Current Drug Targets


Francis J. Castellino
(14643 citations)
Dean Emeritus, College of Science,
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Volume: 19 Issue: 5, April 2018

Meet Our Editorial Board Member free to download

Volume:19   Issue: 5
Pp: 407-407
Eva L. Feldman
DOI: 10.2174/138945011905180319095235
Published on: 18 March, 2018

Editorial: Bone Drug Targets free to download

Volume:19   Issue: 5
Pp: 408-408
Crispin R. Dass
DOI: 10.2174/138945011905180319095631
Published on: 18 March, 2018

Zoledronic Acid: Pleiotropic Anti-Tumor Mechanism and Therapeutic Outlook for Osteosarcoma

Volume:19   Issue: 5
Pp: 409-421
Zhengxiao Ouyang, Haowei Li, Zanjing Zhai, Jiake Xu, Crispin R. Dass, An Qin* and Kerong Dai*
DOI: 10.2174/1573399811666150615145409
Published on: 15 June, 2015

MicroRNAs as Potential Targets for Treatment of Osteoclast-Related Diseases

Volume:19   Issue: 5
Pp: 422-431
Haowei Li, Zanjing Zhai, Xinhua Qu, Jiake Xu, An Qin* and Kerong Dai*
DOI: 10.2174/1389450117666160502144329
Published on: 02 May, 2016

Doxorubicin Action on Mitochondria: Relevance to Osteosarcoma Therapy?

Volume:19   Issue: 5
Pp: 432-438
Jo Armstrong and Crispin R. Dass*
DOI: 10.2174/1389450116666150416115852
Published on: 15 April, 2015

Vitamin C and Bone Health: Evidence from Cell, Animal and Human Studies

Volume:19   Issue: 5
Pp: 439-450
Kok-Yong Chin and Soelaiman Ima-Nirwana*
DOI: 10.2174/1389450116666150907100838
Published on: 06 September, 2015

Urinary Bone Turnover Markers as Target Indicators for Monitoring Bisphosphonate Drug Treatment in the Management of Osteoporosis

Volume:19   Issue: 5
Pp: 451-459
Sohyea Kwon, Anne H. Wang, Cheryl A. Sadowski, Nese Yuksel and Michael R. Doschak*
DOI: 10.2174/1389450118666170704143529
Published on: 04 July, 2017

Systemic Delivery of Free Chitosan Accelerates Femur Fracture Healing in Rats

Volume:19   Issue: 5
Pp: 460-466
Peng Shao, Yongzhong Wei*, Crispin R. Dass, Guoying Zhang and Zhisheng Wu
DOI: 10.2174/1389450115666141010150255
Published on: 10 October, 2014

Alginate Bead-Encapsulated PEDF Induces Ectopic Bone Formation In Vivo in the Absence of Co-Administered Mesenchymal Stem Cells

Volume:19   Issue: 5
Pp: 467-478
Mina Elahy, Michael R. Doschak, Jeffery D. Hughes, Swati Baindur-Hudson and Crispin R. Dass*
DOI: 10.2174/1389450116666151001112455
Published on: 30 September, 2015

The Effect of Krill Oil and n-3 Polyunsaturated Fatty Acids on Human Osteosarcoma Cell Proliferation and Migration

Volume:19   Issue: 5
Pp: 479-486
Xiao Su, Philline Tanalgo, Marcel Bustos and Crispin R. Dass*
DOI: 10.2174/1389450116666150107152206
Published on: 07 January, 2015

JAK/STAT Signal Transduction: Promising Attractive Targets for Immune, Inflammatory and Hematopoietic Diseases

Volume:19   Issue: 5
Pp: 487-500
Qianwen Gao, Xuewu Liang, Abdul Sami Shaikh, Jie Zang, Wenfang Xu* and Yingjie Zhang*
DOI: 10.2174/1389450117666161207163054
Published on: 07 December, 2016

Targeting Cysteine Proteases from Plasmodium falciparum: A General Overview, Rational Drug Design and Computational Approaches for Drug Discovery

Volume:19   Issue: 5
Pp: 501-526
Boris D. Bekono, Fidele Ntie-Kang*, Luc C. Owono Owono* and Eugene Megnassan
DOI: 10.2174/1389450117666161221122432
Published on: 21 December, 2016

Recent Advances in Polymer-based Wound Dressings for the Treatment of Diabetic Foot Ulcer: An Overview of State-of-the-art

Volume:19   Issue: 5
Pp: 527-550
Zahid Hussain*, Hnin Ei Thu, Ahmad Nazrun Shuid, Haliza Katas and Fahad Hussain
DOI: 10.2174/1389450118666170704132523
Published on: 04 July, 2017

Recent Advances in Protein Tyrosine Phosphatase 1B Targeted Drug Discovery for Type II Diabetes and Obesity

Volume:19   Issue: 5
Pp: 551-575
Neelesh Maheshwari, Chandrabose Karthikeyan, Piyush Trivedi and N.S. Hari Narayana Moorthy*
DOI: 10.2174/1389450118666170222143739
Published on: 22 February, 2017