Current Drug Targets


Francis J. Castellino
(14643 citations)
Dean Emeritus, College of Science,
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Volume: 9 Issue: 11, November

Editorial [Hot Topic:Current Antiparasitic Drug Targets and a Paradigm Shift in Discovery of New Antiparasitic Drugs and Vaccines(Guest Editor: Babu L. Tekwani)

Volume:9   Issue: 11
Pp: 921-921
Babu L. Tekwani
DOI: 10.2174/138945008786786145
Published on: 01 March, 2012

Discovering New Schistosome Drug Targets: The Role of Transcriptomics

Volume:9   Issue: 11
Pp: 922-930
Geoffrey N. Gobert and Malcolm K. Jones
DOI: 10.2174/138945008786786136
Published on: 01 March, 2012

Transcriptional Regulatory Networks in Entamoeba histolytica

Volume:9   Issue: 11
Pp: 931-937
Gretchen M. Ehrenkaufer and Upinder Singh
DOI: 10.2174/138945008786786109
Published on: 01 March, 2012

Discovery of Novel Vaccine Candidates and Drug Targets Against Visceral Leishmaniasis Using Proteomics and Transcriptomics

Volume:9   Issue: 11
Pp: 938-947
Shraddha Kumari, Awanish Kumar, Mukesh Samant, Neeloo Singh and Anuradha Dube
DOI: 10.2174/138945008786786091
Published on: 01 March, 2012

Targeting the Transcriptional and Translational Machinery of the Endosymbiotic Organelle in Apicomplexans

Volume:9   Issue: 11
Pp: 948-956
Tobias Fleige and Dominique Soldati-Favre
DOI: 10.2174/138945008786786073
Published on: 01 March, 2012

Glyoxalase Pathway of Trypanosomatid Parasites: A Promising Chemotherapeutic Target

Volume:9   Issue: 11
Pp: 957-965
Swati C. Chauhan, Prasad K. Padmanabhan and Rentala Madhubala
DOI: 10.2174/138945008786786082
Published on: 01 March, 2012

Characterizing the Bi-Subunit Type IB DNA Topoisomerase of Leishmania Parasites; a Novel Scenario for Drug Intervention in Trypanosomatids

Volume:9   Issue: 11
Pp: 966-978
Rosa M. Reguera, Rosario Diaz-Gonzalez, Yolanda Perez-Pertejo and Rafael Balana-Fouce
DOI: 10.2174/138945008786786118
Published on: 01 March, 2012

Trypanosome RNA Polymerases and Transcription Factors: Sensible Trypanocidal Drug Targets?

Volume:9   Issue: 11
Pp: 979-996
Luc Vanhamme
DOI: 10.2174/138945008786786064
Published on: 01 March, 2012

Plasmodium falciparum Serine/Threonine Phoshoprotein Phosphatases (PPP): From Housekeeper to the ‘Holy Grail’

Volume:9   Issue: 11
Pp: 997-1012
Joanna Bajsa, Stephen O. Duke and Babu L. Tekwani
DOI: 10.2174/138945008786786055
Published on: 01 March, 2012

Wnt Signaling in Liver Cancer

Volume:9   Issue: 11
Pp: 1013-1024
Yutaka Takigawa and Anthony M.C. Brown
DOI: 10.2174/138945008786786127
Published on: 01 March, 2012

Pigment Epithelium-Derived Factor (PEDF): Its Potential Therapeutic Implication in Diabetic Vascular Complications

Volume:9   Issue: 11
Pp: 1025-1029
Sho-ichi Yamagishi, Takanori Matsui, Kazuo Nakamura, So Ueda, Yoshihiro Noda and Tsutomu Imaizumi
DOI: 10.2174/138945008786786154
Published on: 01 March, 2012