Current Drug Metabolism

2020 FDA Drug-drug Interaction Guidance: A Comparison Analysis and Action Plan by Pharmaceutical Industrial Scientists

Volume: 21   Issue: 6
Pp: 403-426
Sirimas Sudsakorn, Praveen Bahadduri, Jennifer Fretland and Chuang Lu*
DOI: 10.2174/1389200221666200620210522

Stem Cells in Tumour Microenvironment Aid in Prolonged Survival Rate of Cancer Cells and Developed Drug Resistance: Major Challenge in Osteosarcoma Treatment

Volume: 21   Issue: 1
Pp: 44-52
Bhaskar Birru, ChandraSai Potla Durthi*, Santhosh Kacham, Madhuri Pola, Satish Babu Rajulapati, Sreenivasa Rao Parcha and Mohammad Amjad Kamal
DOI: 10.2174/1389200221666200214120226

A Review: Effects of Macrolides on CYP450 Enzymes

Volume: 21   Issue: 12
Pp: 928-937
Liyun Zhang, Xiaoqing Xu, Sara Badawy, Awais Ihsan, Zhenli Liu, Changqing Xie, Xu Wang* and Yanfei Tao*
DOI: 10.2174/1389200221666200817113920

Current Treatment Options for HCC: From Pharmacokinetics to Efficacy and Adverse Events in Liver Cirrhosis

Volume: 21   Issue: 11
Pp: 866-884
Giovanni Galati*, Antonio Fabio Massimo Vainieri*, Claudia Angela Maria Fulgenzi, Stefano Di Donato, Marianna Silletta, Paolo Gallo, Angelo Onorato, Umberto Vespasiani-Gentilucci and Antonio Picardi
DOI: 10.2174/1389200221999200918141239

Model-based Meta-analysis to Compare Primary Efficacy-endpoint, Efficacy-time Course, Safety, and Tolerability of Opioids Used in the Management of Osteoarthritic Pain in Humans

Volume: 21   Issue: 5
Pp: 390-399
Suhaila Omar Alhaj-Suliman, Gary Milavetz and Aliasger Karimjee Salem*
DOI: 10.2174/1389200221666200514130441

Role of Exosomes in the Exchange of Spermatozoa after Leaving the Seminiferous Tubule: A Review

Volume: 21   Issue: 5
Pp: 330-338
Luming Wu, Yuan Ding, Shiqiang Han and Yiqing Wang*
DOI: 10.2174/1389200221666200520091511

Changes of Transporters and Drug-metabolizing Enzymes in Nephrotic Syndrome

Volume: 21   Issue: 5
Pp: 368-378
Yaqian Dong, Linna Gong, Xianyuan Lu, Mingguang Ye, Yu Lin, Shuting Xie, Jiaxing Zhang, Fenghua Zhou, Lan Tang, Wei Zou* and Menghua Liu*
DOI: 10.2174/1389200221666200512113731

Toward Greater Insights on Applications of Modeling and Simulation in Pregnancy

Volume: 21   Issue: 9
Pp: 722-741
Ling Song, Cheng Cui, Ying Zhou, Zhongqi Dong, Zhiheng Yu, Yifan Xu, Tianyan Zhou, Khaled Abduljalil, Hongcan Han, Li Li, Jinbo Yang, Yangyu Zhao*, Haiyan Li and Dongyang Liu*
DOI: 10.2174/1389200221666200907143941

Updates on the Pharmacology of Chloroquine against Coronavirus Disease 2019 (COVID-19): A Perspective on its Use in the General and Geriatric Population

Volume: 21   Issue: 7
Pp: 534-540
Xueting Yao*, Zhe Hou*, Cheng Cui, Miao Zhang, Siqi Tu, Haiyan Li and Dongyang Liu*
DOI: 10.2174/1389200221666200711160440

Comparison between Atorvastatin and Rosuvastatin on Secondary Percutaneous Coronary Intervention Rate and the Risk Factors in Patients with Coronary Heart Disease

Volume: 21   Issue: 10
Pp: 818-828
Jie Zhang, Jiaqi Wang, Han Yu, Guanghua Wang, Junfang Zhang, Rui Zhu*, Xuebo Liu* and Jue Li*
DOI: 10.2174/1389200221666200310110410

The Metabolism and Pharmacokinetics of Rhein and Aurantio-Obtusin

Volume: 21   Issue: 12
Pp: 960-968
Shun-Li Xiao, Liang-Jun Guan, Ren-Feng Jiang, Xiang-Gen Wang, Xing Li and Wei Cai*
DOI: 10.2174/1389200221666200719002128

Biosurfactants as a Novel Additive in Pharmaceutical Formulations: Current Trends and Future Implications

Volume: 21   Issue: 11
Pp: 885-901
Shubham Thakur, Amrinder Singh, Ritika Sharma, Rohan Aurora and Subheet Kumar Jain*
DOI: 10.2174/1389200221666201008143238

Review on the Clinical Pharmacology of Hydroxychloroquine Sulfate for the Treatment of COVID-19

Volume: 21   Issue: 6
Pp: 427-435
Cheng Cui, Siqi Tu, Valerie Sia Jie En, Xiaobei Li, Xueting Yao, Haiyan Li* and Dongyang Liu*
DOI: 10.2174/1389200221666200610172929

Further Considerations Towards an Effective and Efficient Oncology Drug Discovery DMPK Strategy

Volume: 21   Issue: 2
Pp: 145-162
Beth Williamson , Nicola Colclough, Adrian John Fretland, Barry Christopher Jones, Rhys Dafydd Owen Jones and Dermot Francis McGinnity *
DOI: 10.2174/1389200221666200312104837

Prognostic Role of Hedgehog-GLI1 Signaling Pathway in Aggressive and Metastatic Breast Cancers

Volume: 21   Issue: 1
Pp: 33-43
Prasuja Rokkam, Shailender Gugalavath, Deepak Kakara Gift Kumar, Rahul Kumar Vempati and Rama Rao Malla*
DOI: 10.2174/1389200221666200122120625

The Potential Role of Serum Exosomes in Preeclampsia

Volume: 21   Issue: 5
Pp: 352-356
Xuelin Gao, Lulu Shao, Xinying Ge, Long Zhang , Dexin Chen and Rongxia He*
DOI: 10.2174/1389200221666200525152441

New Ultra Low Volume Bowel Preparation and Overview of Existing Bowel Preparations

Volume: 21   Issue: 11
Pp: 844-849
Hein Htet* and Jonathan Segal
DOI: 10.2174/1567201817666200810112136

The Influence of Different Disease States on Rituximab Pharmacokinetics

Volume: 21   Issue: 12
Pp: 938-946
Xiaoxing Wang, Wenwen Du, Xianglin Zhang* and Pengmei Li*
DOI: 10.2174/1389200221666200719004035

The Current Application of LC-MS/MS in Pharmacokinetics of Traditional Chinese Medicines (Recent Three Years): A Systematic Review

Volume: 21   Issue: 12
Pp: 969-978
Yang Wang, Lu Zhang, Shuang Gu, Zhaorui Yin, Zhe Shi, Ping Wang* and Changhua Xu*
DOI: 10.2174/1389200221666201009142418

Metabolism and Interactions of Chloroquine and Hydroxychloroquine with Human Cytochrome P450 Enzymes and Drug Transporters

Volume: 21   Issue: 14
Pp: 1127-1135
Slobodan Rendic* and Frederick Peter Guengerich
DOI: 10.2174/1389200221999201208211537