Current Drug Targets


Francis J. Castellino
(14643 citations)
Dean Emeritus, College of Science,
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

Personal Subscription
Become EABM
Become Reviewer
Call for Editor
Volume: 20 Issue: 9, July 2019

Targeting DNA Double-Strand Break (DSB) Repair to Counteract Tumor Radio-resistance

Volume:20   Issue: 9
Pp: 891-902
Yucui Zhao and Siyu Chen*
DOI: 10.2174/1389450120666190222181857
Published on: 22 February, 2019

Age-related Macular Degeneration: Current Knowledge of Zinc Metalloproteinases Involvement

Volume:20   Issue: 9
Pp: 903-918
Francesca Liva, Doretta Cuffaro, Elisa Nuti, Susanna Nencetti, Elisabetta Orlandini, Giovanni Vozzi and Armando Rossello*
DOI: 10.2174/1389450120666190122114857
Published on: 21 January, 2019

Potential Therapeutic Applications of P2 Receptor Antagonists: From Bench to Clinical Trials

Volume:20   Issue: 9
Pp: 919-937
Natiele C. da Silva Ferreira, Luiz A. Alves and Rômulo J. Soares-Bezerra*
DOI: 10.2174/1389450120666190213095923
Published on: 12 February, 2019

Trans-sialidase Associated with Atherosclerosis: Defining the Identity of a Key Enzyme Involved in the Pathology

Volume:20   Issue: 9
Pp: 938-941
Victor Y. Glanz, Veronika A. Myasoedova, Andrey V. Grechko and Alexander N. Orekhov*
DOI: 10.2174/1389450120666190308111619
Published on: 07 March, 2019

Saccharomyces cerevisiae (Baker’s Yeast) as an Interfering RNA Expression and Delivery System open access plus

Volume:20   Issue: 9
Pp: 942-952
Molly Duman-Scheel*
DOI: 10.2174/1389450120666181126123538
Published on: 26 November, 2018

The Plasminogen Activation System Promotes Neurorepair in the Ischemic Brain open access plus

Volume:20   Issue: 9
Pp: 953-959
Manuel Yepes*
DOI: 10.2174/1389450120666181211144550
Published on: 11 December, 2018

Developing Practical Therapeutic Strategies that Target Protein SUMOylation open access plus

Volume:20   Issue: 9
Pp: 960-969
Olivia F. Cox and Paul W. Huber*
DOI: 10.2174/1389450119666181026151802
Published on: 26 October, 2018

The Urokinase Plasminogen Activation System in Rheumatoid Arthritis: Pathophysiological Roles and Prospective Therapeutic Targets open access plus

Volume:20   Issue: 9
Pp: 970-981
Benjamin J. Buckley*, Umar Ali, Michael J. Kelso and Marie Ranson
DOI: 10.2174/1389450120666181204164140
Published on: 04 December, 2018

Current Understanding of Group A Streptococcal Biofilms open access plus

Volume:20   Issue: 9
Pp: 982-993
Heema K.N. Vyas, Emma-Jayne Proctor, Jason McArthur, Jody Gorman and Martina Sanderson-Smith*
DOI: 10.2174/1389450120666190405095712
Published on: 04 April, 2019