Current Drug Targets


Francis J. Castellino
(14643 citations)
Dean Emeritus, College of Science,
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Volume: 9 Issue: 8, August

Editorial [Hot Topic: Peripheral Proteins as Drug Targets (Guest Editor: Robert V. Stahelin) ]

Volume:9   Issue: 8
Pp: 601-602
Robert V. Stahelin
DOI: 10.2174/138945008785132448
Published on: 01 March, 2012

Cellular Membranes and Lipid-Binding Domains as Attractive Targets for Drug Development

Volume:9   Issue: 8
Pp: 603-613
C. G. Sudhahar, R. M. Haney, Y. Xue and R. V. Stahelin
DOI: 10.2174/138945008785132420
Published on: 01 March, 2012

The Life and Death of Protein Kinase C

Volume:9   Issue: 8
Pp: 614-625
Christine M. Gould and Alexandra C. Newton
DOI: 10.2174/138945008785132411
Published on: 01 March, 2012

Diacylglycerol Kinases as Emerging Potential Drug Targets for a Variety of Diseases

Volume:9   Issue: 8
Pp: 626-640
Fumio Sakane, Shin-ichi Imai, Masahiro Kai, Satoshi Yasuda and Hideo Kanoh
DOI: 10.2174/138945008785132394
Published on: 01 March, 2012

Wealth of Opportunity - The C1 Domain as a Target for Drug Development

Volume:9   Issue: 8
Pp: 641-652
P. M. Blumberg, N. Kedei, N. E. Lewin, D. Yang, G. Czifra, Y. Pu, M. L. Peach and V .E. Marquez
DOI: 10.2174/138945008785132376
Published on: 01 March, 2012

Molecular Targeting of Acid Ceramidase: Implications to Cancer Therapy

Volume:9   Issue: 8
Pp: 653-661
Youssef H. Zeidan, Russell W. Jenkins, John B. Korman, Xiang Liu, Lina M. Obeid, James S. Norris and Yusuf A. Hannun
DOI: 10.2174/138945008785132358
Published on: 01 March, 2012

Targeting SphK1 as a New Strategy against Cancer

Volume:9   Issue: 8
Pp: 662-673
Dai Shida, Kazuaki Takabe, Dmitri Kapitonov, Sheldon Milstien and Sarah Spiegel
DOI: 10.2174/138945008785132402
Published on: 01 March, 2012

Ceramide Kinase and the Ceramide-1-Phosphate/cPLA2α Interaction as a Therapeutic Target

Volume:9   Issue: 8
Pp: 674-682
Nadia F. Lamour and Charles E. Chalfant
DOI: 10.2174/138945008785132349
Published on: 01 March, 2012

Group VI Phospholipases A2: Homeostatic Phospholipases with Significant Potential as Targets for Novel Therapeutics

Volume:9   Issue: 8
Pp: 683-697
W. P. Wilkins III and S. E. Barbour
DOI: 10.2174/138945008785132385
Published on: 01 March, 2012

Therapeutic Potential of Autotaxin/Lysophospholipase D Inhibitors

Volume:9   Issue: 8
Pp: 698-708
Lorenzo Federico, Zehra Pamuklar, Susan S. Smyth and Andrew J. Morris
DOI: 10.2174/138945008785132439
Published on: 01 March, 2012

ENaC and Its Regulatory Proteins as Drug Targets for Blood Pressure Control

Volume:9   Issue: 8
Pp: 709-716
Daniela Rotin and Laurent Schild
DOI: 10.2174/138945008785132367
Published on: 01 March, 2012