Current Drug Targets


Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Editorial [Hot Topic: GSK-3 in Health and Disease (Guest Editor: H. Eldar-Finkelman)] promotion: free to download

Volume:7   Issue: 11
Pp: 1375-1375
Hagit Eldar-Finkelman
DOI: 10.2174/1389450110607011375

Glycogen Synthase Kinase-3 - An Overview of An Over-Achieving Protein Kinase

Volume:7   Issue: 11
Pp: 1377-1388
Lisa Kockeritz, Bradley Doble, Satish Patel and James R. Woodgett
DOI: 10.2174/1389450110607011377

Multiple Roles for Glycogen Synthase Kinase-3 as a Drug Target in Alzheimers Disease

Volume:7   Issue: 11
Pp: 1389-1397
Hui-Chuan Huang and Peter S. Klein
DOI: 10.2174/1389450110607011389

Targeting Glycogen Synthase Kinase-3 in the CNS: Implications for the Development of New Treatments for Mood Disorders

Volume:7   Issue: 11
Pp: 1399-1409
Todd D. Gould, Alyssa M. Picchini, Haim Einat and Husseini K. Manji
DOI: 10.2174/1389450110607011399

GSK3 at the Edge: Regulation of Developmental Specification and Cell Polarization open access plus

Volume:7   Issue: 11
Pp: 1411-1419
Leung Kim and Alan R. Kimmel
DOI: 10.2174/1389450110607011411

Glycogen Synthase Kinase-3 (GSK3) in Psychiatric Diseases and Therapeutic Interventions

Volume:7   Issue: 11
Pp: 1421-1434
Richard S. Jope and Myoung-Sun Roh
DOI: 10.2174/1389450110607011421

Role of Glycogen Synthase Kinase-3 in Insulin Resistance and Type 2 Diabetes

Volume:7   Issue: 11
Pp: 1435-1441
Erik J. Henriksen and Betsy B. Dokken
DOI: 10.2174/1389450110607011435

The Saccharomyces cerevisiae GSK-3β Homologs

Volume:7   Issue: 11
Pp: 1455-1465
Yona Kassir, Ifat Rubin-Bejerano and Yael Mandel- Gutfreund
DOI: 10.2174/1389450110607011455

Editorial [Hot Topic: Ageing (Guest Editors: H.-P. Deigner and R. Kinscherf)] promotion: free to download

Volume:7   Issue: 11
Pp: 1467-1468
Hans-Peter Deigner and Ralf Kinscherf
DOI: 10.2174/1389450110607011467

Foreseeable Pharmaceutical Repair of Age-Related Extracellular Damage

Volume:7   Issue: 11
Pp: 1469-1477
Aubrey D. N.J. de Grey
DOI: 10.2174/1389450110607011469

The Pharmacology of Ageing in Drosophila

Volume:7   Issue: 11
Pp: 1479-1483
Mahtab Jafari, Anthony D. Long, Laurence D. Mueller and Michael R. Rose
DOI: 10.2174/1389450110607011479

The Deficit in Low Molecular Weight Thiols as a Target for Antiageing Therapy

Volume:7   Issue: 11
Pp: 1505-1512
Wulf Droge, Ralf Kinscherf, Wulf Hildebrandt and Thomas Schmitt
DOI: 10.2174/1389450110607011505

Therapeutic Efficacy of Selegiline in Neurodegenerative Disorders and Neurological Diseases

Volume:7   Issue: 11
Pp: 1513-1529
Manuchair Ebadi, Holly Brown-Borg, Jun Ren, Sushil Sharma, Shaik Shavali, Hesham El ReFaey and Edward C. Carlson
DOI: 10.2174/1389450110607011513

The Endocannabinoid System in Ageing: A New Target for Drug Development

Volume:7   Issue: 11
Pp: 1539-1552
A. Paradisi, S. Oddi and Maccarrone
DOI: 10.2174/1389450110607011539