Current Drug Targets


Francis J. Castellino
(14643 citations)
Dean Emeritus, College of Science,
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Most Accessed Articles

Amendatory Effect of Flavonoids in Alzheimer's Disease Against Mitochondrial Dysfunction

Volume: 22   Issue: 14
Pp: 1618-1628
Hayrettin Ozan Gulcan and Ilkay E. Orhan*
DOI: 10.2174/1389450122666210120144921

An Insight Into Mitochondrial Dysfunction and its Implications in Neurological Diseases

Volume: 22   Issue: 14
Pp: 1585-1595
Rashid Waseem, Anas Shamsi, Syed N. Kazim and Asimul Islam*
DOI: 10.2174/1389450121999201230204050

Cerebrovascular Complications of Diabetes: SGLT-2 Inhibitors as a Promising Future Therapeutics

Volume: 22   Issue: 14
Pp: 1629-1636
Vishal Chavda, Ruju Vashi and Snehal S. Patel*
DOI: 10.2174/1389450121666201020163454

Role of Mitochondrial Heat-shock Proteins and Immunophilins in Neuro Degenerative Diseases

Volume: 22   Issue: 14
Pp: 1596-1617
Cristina Daneri-Becerra, Sol M. Ciucci, Gisela Mazaira and Mario D. Galigniana*
DOI: 10.2174/1389450121999201230204320

Aging of Brain Related with Mitochondrial Dysfunctions

Volume: 22   Issue: 14
Pp: 1668-1687
Vipin Dhote*, Prem Samundre, Aditya Ganeshpurkar and Aman Upaganlawar
DOI: 10.2174/1389450121999201209202247

Impaired Quality Control of Mitochondria Underlying the Pathogenesis of Alzheimer's Disease

Volume: 22   Issue: 14
Pp: 1578-1584
Md. Sahab Uddin*, Umme Tabassum Arobi Katha and Ghulam Md Ashraf*
DOI: 10.2174/1389450122666210309105326

Current Perspectives of Healthy Mitochondrial Function for Healthy Neurons

Volume: 22   Issue: 14
Pp: 1688-1703
Arunachalam Muthuraman*, Muthusamy Ramesh*, Venkataratinakumar Thiagarajan, Sumeet K. Singla, Seema Mudhol and Serva P. Muthukumar
DOI: 10.2174/1389450122666210222163528

GSK-3 Inhibitors in the Regulation and Control of Colon Carcinoma

Volume: 22   Issue: 13
Pp: 1485-1495
Sitansu S. Nanda, Md Imran Hossain, Heongkyu Ju and Dong Kee Yi*
DOI: 10.2174/1389450122666210204203950

Glycogen Synthase Kinase-3 (GSK-3) Inhibitors as a New Lead for Treating Breast and Ovarian Cancer

Volume: 22   Issue: 13
Pp: 1548-1554
Phool Chandra*, Neetu Sachan and Dilipkumar Pal
DOI: 10.2174/1389450122666210203183351

Remdesivir and Hydroxychloroquine: A Compassionate Use in Covid-19

Volume: 22   Issue: 13
Pp: 1536-1547
Amritpal Kaur, Gaurav Chaudhary, Pargat Singh, Sandeep Arora and Rajwinder Kaur*
DOI: 10.2174/1389450121999201228212842

The Role of Non-coding Genome in Cancer-associated Fibroblasts; Stateof- the-Art and Perspectives in Cancer Targeted Therapy

Volume: 22   Issue: 13
Pp: 1524-1535
Arezoo G. Shabgah, Hamed Mohammadi, Pouya Goleij, Mahdiyeh Hedayati-Moghadam, Arash Salmaninejad and Jamshid G. Navashenaq*
DOI: 10.2174/1389450122666210216091953

Role of GSK-3 in Cardiac Health: Focusing on Cardiac Remodeling and Heart Failure

Volume: 22   Issue: 13
Pp: 1568-1576
Ubaid Tariq, Shravan K. Uppulapu and Sanjay K. Banerjee*
DOI: 10.2174/1389450122666210224105430

GSK-3 Inhibitors as New Leads to Treat Type-II Diabetes

Volume: 22   Issue: 13
Pp: 1555-1567
Gowru Srivani, Ramyakrishna Sharvirala, Prabhakar Reddy Veerareddy, Dilipkumar Pal and Gangarapu Kiran*
DOI: 10.2174/1389450122666210120144428

Review of the Biological Activity of Maslinic Acid

Volume: 22   Issue: 13
Pp: 1496-1506
Zhang Jing, Wang Rui, Li Ruihua, Yu Hao* and Fang Hengtong*
DOI: 10.2174/1389450122666210308111159

Recent Advancement in Topical Drug Delivery for Psoriasis: Clinical Pertinence and Potential Market

Volume: 22   Issue: 13
Pp: 1507-1523
Rakhi Kumari, Jitu Halder, Amit Sharma and Vineet Kumar Rai*
DOI: 10.2174/1389450122666210412124256

Remdesivir (GS-5734) in COVID-19 Therapy: The Fourth Chance

Volume: 22   Issue: 12
Pp: 1346-1356
Dinesh S. Moirangthem and Laishram Surbala*
DOI: 10.2174/1389450121999201202110303

Antibiotic Adjuvants: A Promising Approach to Combat Multidrug Resistant Bacteria

Volume: 22   Issue: 12
Pp: 1334-1345
Namita Sharma, Anil K. Chhillar*, Sweety Dahiya, Pooja Choudhary, Aruna Punia and Prity Gulia
DOI: 10.2174/1389450122666210120084406

Novel Strategies to Combat the Emerging Drug Resistance in Human Pathogenic Microbes

Volume: 22   Issue: 12
Pp: 1424-1436
Hafsa Qadri, Abdul H. Shah* and Manzoor Mir*
DOI: 10.2174/1389450121666201228123212