Current Drug Targets


Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Cellular Senescence and Anti-Cancer Therapy

Volume:20   Issue: 7
Pp: 705-715
Jieqiong You, Rong Dong, Meidan Ying, Qiaojun He, Ji Cao * and Bo Yang*
DOI: 10.2174/1389450120666181217100833
Published on: 09 May, 2019

Cyclin-Dependent Kinase 2 in Cellular Senescence and Cancer. A Structural and Functional Review

Volume:20   Issue: 7
Pp: 716-726
Priscylla Andrade Volkart, Gabriela Bitencourt-Ferreira, André Arigony Souto* and Walter Filgueira de Azevedo *
DOI: 10.2174/1389450120666181204165344
Published on: 09 May, 2019

Heat Shock Proteins (HSPs): A Novel Target for Cancer Metastasis Prevention

Volume:20   Issue: 7
Pp: 727-737
Vinayak Narayanankutty , Arunaksharan Narayanankutty* and Anusree Nair
DOI: 10.2174/1389450120666181211111815
Published on: 09 May, 2019

The Impact of Statin Therapy on the Survival of Patients with Gastrointestinal Cancer

Volume:20   Issue: 7
Pp: 738-747
Meysam Gachpazan, Hoda Kashani, Majid Khazaei, Seyed Mahdi Hassanian, Majid Rezayi, Fereshteh Asgharzadeh, Majid Ghayour-Mobarhan, Gordon A. Ferns and Amir Avan*
DOI: 10.2174/1389450120666181211165449
Published on: 09 May, 2019

Targeting Water in the Brain: Role of Aquaporin-4 in Ischemic Brain Edema

Volume:20   Issue: 7
Pp: 748-755
Muyassar Mamtilahun, Guanghui Tang, Zhijun Zhang, Yongting Wang, Yaohui Tang* and Guo-Yuan Yang*
DOI: 10.2174/1389450120666190214115309
Published on: 09 May, 2019

Recent Review on Subclass B1 Metallo-β-lactamases Inhibitors: Sword for Antimicrobial Resistance

Volume:20   Issue: 7
Pp: 756-762
Aditi Kaushik*, Manish Kaushik, Viney Lather and J.S. Dua
DOI: 10.2174/1389450120666181217101812
Published on: 09 May, 2019

Potential Applications of Induced Pluripotent Stem Cells for Cardiovascular Diseases

Volume:20   Issue: 7
Pp: 763-774
Xiaotong Wang, Zhenbo Han, Ying Yu, Zihang Xu, Benzhi Cai and Ye Yuan*
DOI: 10.2174/1389450120666181211164147
Published on: 09 May, 2019

Insight into Pain Modulation: Nociceptors Sensitization and Therapeutic Targets

Volume:20   Issue: 7
Pp: 775-788
Amna Khan, Salman Khan* and Yeong Shik Kim
DOI: 10.2174/1389450120666190131114244
Published on: 09 May, 2019

A Review of Preclinical Experiments Toward Targeting M2 Macrophages in Prostate Cancer

Volume:20   Issue: 7
Pp: 789-798
Farhad Seif, Laleh Sharifi, Majid Khoshmirsafa, Yasaman Mojibi and Monireh Mohsenzadegan *
DOI: 10.2174/1389450120666190123141553
Published on: 09 May, 2019