Current Drug Targets


Francis J. Castellino
(14643 citations)
Dean Emeritus, College of Science,
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Volume: 22 Issue: 9, July 2021

Meet Our Editorial Board Member free to download

Volume:22   Issue: 9
Pp: 967-967
Chen Chen
DOI: 10.2174/138945012209210609093047

Microsatellite Instability as a Predictor of Outcomes in Colorectal Cancer in the Era of Immune-Checkpoint Inhibitors

Volume:22   Issue: 9
Pp: 968-976
Csongor György Lengyel*
DOI: 10.2174/1389450122666210325121322
Published on: 24 March, 2021

Preclinical Drug Discovery in Colorectal Cancer: A Focus on Natural Compounds

Volume:22   Issue: 9
Pp: 977-997
Heshu Sulaiman Rahman*
DOI: 10.2174/1389450122666210405105206
Published on: 04 April, 2021

Colorectal Cancer Epidemiology: Recent Trends and Impact on Outcomes

Volume:22   Issue: 9
Pp: 998-1009
Firas Baidoun, Kholoud Elshiwy, Yasmine Elkeraie, Zahi Merjaneh, George Khoudari, Muhammad Talal Sarmini, Mohamed Gad, Muneer Al-Husseini and Anas Saad*
DOI: 10.2174/1389450121999201117115717
Published on: 16 November, 2020

Circulating Tumor DNA as a Biomarker for Outcomes Prediction in Colorectal Cancer Patients

Volume:22   Issue: 9
Pp: 1010-1020
Angelica Petrillo*, Massimiliano Salati, Dario Trapani and Michele Ghidini
DOI: 10.2174/1389450121999201103194248
Published on: 03 November, 2020

The Emergence of Immune-checkpoint Inhibitors in Colorectal Cancer Therapy

Volume:22   Issue: 9
Pp: 1021-1033
Michele Ghidini*, Nicola Fusco, Massimiliano Salati, Shelize Khakoo, Gianluca Tomasello, Fausto Petrelli, Dario Trapani and Angelica Petrillo
DOI: 10.2174/1389450122666210204204415
Published on: 04 February, 2021

A Critical Review of Second-Generation Anti-EGFR Monoclonal Antibodies in Metastatic Colorectal Cancer

Volume:22   Issue: 9
Pp: 1034-1042
Daniel Sur*, Andrei Havasi, Alecsandra Gorzo and Claudia Burz
DOI: 10.2174/1389450121666200727121011
Published on: 27 July, 2020

Advances in Early Detection of Colorectal Cancer: A Focus on Non-invasive Biomarkers

Volume:22   Issue: 9
Pp: 1043-1053
Nadia El Kadmiri*
DOI: 10.2174/1389450122666210303100048
Published on: 02 March, 2021

Anti-VEGF Therapy in Myopic CNV

Volume:22   Issue: 9
Pp: 1054-1063
Lisa Toto*, Luca Di Antonio, Olivia Costantino and Rodolfo Mastropasqua
DOI: 10.2174/1389450122999210128180725
Published on: 28 January, 2021

The Regulatory Role of Rho GTPases and their Substrates in Osteoclastogenesis

Volume:22   Issue: 9
Pp: 1064-1070
Lin Gao, Lingbo Kong and Yuanting Zhao*
DOI: 10.2174/1389450121666200925150446
Published on: 25 September, 2020

Elucidation of Abnormal Extracellular Regulated Kinase (ERK) Signaling and Associations with Syndromic and Non-syndromic Autism

Volume:22   Issue: 9
Pp: 1071-1086
Aarti Tiwari, Saloni Rahi and Sidharth Mehan*
DOI: 10.2174/1389450121666201020155010
Published on: 20 October, 2020

Corrigendum to: Can Medical Therapy Fix Sexual Dysfunction after Major Pelvic and Prostate Surgery and does it Work for Kidney Stones? Chemotherapy before Cystectomy, New Schemes for which Patients? free to download

Volume:22   Issue: 9
Pp: 1087-1087
Petros Sountoulides, Ioannis Mykoniatis, Ioannis Vakalopoulos and Luca Cindolo*
DOI: 10.2174/138945012209210609101710