Current Drug Metabolism

Decoding Novel Mechanisms and Emerging Therapeutic Strategies in Breast Cancer Resistance

Volume:21   Issue:3
Pp: 199-210
Sadat Shafi, Sana Khan, Farazul Hoda, Faizana Fayaz, Archu Singh, Mohammad Ahmed Khan*, Ruhi Ali, Faheem Hyder Pottoo, Sana Tariq and Abul Kalam Najmi
DOI: 10.2174/1389200221666200303124946

Dietary Baicalin Zinc Supplementation Alleviates Oxidative Stress and Enhances Nutrition Absorption in Deoxynivalenol Challenged Pigs

Volume:21   Issue:8
Pp: 614-625
Andong Zha, Zhijuan Cui, Ming Qi, Simeng Liao, Lixin Chen, Peng Liao* and Bie Tan*
DOI: 10.2174/1389200221666200302124102

Stem Cells in Tumour Microenvironment Aid in Prolonged Survival Rate of Cancer Cells and Developed Drug Resistance: Major Challenge in Osteosarcoma Treatment

Volume:21   Issue:1
Pp: 44-52
Bhaskar Birru, ChandraSai Potla Durthi*, Santhosh Kacham, Madhuri Pola, Satish Babu Rajulapati, Sreenivasa Rao Parcha and Mohammad Amjad Kamal
DOI: 10.2174/1389200221666200214120226

Nanostructured Lipid Carriers (NLCs): Nose-to-Brain Delivery and Theranostic Application

Volume:21   Issue:14
Pp: 1136-1143
Javed Ahmad*, Md. Rizwanullah, Saima Amin, Musarrat Husain Warsi, Mohammad Zaki Ahmad and Md. Abul Barkat
DOI: 10.2174/1389200221666200719003304

The Current State of Potential Therapeutic Modalities for Glioblastoma Multiforme: A Clinical Review

Volume:21   Issue:8
Pp: 564-578
Elmira Mohtashami, Negar Shafaei-Bajestani, Hamid Mollazadeh, Seyed Hadi Mousavi, Mohammad Jalili-Nik, Amirhossein Sahebkar* and Amir R. Afshari*
DOI: 10.2174/1389200221666200714101038

Chemical Metabolism of Xenobiotics by Gut Microbiota

Volume:21   Issue:4
Pp: 260-269
Radislav Nakov* and Tsvetelina Velikova
DOI: 10.2174/1389200221666200303113830

Prognostic Role of Hedgehog-GLI1 Signaling Pathway in Aggressive and Metastatic Breast Cancers

Volume:21   Issue:1
Pp: 33-43
Prasuja Rokkam, Shailender Gugalavath, Deepak Kakara Gift Kumar, Rahul Kumar Vempati and Rama Rao Malla*
DOI: 10.2174/1389200221666200122120625

Versatile and Valuable Utilization of Amidohydrolase L-glutaminase in Pharma and Food industries: A Review

Volume:21   Issue:1
Pp: 11-24
Chandrasai Potla Durthi*, Madhuri Pola, Satish Babu Rajulapati*, Anand Kishore Kola and Mohammad Amjad Kamal
DOI: 10.2174/1574884715666200116110542

Talin: A Potential Drug Target for Cancer Therapy

Volume:21   Issue:1
Pp: 25-32
Rama Rao Malla and Rahul Kumar Vempati *
DOI: 10.2174/1389200221666200214114018

Using Reduced Amino Acid Alphabet and Biological Properties to Analyze and Predict Animal Neurotoxin Protein

Volume:21   Issue:10
Pp: 810-817
Yao Yu, Shiyuan Wang, Yakun Wang, Yiyin Cao, Chunlu Yu, Yi Pan, Dongqing Su, Qianzi Lu, Yongchun Zuo* and Lei Yang*
DOI: 10.2174/1389200221666200520090555

Applications of Machine Learning in Drug Target Discovery

Volume:21   Issue:10
Pp: 790-803
Dongrui Gao, Qingyuan Chen, Yuanqi Zeng, Meng Jiang and Yongqing Zhang*
DOI: 10.2174/1567201817999200728142023

Lipid Nanoformulations in the Treatment of Neuropsychiatric Diseases: An Approach to Overcome the Blood Brain Barrier

Volume:21   Issue:9
Pp: 674-684
Saleha Rehman, Bushra Nabi, Faheem Hyder Pottoo, Sanjula Baboota and Javed Ali*
DOI: 10.2174/1573399816666200627214129

2020 FDA Drug-drug Interaction Guidance: A Comparison Analysis and Action Plan by Pharmaceutical Industrial Scientists

Volume:21   Issue:6
Pp: 403-426
Sirimas Sudsakorn, Praveen Bahadduri, Jennifer Fretland and Chuang Lu*
DOI: 10.2174/1389200221666200620210522

Exosome-based Tumor Therapy: Opportunities and Challenges

Volume:21   Issue:5
Pp: 339-351
Chunmei Li, Xiaoming Hou, Peng Zhang, Juan Li, Xiaoguang Liu, Yuping Wang, Quanlin Guan and Yongning Zhou*
DOI: 10.2174/1389200221666200515103354

Preclinical Study of the Pharmacokinetics of p75ECD-Fc, a Novel Human Recombinant Protein for Treatment of Alzheimer’s Disease, in Sprague Dawley Rats

Volume:21   Issue:3
Pp: 235-244
Sally Kelliny, Ho Yin Lam, Ankit Parikh, Yan-Jiang Wang, Larisa Bobrovskaya, Richard Upton and Xin-Fu Zhou*
DOI: 10.2174/1389200221666200502015203

Natural Compounds as Source of Aldose Reductase (AR) Inhibitors for the Treatment of Diabetic Complications: A Mini Review

Volume:21   Issue:14
Pp: 1091-1116
Ajmer Singh Grewal, Komal Thapa, Neha Kanojia, Neelam Sharma and Sukhbir Singh*
DOI: 10.2174/1389200221666201016124125

Germacrone: A Potent Secondary Metabolite with Therapeutic Potential in Metabolic Diseases, Cancer and Viral Infections

Volume:21   Issue:14
Pp: 1079-1090
Ammara Riaz, Azhar Rasul*, Nazia Kanwal, Ghulam Hussain, Muhammad Ajmal Shah*, Iqra Sarfraz, Rubab Ishfaq, Rabia Batool, Fariha Rukhsar and Şevki Adem
DOI: 10.2174/1389200221999200728144801

Recent Advances in Treatment of Childhood Obesity

Volume:21   Issue:14
Pp: 1072-1078
Walter Milano, Paola Ambrosio, Francesca Carizzone, Walter Di Munzio, Valeria De Biasio and Anna Capasso*
DOI: 10.2174/1389200221666200817112311

A Review: Effects of Macrolides on CYP450 Enzymes

Volume:21   Issue:12
Pp: 928-937
Liyun Zhang, Xiaoqing Xu, Sara Badawy, Awais Ihsan, Zhenli Liu, Changqing Xie, Xu Wang* and Yanfei Tao*
DOI: 10.2174/1389200221666200817113920

The Metabolism and Pharmacokinetics of Rhein and Aurantio-Obtusin

Volume:21   Issue:12
Pp: 960-968
Shun-Li Xiao, Liang-Jun Guan, Ren-Feng Jiang, Xiang-Gen Wang, Xing Li and Wei Cai*
DOI: 10.2174/1389200221666200719002128

Role of Glucose Transporters in Drug Membrane Transport

Volume:21   Issue:12
Pp: 947-958
Xin Wang, Kunkun Guo, Baolin Huang, Zimin Lin and Zheng Cai*
DOI: 10.2174/1389200221666200810125924

Research Progress of Herbal Medicines on Drug Metabolizing Enzymes: Consideration Based on Toxicology

Volume:21   Issue:12
Pp: 913-927
Shuting Wang, Wanfang Li, Jianbo Yang, Zengyan Yang, Cuiping Yang* and Hongtao Jin*
DOI: 10.2174/1389200221999200819144204

Study on the Plasma Protein Binding Rate and Compatibility Regularity of the Constituents Migrating to Blood of Simiao Yong’an Decoction

Volume:21   Issue:12
Pp: 979-993
Xiao Yu, Qishu Jiao, Yanyan Jiang, Shuzhen Guo, Wei Zhang* and Bin Liu*
DOI: 10.2174/1567201817666200731170731

The Influence of Different Disease States on Rituximab Pharmacokinetics

Volume:21   Issue:12
Pp: 938-946
Xiaoxing Wang, Wenwen Du, Xianglin Zhang* and Pengmei Li*
DOI: 10.2174/1389200221666200719004035

The Current Application of LC-MS/MS in Pharmacokinetics of Traditional Chinese Medicines (Recent Three Years): A Systematic Review

Volume:21   Issue:12
Pp: 969-978
Yang Wang, Lu Zhang, Shuang Gu, Zhaorui Yin, Zhe Shi, Ping Wang* and Changhua Xu*
DOI: 10.2174/1389200221666201009142418