10.2174/1567201816666190123125813

Graphene Family of Nanomaterials: Reviewing Advanced Applications in Drug delivery and Medicine

Volume: 16   Issue: 3
Pp: 195-214
Kumud Joshi*, Bhaskar Mazumder, Pronobesh Chattopadhyay, Nilutpal Sharma Bora, Danswrang Goyary and Sanjeev Karmakar
DOI: 10.2174/1567201815666181031162208

Current Updates on Bone Grafting Biomaterials and Recombinant Human Growth Factors Implanted Biotherapy for Spinal Fusion: A Review of Human Clinical Studies

Volume: 16   Issue: 2
Pp: 94-110
Guanbao Li*, Pinquan Li, Qiuan Chen, Hnin Ei Thu and Zahid Hussain
DOI: 10.2174/1567201815666181024142354

Nose to Brain Delivery of Galantamine Loaded Nanoparticles: In-vivo Pharmacodynamic and Biochemical Study in Mice

Volume: 16   Issue: 1
Pp: 51-58
Sunena, Shailendra Kumar Singh* and Dina Nath Mishra
DOI: 10.2174/1567201815666181004094707

A Summary of Electrospun Nanofibers as Drug Delivery System: Drugs Loaded and Biopolymers Used as Matrices open access plus

Volume: 15   Issue: 10
Pp: 1360-1374
Erick José Torres-Martinez, José Manuel Cornejo Bravo*, Aracely Serrano Medina, Graciela Lizeth Pérez González and Luis Jesús Villarreal Gómez*
DOI: 10.2174/1567201815666180723114326

The Role of Lipid Nanoparticles and its Surface Modification in Reaching the Brain: An Approach for Neurodegenerative Diseases Treatment

Volume: 15   Issue: 9
Pp: 1218-1220
Sara Hernando, Jose Luis Pedraz, Manoli Igartua* and Rosa Maria Hernandez*
DOI: 10.2174/1567201815666180510103747

Vitamin E TPGS Emulsified Vinorelbine Bitartrate Loaded Solid Lipid Nanoparticles (SLN): Formulation Development, Optimization and In vitro Characterization

Volume: 15   Issue: 8
Pp: 1135-1145
Lakshmi Maurya, Sanjay Singh*, Vijayakumar M. Rajamanickam and Gopeshwar Narayan
DOI: 10.2174/1567201815666180409105410

Biodegradable Microspheres as Intravitreal Delivery Systems for Prolonged Drug Release. What is their Eminence in the Nanoparticle Era?

Volume: 15   Issue: 7
Pp: 930-940
Elisabetta Gavini, Maria C. Bonferoni*, Giovanna Rassu, Antonella Obinu, Franca Ferrari and Paolo Giunchedi
DOI: 10.2174/1567201815666180226121020

Arginine Functionalized Bacterial Cellulose Nanofibers Containing Gel as an Effective Wound Dressing: In vitro and In vivo Evaluation

Volume: 15   Issue: 6
Pp: 840-849
Farideh Feizabadi, Mohsen Minaiyan and Azade Taheri*
DOI: 10.2174/1567201815666180220100154

Influence of Divalent Cation on Morphology and Drug Delivery Efficiency of Mixed Polymer Nanoparticles

Volume: 15   Issue: 5
Pp: 652-657
Ramachandran Deepika, Koyeli Girigoswami, Ramachandran Murugesan and Agnishwar Girigoswami*
DOI: 10.2174/1567201814666170825160617

Nanomedicine for Intranasal Delivery to Improve Brain Uptake

Volume: 15   Issue: 4
Pp: 461-469
Amit A. Patel*, Ravish J. Patel* and Shachi R. Patel
DOI: 10.2174/1567201814666171013150534

Impact of Surfactants on Skin Penetration of Dexpanthenol

Volume: 15   Issue: 3
Pp: 351-356
Flavia Laffleur*, Stefan Pschick, Jan Barthelmes, Sabine Hauptstein and Andreas Bernkop-Schnurch
DOI: 10.2174/1567201814666170503142707

Nanofibers: An Effective Tool for Controlled and Sustained Drug Delivery

Volume: 15   Issue: 2
Pp: 155-166
Amandeep Singh, Goutam Rath, Ranjit Singh and Amit K Goyal*
DOI: 10.2174/1567201814666171002115230

Development and Evaluation of High Bioavailable Sustained-Release Nimodipine Tablets Prepared with Monolithic Osmotic Pump Technology

Volume: 15   Issue: 1
Pp: 44-51
Hua Kong, Fanglin Yu, Yan Liu, Yang Yang, Mingyuan Li, Xiaohui Cheng, Xiaoqin Hu, Xuemei Tang, Zhiping Li* and Xingguo Mei
DOI: 10.2174/1567201814666161109122840

Functionalized Carbon Nano-scale Drug Delivery Systems From Biowaste Sago Bark For Cancer Cell Imaging

Volume: 14   Issue: 8
Pp: 1071-1077
Shoriya Aruni Abdul Manaf, Gurumurthy Hegde, Uttam Kumar Mandal, Wong Tin Wui and Partha Roy*
DOI: 10.2174/1567201813666161017130612

Role of Nanoparticles in Drug Delivery and Regenerative Therapy for Bone Diseases

Volume: 14   Issue: 7
Pp: 904-916
Sonia Gera, Sunitha Sampathi* and Sujatha Dodoala
DOI: 10.2174/1567201813666161230142123

PD-1/PD-Ls: A New Target for Regulating Immunopathogenesis in Central Nervous System Disorders

Volume: 14   Issue: 6
Pp: 791-796
Jie Wu, Zhengquan Yu and Gang Chen*
DOI: 10.2174/1567201814666161123152311

Ethosomes and Transfersomes: Principles, Perspectives and Practices

Volume: 14   Issue: 5
Pp: 613-633
Varun Garg, Harmanpreet Singh, Sneha Bimbrawh, Sachin Kumar Singh*, Monica Gulati, Yogyata Vaidya and Prabhjot Kaur
DOI: 10.2174/1567201813666160520114436

Preparation and Optimization of Amorphous Ursodeoxycholic Acid Nano-suspensions by Nanoprecipitation based on Acid-base Neutralization for Enhanced Dissolution

Volume: 14   Issue: 4
Pp: 483-491
Yike Xie, Zhongjian Chen, Rui Su, Ye Li, Jianping Qi, Wei Wu and Yi Lu*
DOI: 10.2174/1567201813666160902152122

Chitosan Functionalized CuS Nanoparticles Boots Gene Transfection via Photothermal Effect

Volume: 14   Issue: 3
Pp: 334-341
Li Lin, Xiaoda Li, Yongbo Yang, Lijia Jing, Xiuli Yue, Xuzhu Chen and Zhifei Dai
DOI: 10.2174/1567201813666160108114430

Evaluation of Eudragit® Retard Polymers for the Microencapsulation of Alpha-Lipoic Acid open access plus

Volume: 13   Issue: 7
Pp: 1165-1175
Tiziana M.G. Pecora, Teresa Musumeci, Lucrezia Musumeci, Massimo Fresta and Rosario Pignatello
DOI: 10.2174/1567201812666151016095342

Hesperetin Liposomes for Cancer Therapy

Volume: 13   Issue: 5
Pp: 711-719
Joy Wolfram, Bronwyn Scott, Kathryn Boom, Jianliang Shen, Carlotta Borsoi, Krishna Suri, Rossella Grande, Massimo Fresta, Christian Celia, Yuliang Zhao, Haifa Shen and Mauro Ferrari
DOI: 10.2174/1567201812666151027142412

Oral Mucosa for Delivery of Drugs, Allergens and Vaccines: Where are we Now?

Volume: 13   Issue: 2
Pp: 172-174
Sevda Senel
DOI: 10.2174/156720181302160427000605

In vitro Percutaneous Absorption of Niacinamide and Phytosterols and in vivo Evaluation of their Effect on Skin Barrier Recovery promotion: free to download

Volume: 13   Issue: 1
Pp: 111-120
Alessia Offerta, Francesco Bonina, Franco Gasparri, Andrea Zanardi, Lucia Micicchè and Carmelo Puglia
DOI: 10.2174/1567201812666150722123218

Improving Protein Stability and Controlling Protein Release by Adding Poly (Cyclohexane -1, 4 -Diyl Acetone Dimethylene Ketal) to PLGA Microspheres

Volume: 12   Issue: 6
Pp: 726-735
Chenhui Wang, Changhui Yu, Kongtong Yu, Lesheng Teng, Jiaxin Liu, Xuesong Wang, Fengying Sun and Youxin Li
DOI: 10.2174/1567201812666150316112635

Physically Cross-linked Hydrogels of β -cyclodextrin Polymer and Poly(ethylene glycol)-cholesterol as Delivery Systems for Macromolecules and Small Drug Molecules

Volume: 12   Issue: 4
Pp: 415-424
Shaaban K. Osman, Ghareb M. Soliman and Saleh Abd El Rasoul
DOI: 10.2174/1567201812666150326113331

The Role of Tomatine Adjuvant in Antigen Delivery for Cross- Presentation

Volume: 12   Issue: 3
Pp: 342-350
Paul Y.-J. Hsu, Ching-An Wu, Shan-Shan Shen and Ya-Wun Yang
DOI: 10.2174/1567201812666141210114747

Stability Studies on Piroxicam Encapsulated Niosomes

Volume: 12   Issue: 2
Pp: 192-199
Zehra Ceren Ertekin, Zerrin Sezgin Bayindir and Nilufer Yuksel
DOI: 10.2174/1567201811666140723115852

Self-Adjuvanting Therapeutic Peptide-Based Vaccine Induce CD8⁺ Cytotoxic T Lymphocyte Responses in a Murine Human Papillomavirus Tumor Model promotion: free to download

Volume: 12   Issue: 1
Pp: 3-8
Tzu-Yu Liu, Ashwini Kumar Giddam, Waleed M. Hussein, Zhongfan Jia, Nigel A.J. McMillan, Michael J. Monteiro, Istvan Toth and Mariusz Skwarczynski
DOI: 10.2174/1567201811666141001155729

Nanotechnology in Dentistry: Drug Delivery Systems for the Control of Biofilm-Dependent Oral Diseases

Volume: 11   Issue: 6
Pp: 719-728
Francisco Fabio Oliveira de Sousa, Camila Ferraz, Lidiany K arla de Azevedo Rodrigues, Jacqueline de Santiago Nojosa and Monica Yamauti
DOI: 10.2174/156720181106141202115157

Influence of Gold Nanoparticle Tagged Snake Venom Protein Toxin NKCT1 on Ehrlich Ascites Carcinoma (EAC) and EAC Induced Solid Tumor Bearing Male Albino Mice

Volume: 11   Issue: 5
Pp: 652-664
Tanmoy Bhowmik, Partha Pratim Saha, Anjan Kumar DasGupta and Antony Gomes
DOI: 10.2174/1567201811666140515101130

Co-precipitation of Tobramycin into Biomimetically Coated Orthopedic Fixation Pins Employing Submicron-Thin Seed Layers of Hydroxyapatite

Volume: 11   Issue: 4
Pp: 501-510
Jan H. Sorensen, Mirjam Lilja, Maria Astrand, Torben C. Sorensen, Philip Procter, Maria Stromme and Hartwig Steckel
DOI: 10.2174/1567201811666140311154104