Current Drug Targets


Francis J. Castellino
(14643 citations)
Dean Emeritus, College of Science,
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Volume: 7 Issue: 7, July

Editorial [ The Reversal of Drug Resistance from Bacteria to Cancer Cells Part - I Guest Editor: Joseph Molnar ]

Volume:7   Issue: 7
Pp: 789-791
Joseph Molnar
DOI: 10.2174/138945006777709584
Published on: 01 March, 2012

Microbial Drug Efflux Proteins of the Major Facilitator Superfamily

Volume:7   Issue: 7
Pp: 793-811
Massoud Saidijam, Giulia Benedetti, Qinghu Ren, Zhiqiang Xu, Christopher J. Hoyle, Sarah L. Palmer, Alison Ward, Kim E. Bettaney, Gerda Szakonyi, Johan Meuller, Scott Morrison, Martin K. Pos, Patrick Butaye, Karl Walraven, Kate Langton, Richard B. Herbert, Ronald A. Skurray, Ian T. Paulsen, John O'Reilly, Nicholas G. Rutherford, Melissa H. Brown, Roslyn M. Bill and Peter J.F. Henderson
DOI: 10.2174/138945006777709575
Published on: 01 March, 2012

The Mechanism of Plasmid Curing in Bacteria

Volume:7   Issue: 7
Pp: 823-841
Gabriella Spengler, Annamaria Molnar, Zsuzsanna Schelz, Leonard Amaral, Derek Sharples and Joseph Molnar
DOI: 10.2174/138945006777709601
Published on: 01 March, 2012

Quinoline Derivatives as Promising Inhibitors of Antibiotic Efflux Pump in Multidrug Resistant Enterobacter Aerogenes Isolates

Volume:7   Issue: 7
Pp: 843-847
Abdallah Mahamoud, Jacqueline Chevalier, Anne Davin-Regli, Jacques Barbe and Jean-Marie Pages
DOI: 10.2174/138945006777709557
Published on: 01 March, 2012

Multi-Drug Resistance in Salmonella enterica: Efflux Mechanisms and Their Relationships with the Development of Chromosomal Resistance Gene Clusters

Volume:7   Issue: 7
Pp: 849-860
Teresa Quinn, Rebecca O'Mahony, Alan W. Baird, Denise Drudy, Paul Whyte and Seamus Fanning
DOI: 10.2174/138945006777709548
Published on: 01 March, 2012

Pharmacological Strategies for Overcoming Multidrug Resistance

Volume:7   Issue: 7
Pp: 861-879
S. Nobili, I. Landini, B. Giglioni and E. Mini
DOI: 10.2174/138945006777709593
Published on: 01 March, 2012

"Non-Antibiotics": Alternative Therapy for the Management of MDRTB and MRSA in Economically Disadvantaged Countries

Volume:7   Issue: 7
Pp: 887-891
Leonard Amaral, Miguel Viveiros and Jette E. Kristiansen
DOI: 10.2174/138945006777709539
Published on: 01 March, 2012

The Functions and Structure of ABC Transporters: Implications for the Design of New Inhibitors of Pgp and MRP1 to Control Multidrug Resistance (MDR)

Volume:7   Issue: 7
Pp: 893-909
E. Teodori, S. Dei, C. Martelli, S. Scapecchi and F. Gualtieri
DOI: 10.2174/138945006777709520
Published on: 01 March, 2012