Current Drug Targets


Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Preface: Highlights of Recent Progress in Alzheimers Disease Research [ Hot Topics in Alzheimers Disease Research (Guest Editor: Debomoy K. Lahiri)] promotion: free to download

Volume:5   Issue: 6
Pp: ii-ii
Debomoy K. Lahiri
DOI: 10.2174/13894501104050600ii

Posttranslational Modifications of Tau - Role in Human Tauopathies and Modeling in Transgenic Animals

Volume:5   Issue: 6
Pp: 503-515
Feng Chen, Della David, Alessandra Ferrari and Jurgen Gotz
DOI: 10.2174/1389450043345236

Cholesterol and Alzheimers Disease: Clinical and Experimental Models Suggest Interactions of Different Genetic, Dietary and Environmental Risk Factors

Volume:5   Issue: 6
Pp: 517-528
Kumar Sambamurti, Ann-Charlotte Granholm, Mark S. Kindy, Narayan R. Bhat, Nigel H. Greig, Debomoy K. Lahiri and Jacobo E. Mintzer
DOI: 10.2174/1389450043345335

Cytokines in Neuroinflammation and Alzheimers Disease

Volume:5   Issue: 6
Pp: 529-534
Mathias Cacquevel, Nathalie Lebeurrier, Simon Cheenne and Denis Vivien
DOI: 10.2174/1389450043345308

Metal and Inflammatory Targets for Alzheimers Disease

Volume:5   Issue: 6
Pp: 535-551
Jack T. Rogers and Debomoy K. Lahiri
DOI: 10.2174/1389450043345272

β-Sheet Breakers for Alzheimers Disease Therapy

Volume:5   Issue: 6
Pp: 553-558
Bieler S. and Soto C.
DOI: 10.2174/1389450043345290

Mitotic and Gender Parallels in Alzheimer Disease: Therapeutic Opportunities

Volume:5   Issue: 6
Pp: 559-563
X. Zhu, K. M. Webber, G. Casadesus, A. K. Raina, H. G. Lee, M. Marlatt, A. Hartzler, C. S. Atwood, R. Bowen, G. Perry and M. A. Smith
DOI: 10.2174/1389450043345317

A New Alzheimers Disease Interventive Strategy: GLP-1

Volume:5   Issue: 6
Pp: 565-571
Tracy Ann Perry and Nigel H. Greig
DOI: 10.2174/1389450043345245

The Role of Cytochrome P450 Enzymes in the Metabolism of Risperidone and Its Clinical Relevance for Drug Interactions

Volume:5   Issue: 6
Pp: 573-579
R. Berecz, P. Dorado, A. De La Rubia, M. C. Caceres, I. Degrell and A. LLerena
DOI: 10.2174/1389450043345263

Molecular Targets for Modulating Lung Inflammation and Injury

Volume:5   Issue: 6
Pp: 581-588
R. T. Sadikot, J. W. Christman and T. S. Blackwell
DOI: 10.2174/1389450043345281