Current Drug Therapy

Topical Lipid Based Drug Delivery Systems for Skin Diseases: A Review

Volume: 15   Issue: 4
Pp: 283-298
Suresh Kumar Sahu, Rakesh Raj*, Pooja Mongia Raj and Ram Alpana
DOI: 10.2174/1574885513666181112153213

Pathophysiology and Management of Atopic Dermatitis: A Laconic Review open access plus

Volume: 15   Issue: 4
Pp: 335-350
Pravin Kumar*, Dinesh Kumar Sharma and Mahendra Singh Ashawat
DOI: 10.2174/1574885514666190828152316

Bilosomes: Superior Vesicular Carriers open access plus

Volume: 15   Issue: 4
Pp: 312-320
Pradnya Palekar-Shanbhag*, Supriya Lande, Riya Chandra and Drushti Rane
DOI: 10.2174/1574885514666190917145510

Current Strategies and Future Perspective for the Effective Treatment of Diabetic Retinopathy

Volume: 15   Issue: 4
Pp: 299-311
Deep Shikha Sharma, Sachin Kumar Singh, Divya Thakur, Arya K.R, Rubiya Khursheed and Sheetu Wadhwa*
DOI: 10.2174/1574885514666191007101007

Development of Cinnarizine Microballoons by Sequential Optimization and In Vivo Imaging by Gamma Scintigraphy

Volume: 15   Issue: 4
Pp: 369-380
Bijaya Ghosh*, Arka Chatterjee, Moumita Das Kirtania and Sankha Chattopadhyay
DOI: 10.2174/1574885514666191119105908

Celecoxib A Selective COX-2 Inhibitor Mitigates Fibrosis but not Pneumonitis Following Lung Irradiation: A Histopathological Study open access plus

Volume: 15   Issue: 4
Pp: 351-357
Rasoul Azmoonfar, Peyman Amini, Hana Saffar, Elahe Motevaseli, Ehsan Khodamoradi, Dheyauldeen Shabeeb, Ahmed Eleojo Musa and Masoud Najafi*
DOI: 10.2174/1574885514666191119124739

Beneficial Effects of Melatonin and Atorvastatin on Retinopathy in Streptozocin-induced Diabetic Rats open access plus

Volume: 15   Issue: 4
Pp: 396-403
Mansoor Shahriari, Saeed Mehrzadi, Masood Naseripour, Iman Fatemi, Azam Hosseinzadeh, Mozhgan Rezaei Kanavi and Habib Ghaznavi*
DOI: 10.2174/1574885514666191204104925

Spectral Investigations, Molecular Interactions and Electrochemical Studies of (2R)-(-) 2-(2, 6-dimethylphenylaminocarbonyl)-1-methyl piperidinium chloride open access plus

Volume: 15   Issue: 4
Pp: 358-368
J. Deva Anban, J.Sharmi Kumar, C. James and Sayantan Pradhan*
DOI: 10.2174/1574885514666191204150832

2', 4'-dihydroxy-3, 4-methylenedioxychalcone Activate Mitochondrial Apoptosis of Ehrlich Ascites Carcinoma Cells

Volume: 15   Issue: 4
Pp: 321-334
Mahbuba Khatun, Farhadul Islam*, Vinod Gopalan, Md. Motiar Rahman, Natasha Zuberi, Laboni Khatun, Md. Abdur Rakiba, Md. Azizul Islam, Alfred King-Yin Lam and Jahan Ara Khanam*
DOI: 10.2174/1574885514666191211122437

Hypoglycemic Hemiparesis Masquerading As Ischemic Stroke: When Guideline Fails

Volume: 15   Issue: 4
Pp: 420-422
Dhruvkumar M. Patel, Mukundkumar V. Patel *, Jayanti K. Gurumukhani, Maitri M. Patel, Himal J. Mahadevia and Ritesh A. Gajjar
DOI: 10.2174/1574885515666191227155624

The Effect of Treatment and Bone Metabolic Factors on Fracture Incidence in Patients with Thalassemia-Induced Osteoporosis: An Observational Study open access plus

Volume: 15   Issue: 4
Pp: 381-388
Athanasios N. Tsartsalis*, George I. Lambrou, Eugenia Vlachou, Athanasia Samartzi, George P. Chrousos, Christina Kanaka-Gantenbein and Antonis Kattamis
DOI: 10.2174/1574885515666200106110602

Evaluation of the Drug Utilization Pattern of Pre and Post Operative Medicines used in Surgical Department: A Prospective Observational Study

Volume: 15   Issue: 4
Pp: 389-395
Shikha Sharma and Anoop Kumar*
DOI: 10.2174/1574885515666200106111129

Allopurinol Loaded Transferosomes for the Alleviation of Symptomatic After-effects of Gout: An Account of Pharmaceutical Implications open access plus

Volume: 15   Issue: 4
Pp: 404-419
Ruchi Tiwari*, Gaurav Tiwari and Rachna Singh
DOI: 10.2174/1574885515666200120124214

PCR: An Effective, Faster and Relevant Method for the Detection of Clinical Isolates of Candida albicans

Volume: 15   Issue: 3
Pp: 216-218
Kamal Uddin Zaidi, Abin Mani*, Richa Parmar and Vijay Thawani
DOI: 10.2174/1574885514666190409104833

Oleic Acid Vesicles for Transdermal Delivery of Propranolol Hydrochloride: Development and Characterization open access plus

Volume: 15   Issue: 3
Pp: 238-248
Lalit Kumar and Puneet Utreja*
DOI: 10.2174/1574885514666190722164119

The Effect of Casein Kinase 2 Inhibition on three Leukemic Cell Lines

Volume: 15   Issue: 3
Pp: 209-215
Luka Horvat, Mariastefania Antica and Maja Matulić*
DOI: 10.2174/1574885514666190724111509

Network-Pharmacology and DFT Based Approach Towards Identification of Leads from Homalomena aromatica for Multi-Target In-Silico Screening on Entamoeba histolytica Proteins

Volume: 15   Issue: 3
Pp: 226-237
Ashis Kumar Goswami , Hemanta Kumar Sharma*, Neelutpal Gogoi and Bhaskar Jyoti Gogoi
DOI: 10.2174/1574885514666190801102336

Treatment with Cinacalcet in Hemodialysis Patients with Severe Secondary Hyperparathyroidism, Influences Bone Mineral Metabolism and Anemia Parameters

Volume: 15   Issue: 3
Pp: 249-263
Maria Aktsiali, Theodora Papachrysanthou , Ioannis Griveas, Christos Andriopoulos, Panagiotis Sitaras, Ioannis K. Triantafyllopoulos and George I. Lambrou*
DOI: 10.2174/1574885514666190802144629

Azelaic Acid: A Promising Agent for Dermatological Applications

Volume: 15   Issue: 3
Pp: 181-193
Anil Kumar, Rekha Rao* and Poonam Yadav
DOI: 10.2174/1574885514666190904160228

Formulation and Characterization of Solid Dispersion Containing Capsaicin for the Treatment of Diabetes

Volume: 15   Issue: 3
Pp: 219-225
Tapan Kumar Giri*, Payel Roy and Subhasis Maity
DOI: 10.2174/1574885514666190916152432

Prevention and Therapy of Prostate Cancer: An Update on Alternatives for Treatment and Future Perspectives

Volume: 15   Issue: 3
Pp: 168-180
Fernanda Majolo, Bruna Caye, Stefani Natali Stoll, Juliano Leipelt, Ana Lúcia Abujamra and Márcia Inês Goettert*
DOI: 10.2174/1574885514666190917150635

In Silico Docking, ADMET and QSAR Study of few Antimalarial Phytoconstituents as Inhibitors of Plasmepsin II of P. falciparum Against Malaria

Volume: 15   Issue: 3
Pp: 264-273
Syeda Sabiha Salam*, Pankaj Chetia and Devid Kardong
DOI: 10.2174/1574885514666190923112738

Effect of Canagliflozin, an SGLT2 Inhibitor, in Comparison with Atorvastatin on Dexamethasone-Induced Hepatic Steatosis in Albino Rats open access plus

Volume: 15   Issue: 3
Pp: 274-282
Eman I. Ahmed*, Amany M. Shaaban and Abdel Karim M. Abdel Latif
DOI: 10.2174/1574885514666191007094424

Traditional Herbal Medicines, Newer Herbs and Other Novel Approaches Integrated in Herbal Medicine for Atopic Dermatitis-A Narrative Review

Volume: 15   Issue: 3
Pp: 194-208
Pravin Kumar*, Dinesh Kumar Sharma* and Mahendra Singh Ashawat
DOI: 10.2174/1574885514666191018165209

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Volume: 15   Issue: 3
Pp: 167-167
Pradyumna Kumar Mishra
DOI: 10.2174/157488551503200622110526

Optimization and Quality by Design Approach for Piroxicam Fast Dissolving Tablet Formulations Using Box-Behnken Design

Volume: 15   Issue: 2
Pp: 152-165
Harekrishna Roy*, Sisir Nandi, Ungarala Pavani, Uppuluri Lakshmi, Tamma Saicharan Reddy and Damarla Venkata Sri Gayatri
DOI: 10.2174/1574885514666190409102614

Development and Characterization of Solid Dispersion System for Enhancing the Solubility and Dissolution Rate of Dietary Capsaicin

Volume: 15   Issue: 2
Pp: 143-151
Sumit Bera, Subhasis Maity, Balaram Ghosh, Animesh Ghosh and Tapan K. Giri*
DOI: 10.2174/1574885514666190724143351

An Updated Overview of The Complex Clinical Spectrum of Tourette Syndrome

Volume: 15   Issue: 2
Pp: 86-91
Natan Gadoth*
DOI: 10.2174/1574885514666191120143747

Drug and Non-drug Treatment of Tourette Syndrome

Volume: 15   Issue: 2
Pp: 132-142
Nathanel Zelnik*
DOI: 10.2174/1574885514666191121141923

Sleep and Sleep Disorders in Tourette Syndrome: What is Known and What is Still Unknown open access plus

Volume: 15   Issue: 2
Pp: 124-131
Arie Oksenberg*
DOI: 10.2174/1574885514666191121142555

The Pathophysiology of Tics; An Evolving Story

Volume: 15   Issue: 2
Pp: 92-123
Harvey S. Singer* and Farhan Augustine
DOI: 10.2174/1574885514666191121143930

The Many Faces of Tourette Syndrome promotion: free to download

Volume: 15   Issue: 2
Pp: 85-85
Natan Gadoth
DOI: 10.2174/157488551502200303113311

Investigation of the Role of the Alkalizing Agent in Sodium Alginate Liquid Anti-reflux Suspension

Volume: 15   Issue: 1
Pp: 53-60
Sangmesh Torne, A. Sheela* and N.C. Sarada
DOI: 10.2174/1574885514666190103140951

Optimization of Brinzolamide Loaded Microemulsion using Formulation by Design Approach: Characterization and In-vitro Evaluation

Volume: 15   Issue: 1
Pp: 37-52
Riyaz Gohil, Asha Patel*, Tosha Pandya and Abhay Dharamsi
DOI: 10.2174/1574885514666190104115802

Review on Preclinical and Clinical Evidence of Food (Beverages, Fruits and Vegetables) and Drug Interactions: Mechanism and Safety

Volume: 15   Issue: 1
Pp: 12-27
Yogesh C. Yadav*, Kamla Pathak and Devender Pathak
DOI: 10.2174/1574885514666190126141424

Formulation and in vitro Evaluation of Hesperidin-Phospholipid Complex and its Antioxidant Potential

Volume: 15   Issue: 1
Pp: 28-36
Bhupen Kalita* and Bhargab Nath Patwary
DOI: 10.2174/1574885514666190226155933

Effects of Coenzyme Q10 Supplementation on Serum Adiponectin Levels: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Volume: 15   Issue: 1
Pp: 3-11
Ali Nazary-Vannani, Ehsan Ghaedi, Shekoufeh Salamat, Afsaneh Sayyaf, Hamed K. Varkaneh, Hamed Mohammadi and Mahmoud Djalali*
DOI: 10.2174/1574885514666190308162322

Prevalence of Major Cardiac Events of Anthracycline-Induced Cardiotoxicity in Southwestern Iran: Different Response Patterns to Cumulative Dose

Volume: 15   Issue: 1
Pp: 78-84
Mahsa Behrouzian, Babak Najibi, Sabahat Haghi, Chehreh Mahdavi, Kaveh Jaseb* and Ehsan Ghaedi*
DOI: 10.2174/1574885514666190311145607

Polymeric Nanoparticles: A Promising Tool to Enhance the Solubility of Poorly Water Soluble Drug

Volume: 15   Issue: 1
Pp: 67-77
Nirmal M. Kasekar*, Sarabjit Singh, K.R. Jadhav and V.J. Kadam
DOI: 10.2174/1574885514666190610125127

Randomised Study Comparing the use of Propofol Versus Dexmedetomidine as a Sedative Agent for Patients Presenting for Lower Gastrointestinal Endoscopy

Volume: 15   Issue: 1
Pp: 61-66
Sameh A. Ahmed, Nehad Hawash, Fatma H. Rizk, Mahmoud Elkadeem, Mohamed Elbahnasawy and Sherief Abd-Elsalam*
DOI: 10.2174/1574885514666190904161705

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Volume: 15   Issue: 1
Pp: 1-1
Imran Ali
DOI: 10.2174/157488551501200114144207

Preface promotion: free to download

Volume: 15   Issue: 1
Pp: 2-2
Stefano Palomba
DOI: 10.2174/157488551501200114144349

Application of D-optimal Mixture Design for Development and Optimization of Olmesartan Medoxomil Loaded SMEDDS open access plus

Volume: 15   Issue:
Pp: 1-13
Navdeep Gahlawat, Ravinder Verma and Deepak Kaushik *
DOI: 10.2174/1574885515666200212094039

Synergy Effects of Metformin and Berberine on Glyoxal-Induced Carbonyl Stress in Isolated Rat Liver Mitochondria

Volume: 15   Issue:
Pp: 1-9
Mohsen Rezaei, Heibatullah Kalantari, Saeed Mehrzadi and Mehdi Goudarzi*
DOI: 10.2174/1574885515666200214122055

In-vitro Comparative Study of Different Brands of Metoclopramide Hydrochloride Tablets Marketed in Saudi Arabia

Volume: 15   Issue:
Pp: 1-6
Umme Hani*, Yahya Alhamhoom, Ali Alqahtani, Riyaz Ali Osmani, Mohammed Rahmatulla, Yasmeen Begum and Ekta Singh
DOI: 10.2174/1574885515666200305101840

Formulation Development and Characterization of Controlled Release Core-in-Cup Matrix Tablets of Venlafaxine HCl

Volume: 15   Issue:
Pp: 1-9
Balaji Maddiboyina, Vikas Jhawat*, Gandhi Sivaraman, Om Prakash Sunnapu, Ramya Krishna Nakkala, Mudavath Hanuma Naik and Monika Gulia
DOI: 10.2174/1574885515666200331104440

A Review on Experimental Methods for Diabetes Induction and Therapeutic Efficacy of Anti-Diabetic Drug Loaded Nanoformulation

Volume: 15   Issue:
Pp: 1-12
Mohamad Taleuzzaman*, Chandarkala Kala, Iqra Rahat, Sadaf Jamal Gilani, Vinay Kumar and Syed Sarim Imam
DOI: 10.2174/1574885515999200415114330

Systematic Development of Bicalutamide Immediate Release Pellets Using Aeroperl and Non-MCC Extruder Aid

Volume: 15   Issue:
Pp: 1-11
Hardik Rana*, Hussain Hasan, Mukesh Gohel, Vaishali Thakkar and Tejal Gandhi
DOI: 10.2174/1574885515999200424082315

A Concise Review on Multidimensional Silver Nanoparticle Health Aids and Threats

Volume: 15   Issue:
Pp: 1-16
Parmita Phaugat, Aparana Khansili*, Suchitra Nishal and Beena Kumari
DOI: 10.2174/1574885515999200425234517

Neuro-AIDS: Current Status and Challenges to Antiretroviral Drug Therapy (ART) for Its Treatment

Volume: 15   Issue:
Pp: 1-13
Smita P. Kakad* and Sanjay J. Kshirsagar
DOI: 10.2174/1574885515666200604123046

Central Composite Design for the Development and Evaluation of Floating-Mucoadhesive Tablets of Gliclazide

Volume: 15   Issue:
Pp: 1-11
Manoj Bansal, Ravinder Verma, Vineet Mittal and Deepak Kaushik*
DOI: 10.2174/1574885515999200623170251

Short Term Efficacy of Modified Epley’s Maneuvre Assisted by Visual Aid Dynamic Device Versus Unassisted Maneuvre for the Treatment of Posterior Canal BPPV

Volume: 15   Issue:
Pp: 1-5
Dhruvkumar M. Patel, Jayanti K. Gurumukhani, Mukundkumar V. Patel*, Maitri M. Patel, Chilvana Patel, Harsh D. Patel and Maurvi V. Patel
DOI: 10.2174/1574885515999200706013308

Assortment of Human Amniotic Membrane and Curcumin: a Potential Therapeutic Strategy for Burn Wound Healing

Volume: 15   Issue:
Pp: 1-8
Ayesha Siddika, Md. Arifuzzaman, Liakat Hossain, Md. Hasib Adnan, Farzana Diba, Md. Zahid Hasan, S.M. Asaduzzaman and Md Jamal Uddin*
DOI: 10.2174/1574885515999200706013824

CORONAVIRUS and COVID-19: A Systematic Review and Perspective

Volume: 15   Issue:
Pp: 1-13
Harshal Ashok Pawar*, Anjali Harshal Pawar, Sandip Ashok Pawar and Prashant Ashok Pawar
DOI: 10.2174/1574885515999200719142835

Development and Characterization of LBG-PVA Interpenetrating Networks Incorporating Gliclazide for Sustained Release

Volume: 15   Issue:
Pp: 1-11
Ashish Katoch, Manju Nagpal*, Malkiet Kaur, Manjinder Singh, Geeta Aggarwal and Gitika Arora Dhingra
DOI: 10.2174/1574885515999200719143513

Quality-by-Design Enabled Chitosan Nanoparticles for Antitubercular Therapy: Formulation, Statistical Optimization, and In vitro Characterization

Volume: 15   Issue:
Pp: 1-20
Manasi M. Chogale, Sujay S. Gaikwad, Savita P. Kulkarni and Vandana B. Patravale*
DOI: 10.2174/1574885515666200722150305

Role of Biorelevant Media in Estimation of in vitro Lipolysis and Food Impact on Self-emulsifying Drug Delivery Systems.

Volume: 15   Issue:
Pp: 1-13
Ravinder Verma and Deepak Kaushik*
DOI: 10.2174/1574885515999200727121540

Development & Pharmaceutical Characterization of Isoniazid Loaded Solid Lipid Nanoparticle Drug Delivery Approach

Volume: 14   Issue: 3
Pp: 228-238
Swatantra Kumar Singh Kushwaha*, Awani Kumar Rai and Heena Parveen
DOI: 10.2174/1574885514666190103114200

Formulation of Dry Powder Inhaler of Anti-tuberculous Drugs Using Spray Drying Technique and Optimization Using 23 Level Factorial Design Approach

Volume: 14   Issue: 3
Pp: 239-260
Vaishali Thakkar*, Ekta Pandey, Tosha Pandya, Purvi Shah, Asha Patel, Roma Trivedi, Mukesh Gohel, Lalji Baldaniya and Tejal Gandhi
DOI: 10.2174/1574885514666190104114209

Analysis of Safety Outcomes in Chronic Hepatitis C Patients using Interferon-free Treatment: A Systematic Review of Case Reports

Volume: 14   Issue: 3
Pp: 210-219
Vinicius Lins Ferreira*, Leticia Paula Leonart, Ana Maria Della Rocca and Roberto Pontarolo
DOI: 10.2174/1574885514666190130162547

Drug/Vehicle Impacts and Formulation Centered Stratagems for Enhanced Transdermal Drug Permeation, Controlled Release and Safety: Unparalleled Past and Recent Innovations-An Overview open access plus

Volume: 14   Issue: 3
Pp: 192-209
Balamurugan Manickam*, Rajesh Sreedharan and Kumarappan Chidambaram
DOI: 10.2174/1574885514666190212113754

Equibiotic-GI Consumption Improves Intestinal Microbiota in Subjects with Functional Dyspepsia

Volume: 14   Issue: 3
Pp: 220-227
Berenice Palacios-González*, Noemí Meraz-Cruz, Fernanda Valdez-Palomares and Rafael Nambo-Venegas
DOI: 10.2174/1574885514666190212114412

Ramelteon in the Treatment of Delirium: New Perspectives from Reported Findings and a Case Observation

Volume: 14   Issue: 3
Pp: 184-191
Deborah L. Sanchez, Adam J. Fusick, William B. Hudson, Jourdan E. Schmitz, Maria C. Catalano and Glenn Catalano*
DOI: 10.2174/1574885514666190308161421

A Study of Prescription Pattern and Compliance of Anti-hypertensives with the Treatment Guidelines in Aseer Region; Saudi Arabia open access plus

Volume: 14   Issue: 3
Pp: 261-266
Ayesha Siddiqua*, Afaf Alshehri, Amal M. Alahmari, Rawan A. Alshehri and Somayh S. Badawy
DOI: 10.2174/1574885514666190424155014

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Volume: 14   Issue: 3
Pp: 183-183
Yanmin Zhang
DOI: 10.2174/157488551403191023124455

ACKNOWLEDGEMENTS TO REVIEWERS promotion: free to download

Volume: 14   Issue: 3
Pp: 267-267

DOI: 10.2174/157488551403191023150841

Strategically Placed Trifluoromethyl Substituent in the Realm of Antitubercular Drug Design

Volume: 14   Issue: 2
Pp: 114-123
Sidhartha S. Kar and Cinu A. Thomas*
DOI: 10.2174/1574885513666180906101732

Role of Unani Medicines in Cancer Control and Management

Volume: 14   Issue: 2
Pp: 92-113
Imran Ali*, Mohd. Suhail, Mohd. Farooq Naqshbandi, Mohd. Fazil, Bilal Ahmad and Ahmad Sayeed
DOI: 10.2174/1574885513666180907103659

Comparison of Mono-dopaminergic and Multi-target Pharmacotherapies in Primary Parkinson Syndrome and Assessment Tools to Evaluate Motor and Non-motor Symptoms

Volume: 14   Issue: 2
Pp: 124-134
Felix-Martin Werner* and Rafael Coveñas
DOI: 10.2174/1574885513666181115104137

Drug in Adhesive Transdermal Formulation of Valsartan and Nifedipine: Pharmacokinetics and Pharmacodynamics in Rats

Volume: 14   Issue: 2
Pp: 153-167
Jatin Sood, Bharti Sapra and Ashok K. Tiwary*
DOI: 10.2174/1574885514666181120114635

Systematic Scrutinisation of Vital Factors for Fabrication and Evaluation of PGS-MCC Based Drug Loaded Pellets by Extrusion Spheronization Technique

Volume: 14   Issue: 2
Pp: 168-182
Hardik Rana, Vaishali Thakkar*, Kalpana Mudgal, Mukesh Gohel, Lalji Baldania, Mansi Dholakia and Tejal Gandhi
DOI: 10.2174/1574885514666181123152641

Local Drug Delivery Based Treatment Approaches for Effective Management of Periodontitis

Volume: 14   Issue: 2
Pp: 135-152
Geeta Aggarwal, Sonia Verma, Madhu Gupta and Manju Nagpal*
DOI: 10.2174/1574885514666190103112855

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Volume: 14   Issue: 2
Pp: 91-91
Monica Mita
DOI: 10.2174/157488551402190802113751

Comparison of Valvulopathy Risk with Lorcaserin and Phenterminetopiramate for Weight Loss

Volume: 14   Issue: 1
Pp: 74-78
Michael Guo, Mahyar Etminan* and Bruce Carleton
DOI: 10.2174/1574885513666180503141557

Molecular Docking Study for Analyzing the Inhibitory Effect of Anti-inflammatory Plant Compound Against Tumour Necrosis Factor (TNF-α)

Volume: 14   Issue: 1
Pp: 85-90
Sagarika Biswas*
DOI: 10.2174/1574885513666180503145352