Current Drug Metabolism

Decoding Novel Mechanisms and Emerging Therapeutic Strategies in Breast Cancer Resistance

Volume:21   Issue:3
Pp: 199-210
Sadat Shafi, Sana Khan, Farazul Hoda, Faizana Fayaz, Archu Singh, Mohammad Ahmed Khan*, Ruhi Ali, Faheem Hyder Pottoo, Sana Tariq and Abul Kalam Najmi
DOI: 10.2174/1389200221666200303124946

Dietary Baicalin Zinc Supplementation Alleviates Oxidative Stress and Enhances Nutrition Absorption in Deoxynivalenol Challenged Pigs

Volume:21   Issue:8
Pp: 614-625
Andong Zha, Zhijuan Cui, Ming Qi, Simeng Liao, Lixin Chen, Peng Liao* and Bie Tan*
DOI: 10.2174/1389200221666200302124102

The Current State of Potential Therapeutic Modalities for Glioblastoma Multiforme: A Clinical Review

Volume:21   Issue:8
Pp: 564-578
Elmira Mohtashami, Negar Shafaei-Bajestani, Hamid Mollazadeh, Seyed Hadi Mousavi, Mohammad Jalili-Nik, Amirhossein Sahebkar* and Amir R. Afshari*
DOI: 10.2174/1389200221666200714101038

2020 FDA Drug-drug Interaction Guidance: A Comparison Analysis and Action Plan by Pharmaceutical Industrial Scientists

Volume:21   Issue:6
Pp: 403-426
Sirimas Sudsakorn, Praveen Bahadduri, Jennifer Fretland and Chuang Lu*
DOI: 10.2174/1389200221666200620210522

Stem Cells in Tumour Microenvironment Aid in Prolonged Survival Rate of Cancer Cells and Developed Drug Resistance: Major Challenge in Osteosarcoma Treatment

Volume:21   Issue:1
Pp: 44-52
Bhaskar Birru, ChandraSai Potla Durthi*, Santhosh Kacham, Madhuri Pola, Satish Babu Rajulapati, Sreenivasa Rao Parcha and Mohammad Amjad Kamal
DOI: 10.2174/1389200221666200214120226

Modulation of the Drug Resistance by Platonia insignis Mart. Extract, Ethyl Acetate Fraction and Morelloflavone/Volkensiflavone (Biflavonoids) in Staphylococcus aureus Strains Overexpressing Efflux Pump Genes

Volume:22   Issue:2
Pp: 114-122
Andressa K.F. e Silva, Antonielly C. dos Reis, Emanuelly E.A. Pinheiro, Jonas N. de Sousa, Felipe A. de Alcântara Oliveira, Arkellau K.S. Moura, José de Sousa L. Neto, Antonia M. das Graças L. Citó, José P. Siqueira-Júnior, Glenn W. Kaatz and Humberto M. Barreto*
DOI: 10.2174/1389200221666200523155617

Nanostructured Lipid Carriers (NLCs): Nose-to-Brain Delivery and Theranostic Application

Volume:21   Issue:14
Pp: 1136-1143
Javed Ahmad*, Md. Rizwanullah, Saima Amin, Musarrat Husain Warsi, Mohammad Zaki Ahmad and Md. Abul Barkat
DOI: 10.2174/1389200221666200719003304

Research Progress of Herbal Medicines on Drug Metabolizing Enzymes: Consideration Based on Toxicology

Volume:21   Issue:12
Pp: 913-927
Shuting Wang, Wanfang Li, Jianbo Yang, Zengyan Yang, Cuiping Yang* and Hongtao Jin*
DOI: 10.2174/1389200221999200819144204

Chemical Metabolism of Xenobiotics by Gut Microbiota

Volume:21   Issue:4
Pp: 260-269
Radislav Nakov* and Tsvetelina Velikova
DOI: 10.2174/1389200221666200303113830

Prognostic Role of Hedgehog-GLI1 Signaling Pathway in Aggressive and Metastatic Breast Cancers

Volume:21   Issue:1
Pp: 33-43
Prasuja Rokkam, Shailender Gugalavath, Deepak Kakara Gift Kumar, Rahul Kumar Vempati and Rama Rao Malla*
DOI: 10.2174/1389200221666200122120625

Versatile and Valuable Utilization of Amidohydrolase L-glutaminase in Pharma and Food industries: A Review

Volume:21   Issue:1
Pp: 11-24
Chandrasai Potla Durthi*, Madhuri Pola, Satish Babu Rajulapati*, Anand Kishore Kola and Mohammad Amjad Kamal
DOI: 10.2174/1574884715666200116110542

Talin: A Potential Drug Target for Cancer Therapy

Volume:21   Issue:1
Pp: 25-32
Rama Rao Malla and Rahul Kumar Vempati *
DOI: 10.2174/1389200221666200214114018

Natural Compounds as Source of Aldose Reductase (AR) Inhibitors for the Treatment of Diabetic Complications: A Mini Review

Volume:21   Issue:14
Pp: 1091-1116
Ajmer Singh Grewal, Komal Thapa, Neha Kanojia, Neelam Sharma and Sukhbir Singh*
DOI: 10.2174/1389200221666201016124125

Metabolism and Interactions of Chloroquine and Hydroxychloroquine with Human Cytochrome P450 Enzymes and Drug Transporters

Volume:21   Issue:14
Pp: 1127-1135
Slobodan Rendic* and Frederick Peter Guengerich
DOI: 10.2174/1389200221999201208211537

A Review: Effects of Macrolides on CYP450 Enzymes

Volume:21   Issue:12
Pp: 928-937
Liyun Zhang, Xiaoqing Xu, Sara Badawy, Awais Ihsan, Zhenli Liu, Changqing Xie, Xu Wang* and Yanfei Tao*
DOI: 10.2174/1389200221666200817113920

The Metabolism and Pharmacokinetics of Rhein and Aurantio-Obtusin

Volume:21   Issue:12
Pp: 960-968
Shun-Li Xiao, Liang-Jun Guan, Ren-Feng Jiang, Xiang-Gen Wang, Xing Li and Wei Cai*
DOI: 10.2174/1389200221666200719002128

Role of Glucose Transporters in Drug Membrane Transport

Volume:21   Issue:12
Pp: 947-958
Xin Wang, Kunkun Guo, Baolin Huang, Zimin Lin and Zheng Cai*
DOI: 10.2174/1389200221666200810125924

The Influence of Different Disease States on Rituximab Pharmacokinetics

Volume:21   Issue:12
Pp: 938-946
Xiaoxing Wang, Wenwen Du, Xianglin Zhang* and Pengmei Li*
DOI: 10.2174/1389200221666200719004035

Using Reduced Amino Acid Alphabet and Biological Properties to Analyze and Predict Animal Neurotoxin Protein

Volume:21   Issue:10
Pp: 810-817
Yao Yu, Shiyuan Wang, Yakun Wang, Yiyin Cao, Chunlu Yu, Yi Pan, Dongqing Su, Qianzi Lu, Yongchun Zuo* and Lei Yang*
DOI: 10.2174/1389200221666200520090555

Applications of Machine Learning in Drug Target Discovery

Volume:21   Issue:10
Pp: 790-803
Dongrui Gao, Qingyuan Chen, Yuanqi Zeng, Meng Jiang and Yongqing Zhang*
DOI: 10.2174/1567201817999200728142023

Lipid Nanoformulations in the Treatment of Neuropsychiatric Diseases: An Approach to Overcome the Blood Brain Barrier

Volume:21   Issue:9
Pp: 674-684
Saleha Rehman, Bushra Nabi, Faheem Hyder Pottoo, Sanjula Baboota and Javed Ali*
DOI: 10.2174/1573399816666200627214129

Absorption, Metabolism and Excretion of Surufatinib in Rats and Humans

Volume:21   Issue:5
Pp: 357-367
Ke Li, Sheng Ma, Liyan Miao*, Songhua Fan, Bin Pan, Weihan Zhang, Weiguo Su, Yating Xiong, Zheming Gu, Lian Guo and Yang Sai*
DOI: 10.2174/1389200221666200514131721

The Potential Role of Serum Exosomes in Preeclampsia

Volume:21   Issue:5
Pp: 352-356
Xuelin Gao, Lulu Shao, Xinying Ge, Long Zhang , Dexin Chen and Rongxia He*
DOI: 10.2174/1389200221666200525152441

Exosome-based Tumor Therapy: Opportunities and Challenges

Volume:21   Issue:5
Pp: 339-351
Chunmei Li, Xiaoming Hou, Peng Zhang, Juan Li, Xiaoguang Liu, Yuping Wang, Quanlin Guan and Yongning Zhou*
DOI: 10.2174/1389200221666200515103354

Preclinical Study of the Pharmacokinetics of p75ECD-Fc, a Novel Human Recombinant Protein for Treatment of Alzheimer’s Disease, in Sprague Dawley Rats

Volume:21   Issue:3
Pp: 235-244
Sally Kelliny, Ho Yin Lam, Ankit Parikh, Yan-Jiang Wang, Larisa Bobrovskaya, Richard Upton and Xin-Fu Zhou*
DOI: 10.2174/1389200221666200502015203