Current Drug Targets


Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Editorial [Hot Topic: Peripheral Proteins as Drug Targets (Guest Editor: Robert V. Stahelin) ] promotion: free to download

Volume:9   Issue: 8
Pp: 601-602
Robert V. Stahelin
DOI: 10.2174/138945008785132448

Cellular Membranes and Lipid-Binding Domains as Attractive Targets for Drug Development

Volume:9   Issue: 8
Pp: 603-613
C. G. Sudhahar, R. M. Haney, Y. Xue and R. V. Stahelin
DOI: 10.2174/138945008785132420

The Life and Death of Protein Kinase C

Volume:9   Issue: 8
Pp: 614-625
Christine M. Gould and Alexandra C. Newton
DOI: 10.2174/138945008785132411

Diacylglycerol Kinases as Emerging Potential Drug Targets for a Variety of Diseases

Volume:9   Issue: 8
Pp: 626-640
Fumio Sakane, Shin-ichi Imai, Masahiro Kai, Satoshi Yasuda and Hideo Kanoh
DOI: 10.2174/138945008785132394

Wealth of Opportunity - The C1 Domain as a Target for Drug Development

Volume:9   Issue: 8
Pp: 641-652
P. M. Blumberg, N. Kedei, N. E. Lewin, D. Yang, G. Czifra, Y. Pu, M. L. Peach and V .E. Marquez
DOI: 10.2174/138945008785132376

Molecular Targeting of Acid Ceramidase: Implications to Cancer Therapy

Volume:9   Issue: 8
Pp: 653-661
Youssef H. Zeidan, Russell W. Jenkins, John B. Korman, Xiang Liu, Lina M. Obeid, James S. Norris and Yusuf A. Hannun
DOI: 10.2174/138945008785132358

Targeting SphK1 as a New Strategy against Cancer

Volume:9   Issue: 8
Pp: 662-673
Dai Shida, Kazuaki Takabe, Dmitri Kapitonov, Sheldon Milstien and Sarah Spiegel
DOI: 10.2174/138945008785132402

Ceramide Kinase and the Ceramide-1-Phosphate/cPLA2α Interaction as a Therapeutic Target

Volume:9   Issue: 8
Pp: 674-682
Nadia F. Lamour and Charles E. Chalfant
DOI: 10.2174/138945008785132349

Therapeutic Potential of Autotaxin/Lysophospholipase D Inhibitors

Volume:9   Issue: 8
Pp: 698-708
Lorenzo Federico, Zehra Pamuklar, Susan S. Smyth and Andrew J. Morris
DOI: 10.2174/138945008785132439

ENaC and Its Regulatory Proteins as Drug Targets for Blood Pressure Control

Volume:9   Issue: 8
Pp: 709-716
Daniela Rotin and Laurent Schild
DOI: 10.2174/138945008785132367