Current Drug Targets

Editor-in-Chief

Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556
(USA)

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Articles Ahead of Print

Aging of Brain Related with Mitochondrial Dysfunctions

Volume:22
Vipin Dhote*, Prem Samundre, Aditya Ganeshpurkar and Aman Upaganlawar

Recent Advances in Nanotechnology-Based Drug Delivery Approaches for Alzheimer disease

Volume:22
Ishnoor Kaur, Arun Kumar*, Tapan Behl and Dhruv Setia

Self-Assembled Micelles of Amphiphilic PEGylated Drugs for Cancer Treatment

Volume:22
Majdi Al-Amili, Zhu Jin, Zhongmin Wang* and Shengrong Guo*

A Review on Rheumatoid Arthritis Interventions and Current Develop-ments

Volume:22
Nikita Khanna, Anil Kumar and Sandip Pawar

Insight γ-Secretase: Structure, Function and Role in Alzheimer’s Disease

Volume:22
Suvadeep Mal, Udita Malik, Dilipkumar Pal* and Abhishek Mishra

An Insight Into Mitochondrial Dysfunction and its Implications in Neurological Diseases

Volume:22
Rashid Waseem, Anas Shamsi, Syed Kazim and Asimul Islam*

Artificial Intelligence, Big data and Machine Learning approaches in Precision Medicine & Drug Discovery

Volume:22
Anuraj Nayarisseri*, Ravina Khandelwal, Poonam Tanwar, Maddala Madhavi, Diksha Sharma, Garima Thakur, Alejandro Speck-Planche and Sanjeev Kumar Singh

Nanosponges Encapsulated Phytochemicals for Targeting Cancer: A Review

Volume:21
Shailaja Dombe* and Pramodkumar Shirote

Natural Products as Anticancer Agents

Volume:22
Ruby Varghese and Yogesh Bharat. Dalvi*

Role of Mitochondrial Heat-shock Proteins and Immunophilins in Neuro degenerative Diseases

Volume:22
Cristina Daneri-Becerra, Sol M. Ciucci, Gisela Mazaira and Mario D. Galigniana*

Remdesivir and Hydroxychloroquine: A Compassionate Use in Covid-19

Volume:21
Amritpal Kaur, Gaurav Chaudhary, Pargat Singh, Sandeep Arora and Rajwinder Kaur*

A Review on Screening Models for Potential Therapeutic Candidates and Targets Against SARS-CoV-2

Volume:21
Mohana Das, Manish Kumar, Abhishek Jha, Madhukiran D.R, Kanchan Bharti, Shomedeep Mondal and Brahmeshwar Mishra*

Target Genetic Abnormalities for the Treatment of Colon Cancer and Its Progression to Metastasis

Volume:21
Tushar Baviskar, Munira Momin, Jingwen Liu, Bin Guo and Lokesh Bhatt*

Colorectal Cancer Epidemiology: Recent Trends and Impact on Outcomes

Volume:21
Firas Baidoun, Kholoud Elshiwy, Yasmine Elkeraie, Zahi Merjaneh, George Khoudari, Muhammad Talal Sarmini, Mohamed Gad, Muneer Al-Husseini and Anas Saad*

Potential Role of In vitro-In vivo Correlations (IVIVC) for the Development of Plant-Derived Anticancer Drugs

Volume:21
A.Mohamed Sheik Tharik*, S.B. Santhosh, Murugesan Susitra Manjari and S.N. Meyyanathan

Remdesivir (GS-5734) in COVID-19 Therapy: The Fourth Chance

Volume:21
Dinesh Singh Moirangthem and Laishram Surbala *

New Paradigms to Help Decisions in Treatment Choice: Head to Head Trial of Biological Therapies in Inflammatory Bowel Diseases

Volume:21
Laura Loy*, Gionata Fiorino, Giulia Roda, Mariangela Allocca, Federica Furfaro, Alessandra Zilli, Daniela Gilardi, Simona Radice, Laurent Peyrin-Biroulet and Silvio Danese

Circulating Tumor DNA as a Biomarker for Outcomes Prediction in Colorectal Cancer Patients

Volume:21
Angelica Petrillo*, Massimiliano Salati, Dario Trapani and Michele Ghidini

Progress in Detection of Insomnia Sleep Disorder: A Comprehensive Review

Volume:21
Md Belal Bin Heyat, Faijan Akhtar, M.A. Ansari, Asif Khan, Fahed Alkahtani, Haroon Khan* and Dakun Lai*

Current Quest in Natural Bioactive Compounds for Alzheimer’s Disease: Multi-Targeted-Designed-Ligand Based Approach with Preclinical and Clinical Based Evidence

Volume:21
Ashif Iqubal, Syed Obaidur Rahman, Musheer Ahmed, Pratichi Bansal, Md Rafi Haider, Mohammad Kashif Iqubal, Abul Kalam Najmi, Faheem Hyder and Syed Ehtaishamul Haque*

Nanotechnology Based Approach for Hepatocellular Carcinoma Targeting

Volume:21
Abdulsalam Alhalmi, Sarwar Beg*, Kanchan Kohli, Md. Waris and Tanuja Singh

New Approaches for the Treatment of Chagas Disease

Volume:21
Ramendra Pati Pandey*, Marilda Savoia Nascimento, Catrin E Moore, V. Samuel Raj, Jorge Kalil and Edecio Cunha-Neto

In Silico Study Examining New Phenylpropanoids Targets with Antidepressant Activity

Volume:21
Poliane da Silva Calixto, Reinaldo Nóbrega de Almeida, Mirian G. S. Stiebbe Salvadori, Mayara dos Santos Maia, José Maria Barbosa Filho, Marcus Tullius Scotti and Luciana Scotti*

Management of Glioblastoma Multiforme by Phytochemicals: Applications of Nanoparticle-Based Targeted Drug Delivery System

Volume:21
Sayed Md Mumtaz, Gautam Bhardwaj, Shikha Goswami, Rajiv Kumar Tonk, Ramesh K. Goyal, Tareq Abu-Izneid and Faheem Hyder Pottoo*

Physcion and Physcion 8-O-β-D-glucopyranoside: Natural Anthraquinones with Potential Anticancer Activities

Volume:21
Muhammad Ajmal Shah*, Muhammad Adnan, Azhar Rasul*, Ghulam Hussain, Iqra Sarfraz, Bushra Nageen, Ammara Riaz, Rida Khalid, Muhammad Asrar, Zeliha Selamoglu, Şevki Adem and Satyajit D. Sarker

Inflammatory Bowel Disease in migrant populations – a narrative review

Volume:21
Maria Manuela Estevinho, Diogo José M. Lopes, Miguel Torre Souto and Fernando Magro*

Herbal Resources to Combat a Progressive & Degenerative Nervous System Disorder- Parkinson’s Disease

Volume:21
Bairong Shen*, Rajeev K. Singla, Tanya Agarwal and He Xuefei

Anti-platelet Drug-loaded Targeted Technologies for the Effective Treatment of Atherothrombosis

Volume:21
Selvakumar Muruganantham, Venkateshwaran Krishnaswami, Shanmugarathinam Alagarsamy and Ruckmani Kandasamy*

Post-menopausal Osteoporosis and Probiotics

Volume:21
Sangeeta Huidrom*, Mirza Atif Beg and Tariq Masood

An Agathokakological Tale of Δ9-THC: Exploration of Possible Biological Targets

Volume:21
Bijo Mathew*, Seetha Harilal, Arafa Musa, Rajesh Kumar, Della Grace Thomas Parambi, Jobin Jose, Md. Sahab Uddin, Muhammad Ajmal Shah, Tapan Behl and Mazhuvancherry Kesavan Unnikrishnan

Curcumin and its Multi-target Function Against Pain and Inflammation: An Update of Pre-clinical Data

Volume:21
Mohammad S. Mubarak*, Shaikh Jamal Uddin*, Md. Fahim Hasan, Mohasana Afroz, Dipto Kumar Sarker, Razina Rouf, Muhammad Torequl Islam and Jamil A. Shilpi

Antibiotic Potentiation of Natural Products: A Promising Target to Fight Pathogenic Bacteria

Volume:21
Mohamad Fawzi Mahomoodally* and Nabeelah Bibi Sadeer

MiRNA, a New Treatment Strategy for Pulmonary Fibrosis

Volume:21
Yanhong Liu, Hongguang Nie*, Yan Ding, Yapeng Hou, Kejun Mao and Yong Cui

Therapeutic Options for Treatment of COVID-19: A Review from Repur-posed Drugs to New Drug Targets

Volume:21
Bushra Akhtar, Faqir Muhammad*, Ali Sharif and Abdul Hannan

Alzheimer's Disease: Related Targets, Synthesis of Available Drugs, Bioactive Compounds Under Development and Promising Results Obtained from Multi-target Approaches

Volume:21
Natália F. F. Pirolla, Victor S. Batista, Flávia Pereira Dias Viegas, Vanessa Silva Gontijo, Caitlin R. McCarthy, Claudio Viegas Jr and Nailton M. Nascimento-Júnior*

To Explore the Potential Targets and Current Structure-based Design Strategies Utilizing Co-crystallized Ligand to Combat HCV

Volume:21
Heena Tarannum, Bhumika Chauhan, Asmita Samadder, Harekrishna Roy and Sisir Nandi*

A Critical Review of Second-Generation Anti-EGFR Monoclonal Antibodies in Metastatic Colorectal Cancer

Volume:21
Daniel Sur*, Andrei Havasi, Alecsandra Gorzo and Claudia Burz

Rediscovering Tocophersolan: A Renaissance for Nano-Based Drug Delivery and Nanotheranostic Applications

Volume:21
Dickson Pius Wande, Qin Cui, Shijie Chen, Cheng Xu, Hui Xiong and Jing Yao*

Withdrawal Notice: Preparation and Applications of Glyconanoparticles

Volume:19
Gangliang Huang*