Current Drug Metabolism

Editor-in-Chief

Ming Hu
College of Pharmacy
University of Houston
Houston, TX
(USA)

Personal Subscription
Become EABM
Become Reviewer
Call for Editor
Volume: 14 Issue: 1, January 2012

Preface

Volume:14   Issue: 1
Pp: 1-1
Chandra Prakash
DOI: 10.2174/1389200211309010001
Published on: 07 December, 2012

Editorial [Hot Topic Non-Animal Models Used in Drug Discovery: Drug Absorption and Metabolism Guest Editor: Hélder A. Santos]

Volume:14   Issue: 1
Pp: 2-3
Helder A. Santos
DOI: 10.2174/1389200211309010002
Published on: 07 December, 2012

Models to Predict Intestinal Absorption of Therapeutic Peptides and Proteins

Volume:14   Issue: 1
Pp: 4-20
Filipa Antunes, Fernanda Andrade, Domingos Ferreira, Hanne Mørck Nielsen and Bruno Sarmento
DOI: 10.2174/1389200211309010004
Published on: 07 December, 2012

Do the Recommended Standards for In Vitro Biopharmaceutic Classification of Drug Permeability Meet the "Passive Transport" Criterion for Biowaivers?

Volume:14   Issue: 1
Pp: 21-27
Simon Zakelj, Katja Berginc, Robert Roskar, Bor Kraljic and Albin Kristl
DOI: 10.2174/1389200211309010021
Published on: 07 December, 2012

Improving Oral Absorption Via Drug-Loaded Nanocarriers: Absorption Mechanisms, Intestinal Models and Rational Fabrication

Volume:14   Issue: 1
Pp: 28-56
Mohammad-Ali Shahbazi and Helder A. Santos
DOI: 10.2174/1389200211309010028
Published on: 07 December, 2012

Why We Need Proper PBPK Models to Examine Intestine and Liver Oral Drug Absorption

Volume:14   Issue: 1
Pp: 57-79
Edwin C.Y. Chow and K. Sandy Pang
DOI: 10.2174/1389200211309010057
Published on: 07 December, 2012

Evaluation of the Physicochemical and Biopharmaceutical Properties of Fluoro-Indomethacin

Volume:14   Issue: 1
Pp: 80-89
Michela M. Mori, Anu J. Airaksinen, Jouni T. Hirvonen, Helder A. Santos and Carla M. Caramella
DOI: 10.2174/1389200211309010080
Published on: 07 December, 2012

The Mechanisms Responsible for Garlic - Drug Interactions and their In Vivo Relevance

Volume:14   Issue: 1
Pp: 90-101
Katja Berginc and Albin Kristl
DOI: 10.2174/1389200211309010090
Published on: 07 December, 2012

In Vitro Methods to Study the Interplay of Drug Metabolism and Efflux in the Intestine

Volume:14   Issue: 1
Pp: 102-111
Sanna Siissalo and Aki T. Heikkinen
DOI: 10.2174/1389200211309010102
Published on: 07 December, 2012

Precision-cut Intestinal Slices as In Vitro Tool for Studies on Drug Metabolism

Volume:14   Issue: 1
Pp: 112-119
Geny M.M. Groothuis and Inge A.M. de Graaf
DOI: 10.2174/1389200211309010112
Published on: 07 December, 2012

Hurdles with Using In Vitro Models to Predict Human Blood-brain Barrier Drug Permeability: A Special Focus on Transporters and Metabolizing Enzymes

Volume:14   Issue: 1
Pp: 120-136
Ramzi Shawahna, Xavier Decleves and Jean-Michel Scherrmann
DOI: 10.2174/1389200211309010120
Published on: 07 December, 2012

Function and Regulation of the Cyp2a5/CYP2A6 Genes in Response to Toxic Insults in the Liver

Volume:14   Issue: 1
Pp: 137-150
A’edah Abu-Bakar, Jukka Hakkola, Risto Juvonen, Minna Rahnasto-Rilla, Hannu Raunio and Matti A. Lang
DOI: 10.2174/1389200211309010137
Published on: 07 December, 2012

Metabolism of the Antituberculosis Drug Ethionamide

Volume:14   Issue: 1
Pp: 151-158
Nuno Vale, Paula Gomes and Helder A. Santos
DOI: 10.2174/1389200211309010151
Published on: 07 December, 2012