Abstract
Objective: Neuraxial administration of steroids have been used in clinical practice for more than 50 years and have a well defined place in the treatment of radicular low back pain. However, steroids have widespread effects on almost all body systems, such as suppression of the pituitary-adrenal axis with consecutive weight gain and osteoporosis. Methods: We prospectively evaluated the effect of three consecutive epidural steroid injections with 40 mg. methylprednisolone acetate once monthly for 3 months on weight gain. The study population included 108 patients, who attended the pain clinic for chronic low back pain. Completed data were available for 100 patients. Results: We found no significant change in weight after administration of a series of three-epidural steroid injections. Discussion: It appears that neuraxial steroids administration doesnt induce weight gain.
Keywords: Epidural steroid injection, weight gain, low back pain
Current Drug Safety
Title: Epidural Steroid Injections Do Not Induce Weight Gain
Volume: 2 Issue: 2
Author(s): Silviu Brill, Andrei Swartz and Gherta Brill
Affiliation:
Keywords: Epidural steroid injection, weight gain, low back pain
Abstract: Objective: Neuraxial administration of steroids have been used in clinical practice for more than 50 years and have a well defined place in the treatment of radicular low back pain. However, steroids have widespread effects on almost all body systems, such as suppression of the pituitary-adrenal axis with consecutive weight gain and osteoporosis. Methods: We prospectively evaluated the effect of three consecutive epidural steroid injections with 40 mg. methylprednisolone acetate once monthly for 3 months on weight gain. The study population included 108 patients, who attended the pain clinic for chronic low back pain. Completed data were available for 100 patients. Results: We found no significant change in weight after administration of a series of three-epidural steroid injections. Discussion: It appears that neuraxial steroids administration doesnt induce weight gain.
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Cite this article as:
Brill Silviu, Swartz Andrei and Brill Gherta, Epidural Steroid Injections Do Not Induce Weight Gain, Current Drug Safety 2007; 2 (2) . https://dx.doi.org/10.2174/157488607780598322
DOI https://dx.doi.org/10.2174/157488607780598322 |
Print ISSN 1574-8863 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3911 |
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