Current Drug Targets


Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Editorial [ Hot Topic: Targets for Development of Drugs Against Orphan Diseases (Guest Editor: Walter Filgueira de Azevedo Jr.) ] promotion: free to download

Volume:8   Issue: 3
Pp: 387-387
Walter Filgueira de Azevedo
DOI: 10.2174/138945007780058960

Protein Kinases as Targets for Antiparasitic Chemotherapy Drugs

Volume:8   Issue: 3
Pp: 389-398
Fernanda Canduri, Patricia Cardoso Perez, Rafael A. Caceres and Walter F. de Azevedo
DOI: 10.2174/138945007780058979

Enoyl Reductases as Targets for the Development of Anti-Tubercular and Anti-Malarial Agents

Volume:8   Issue: 3
Pp: 399-411
J. S. Oliveira, I. B. Vasconcelos, I. S. Moreira, D. S. Santos and L. A. Basso
DOI: 10.2174/138945007780058942

Purine Nucleoside Phosphorylase: A Potential Target for the Development of Drugs to Treat T-Cell- and Apicomplexan Parasite-Mediated Diseases

Volume:8   Issue: 3
Pp: 413-422
R. G. Silva, J. E. S. Nunes, F. Canduri, J. C. Borges, L. M. Gava, F. B. Moreno, L. A. Basso and D. S. Santos
DOI: 10.2174/138945007780058997

Mycobacterial Shikimate Pathway Enzymes as Targets for Drug Design

Volume:8   Issue: 3
Pp: 423-435
R. G. Ducati, L. A. Basso and D. S. Santos
DOI: 10.2174/138945007780059004

Chorismate Synthase: An Attractive Target For Drug Development Against Orphan Diseases

Volume:8   Issue: 3
Pp: 437-444
Marcio V. B. Dias, Fernanda Ely, Mario S. Palma, Walter F. de Azevedo, Luiz A. Basso and Diogenes S. Santos
DOI: 10.2174/138945007780058924

The Inhibition of 5-enolpyruvylshikimate-3-phosphate Synthase as a Model for Development of Novel Antimicrobials

Volume:8   Issue: 3
Pp: 445-457
Mauricio Ribeiro Marques, Jose Henrique Pereira, Jaim S. Oliveira, Luiz Augusto Basso, Walter Filgueira de Azevedo, Diogenes Santiago Santos and Mario Sergio Palma
DOI: 10.2174/138945007780058951

Shikimate Kinase: A Potential Target for Development of Novel Antitubercular Agents

Volume:8   Issue: 3
Pp: 459-468
Jose H. Pereira, Igor B. Vasconcelos, Jaim S. Oliveira, Rafael A. Caceres, Walter F. de Azevedo, Luis A. Basso and Diogenes S. Santos
DOI: 10.2174/138945007780059013

Identifying and Attaining LDL-C Goals: Mission Accomplished? Next Target: New Therapeutic Options to Raise HDL-C Levels

Volume:8   Issue: 3
Pp: 483-488
Vasilios G. Athyros, Dimitri P. Mikhailidis, Anna I. Kakafika, Asterios Karagiannis, Apostolos Hatzitolios, Konstantinos Tziomalos, Emmanuel S. Ganotakis, Evangelos N. Liberopoulos and Moses Elisaf
DOI: 10.2174/138945007780058933

Erratum promotion: free to download

Volume:8   Issue: 3
Pp: 489-489

DOI: 10.2174/138945007780058915