Current Drug Targets

Editor-in-Chief

Francis J. Castellino
(14643 citations)
Dean Emeritus, College of Science,
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556
(USA)

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Volume: 8 Issue: 1, January

Author Index To Volume 7

Volume:8   Issue: 1
Pp: viii-viii
Bentham Science Publisher
DOI: 10.2174/138945011070801viii
Published on: 01 March, 2012

Subject Index To Volume 7

Volume:8   Issue: 1
Pp: xx-xxiii
Bentham Science Publisher
DOI: 10.2174/13894501107080100xx
Published on: 01 March, 2012

Editorial [Hot Topic: New Drugs and Drug Targets for Human Diseases Caused by Apicomplexan Parasites (Guest Editor: Frank Seeber)]

Volume:8   Issue: 1
Pp: 1-2
Frank Seeber
DOI: 10.2174/138945007779315588
Published on: 01 March, 2012

Isoprenoid Biosynthesis of the Apicoplast as Drug Target

Volume:8   Issue: 1
Pp: 3-13
Jochen Wiesner and Hassan Jomaa
DOI: 10.2174/138945007779315551
Published on: 01 March, 2012

Fatty Acid Biosynthesis as a Drug Target in Apicomplexan Parasites

Volume:8   Issue: 1
Pp: 15-30
C. D. Goodman and G. I. McFadden
DOI: 10.2174/138945007779315579
Published on: 01 March, 2012

Targeting Purine and Pyrimidine Metabolism in Human Apicomplexan Parasites

Volume:8   Issue: 1
Pp: 31-47
John E. Hyde
DOI: 10.2174/138945007779315524
Published on: 01 March, 2012

Mitochondrial Drug Targets in Apicomplexan Parasites

Volume:8   Issue: 1
Pp: 49-60
Michael W. Mather, Karl W. Henry and Akhil B. Vaidya
DOI: 10.2174/138945007779315632
Published on: 01 March, 2012

Targeting Invasion and Egress: From Tools to Drugs?

Volume:8   Issue: 1
Pp: 61-74
R. E. Morgan, K M. Evans, S. Patterson, F. Catti, G. E. Ward and N. J. Westwood
DOI: 10.2174/138945007779315678
Published on: 01 March, 2012

Targeting Nutrient Uptake Mechanisms in Plasmodium

Volume:8   Issue: 1
Pp: 75-88
Kiaran Kirk and Kevin J. Saliba
DOI: 10.2174/138945007779315560
Published on: 01 March, 2012

Editorial [Hot Topic: G-Protein-Coupled Receptors (GPCRs) and Drug Discovery (Guest Editor: Luca Gentilucci)]

Volume:8   Issue: 1
Pp: 89-90
Luca Gentilucci
DOI: 10.2174/138945007779315533
Published on: 01 March, 2012

Relaxin Receptors - New Drug Targets for Multiple Disease States

Volume:8   Issue: 1
Pp: 91-104
E. T. Van Der Westhuizen, R. J. Summers, M. L. Halls, R. A. D. Bathgate and P. M. Sexton
DOI: 10.2174/138945007779315650
Published on: 01 March, 2012

Corticotropin Releasing Hormone - A GPCR Drug Target

Volume:8   Issue: 1
Pp: 105-115
C. F. Hemley, A. McCluskey and P. A. Keller
DOI: 10.2174/138945007779315542
Published on: 01 March, 2012

Nociceptin/Orphanin FQ Peptide Receptors: Pharmacology and Clinical Implications

Volume:8   Issue: 1
Pp: 117-135
L.-C. Chiou, Y.-Y. Liao, P.-C. Fan, P.-H. Kuo, C.-H. Wang, C. Riemer and E. P. Prinssen
DOI: 10.2174/138945007779315605
Published on: 01 March, 2012

Agonist-Regulated Internalization and Desensitization of the Human Nociceptin Receptor Expressed in CHO Cells

Volume:8   Issue: 1
Pp: 137-146
S. Spampinato, M. Baiula and M. Calienni
DOI: 10.2174/138945007779315641
Published on: 01 March, 2012

Peptide Conversion - A Potential Pathway Modulating G-Protein Signaling

Volume:8   Issue: 1
Pp: 147-154
F. Nyberg and M. Hallberg
DOI: 10.2174/138945007779315597
Published on: 01 March, 2012

Effects of LPA and S1P on the Nervous System and Implications for Their Involvement in Disease

Volume:8   Issue: 1
Pp: 155-167
D. R. Herr and J. Chun
DOI: 10.2174/138945007779315669
Published on: 01 March, 2012

Structure, Pharmacology and Therapeutic Prospects of Family C G-Protein Coupled Receptors

Volume:8   Issue: 1
Pp: 169-184
Hans Brauner-Osborne, Petrine Wellendorph and Anders A. Jensen
DOI: 10.2174/138945007779315614
Published on: 01 March, 2012

Re-Discussion of the Importance of Ionic Interactions in Stabilizing Ligand-Opioid Receptor Complex and in Activating Signal Transduction

Volume:8   Issue: 1
Pp: 185-196
Luca Gentilucci, Federico Squassabia and Roberto Artali
DOI: 10.2174/138945007779315704
Published on: 01 March, 2012

Assessing Receptor Affinity for Inverse Agonists: Schild and Cheng-Prusoff Methods Revisited

Volume:8   Issue: 1
Pp: 197-202
Jesus Giraldo, Juan Serra, David Roche and Xavier Rovira
DOI: 10.2174/138945007779315687
Published on: 01 March, 2012