Current Drug Targets


Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Genetic Molecular Subtypes in Optimizing Personalized Therapy for Metastatic Colorectal Cancer

Volume:19   Issue: 15
Pp: 1731-1737
Marcin Włodarczyk*, Jakub Włodarczyk, Paweł Siwiński, Aleksandra Sobolewska-Włodarczyk and Jakub Fichna
DOI: 10.2174/1389450119666180803122744
Published on: 25 October, 2018

Current Strategies and Drug Targets in the Management of Type 2 Diabetes Mellitus

Volume:19   Issue: 15
Pp: 1738-1766
Paranjeet Kaur, Amit Mittal, Surendra Kumar Nayak, Manish Vyas, Vijay Mishra and Gopal L. Khatik*
DOI: 10.2174/1389450119666180727142902
Published on: 25 October, 2018

Nucleophagy Plays a Major Role in Human Diseases

Volume:19   Issue: 15
Pp: 1767-1773
Nian Fu, XueFeng Yang and Linxi Chen*
DOI: 10.2174/1389450119666180518112350
Published on: 25 October, 2018

Efficacy and Safety of Serotonin Receptor Ligands in the Treatment of Irritable Bowel Syndrome: A Review

Volume:19   Issue: 15
Pp: 1774-1781
Agata Binienda, Martin Storr, Jakub Fichna and Maciej Salaga*
DOI: 10.2174/1389450119666171227225408
Published on: 25 October, 2018

Recent Updates on Novel Approaches in Insulin Drug Delivery: A Review of Challenges and Pharmaceutical Implications

Volume:19   Issue: 15
Pp: 1782-1800
Manisha Pandey*, Hira Choudhury, Cheah Xiao Yi, Chen Wei Mun, Goh Khang Phing, Guee Xin Rou, Bhalqish Jeet Kaur A/P Ambar Jeet Singh, Angel Ng Ann Jhee, Lee Kai Chin, Prashant Kesharwani, Bapi Gorain and Zahid Hussain
DOI: 10.2174/1389450119666180523092100
Published on: 25 October, 2018

p53 as the Focus of Gene Therapy: Past, Present and Future

Volume:19   Issue: 15
Pp: 1801-1817
Joana F.A. Valente, João A. Queiroz and Fani Sousa*
DOI: 10.2174/1389450119666180115165447
Published on: 25 October, 2018

PPARγ-targeting Potential for Radioprotection

Volume:19   Issue: 15
Pp: 1818-1830
Simran Kaur, Alo Nag, Ajay Kumar Singh and Kulbhushan Sharma*
DOI: 10.2174/1389450119666180131105158
Published on: 25 October, 2018

S-Nitrosylation in Regulation of Inflammation and Cell Damage

Volume:19   Issue: 15
Pp: 1831-1838
Subhajit Dasgupta*, Jenny- Jaramillo Gomez, Inderjit Singh and Mushfiquddin Khan
DOI: 10.2174/1389450119666180213094747
Published on: 25 October, 2018

Nanotechnology Inspired Advanced Engineering Fundamentals for Optimizing Drug Delivery

Volume:19   Issue: 15
Pp: 1839-1854
Ahmed Alaa Kassem*
DOI: 10.2174/1389450119666180207092831
Published on: 25 October, 2018

Molecular Interactions of Different Steroids Contributing to Sebum Production. Review

Volume:19   Issue: 15
Pp: 1855-1865
Marisa Cabeza*, Lucero Bautista, Marisol G. Bravo and Yvonne Heuze
DOI: 10.2174/1389450119666180808113951
Published on: 25 October, 2018

Synthesis and Activity of Epothilone D

Volume:19   Issue: 15
Pp: 1866-1870
Hao Cheng and Gangliang Huang*
DOI: 10.2174/1389450119666180803122118
Published on: 25 October, 2018