Current Drug Metabolism


Ming Hu
University of Houston
College of Pharmacy
Houston, TX

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Editorial [Hot Topic: High Throughput In Vitro ADME/Tox Profiling for Drug Discovery(Guest Editor: Edward H. Kerns)] promotion: free to download

Volume:9   Issue: 9
Pp: 845-846
Edward H. Kerns
DOI: 10.2174/138920008786485074

High Throughput ADME Screening: Practical Considerations, Impact on the Portfolio and Enabler of In Silico ADME Models

Volume:9   Issue: 9
Pp: 847-853
Cornelis E.C.A. Hop, Mark J. Cole, Ralph E. Davidson, David B. Duignan, James Federico, John S. Janiszewski, Kelly Jenkins, Suzanne Krueger, Rebecca Lebowitz, Theodore E. Liston, Walter Mitchell, Mark Snyder, Stefan J. Steyn, John R. Soglia, Christine Taylor, Matt D. Troutman, John Umland, Michael West, Kevin M. Whalen, Veronica Zelesky and Sabrina X. Zhao
DOI: 10.2174/138920008786485092

Plasma / Serum Protein Binding Determinations

Volume:9   Issue: 9
Pp: 854-859
Michael J. Banker and Tracey H. Clark
DOI: 10.2174/138920008786485065

Solution Stability - Plasma, Gastrointestinal, Bioassay

Volume:9   Issue: 9
Pp: 860-868
Li Di and Edward H. Kerns
DOI: 10.2174/138920008786485218

In Vitro Solubility Assays in Drug Discovery

Volume:9   Issue: 9
Pp: 879-885
Edward H. Kerns, Li Di and Guy T. Carter
DOI: 10.2174/138920008786485100

Artificial Membrane Assays to Assess Permeability

Volume:9   Issue: 9
Pp: 886-892
Bernard Faller
DOI: 10.2174/138920008786485227

Permeability for Intestinal Absorption: Caco-2 Assay and Related Issues

Volume:9   Issue: 9
Pp: 893-900
Barry Press and Deanna Di Grandi
DOI: 10.2174/138920008786485119

Assays to Predict Drug Permeation Across the Blood-Brain Barrier, and Distribution to Brain

Volume:9   Issue: 9
Pp: 901-910
N. J. Abbott, D. E.M. Dolman and A. K. Patabendige
DOI: 10.2174/138920008786485182

In Vitro Cytochrome P450 Inhibition and Induction

Volume:9   Issue: 9
Pp: 928-939
Robert L. Walsky and Sherri E. Boldt
DOI: 10.2174/138920008786485128

Methods for Predicting In Vivo Pharmacokinetics Using Data from In Vitro Assays

Volume:9   Issue: 9
Pp: 940-951
J. Brian Houston and Aleksandra Galetin
DOI: 10.2174/138920008786485164

In Vitro Screening Techniques for Reactive Metabolites for Minimizing Bioactivation Potential in Drug Discovery

Volume:9   Issue: 9
Pp: 952-964
Chandra Prakash, Raman Sharma, Michelle Gleave and Angus Nedderman
DOI: 10.2174/138920008786485209

hERG (KCNH2 or Kv11.1) K+ Channels: Screening for Cardiac Arrhythmia Risk

Volume:9   Issue: 9
Pp: 965-970
Mark R. Bowlby, Ravi Peri, Howard Zhang and John Dunlop
DOI: 10.2174/138920008786485083

The Role of Genetic Toxicology in Drug Discovery and Optimization

Volume:9   Issue: 9
Pp: 978-985
L. L. Custer and K. S. Sweder
DOI: 10.2174/138920008786485191

Perspectives on Bioanalytical Mass Spectrometry and Automation in Drug Discovery

Volume:9   Issue: 9
Pp: 986-994
John S. Janiszewski, Theodore E. Liston and Mark J. Cole
DOI: 10.2174/138920008786485173