Current Drug Targets


Francis J. Castellino
(14643 citations)
Dean Emeritus, College of Science,
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Volume: 18 Issue: 4, March 2017

Meet Our Editorial Board Member free to download

Volume:18   Issue: 4
Pp: 375-375
Mark J. Walker
DOI: 10.2174/138945011804170206191156
Published on: 06 February, 2017

Editorial (Thematic Issue: CML HSCs: Are the True Enemies for the Patient?) free to download

Volume:18   Issue: 4
Pp: 376-376
Manuela Mancini
DOI: 10.2174/138945011804170206191356
Published on: 06 February, 2017

Cellular and Molecular Networks in Chronic Myeloid Leukemia: The Leukemic Stem, Progenitor and Stromal Cell Interplay

Volume:18   Issue: 4
Pp: 377-388
Danilo Perrotti, Giovannino Silvestri, Lorenzo Stramucci, Justine Yu and Rossana Trotta
DOI: 10.2174/1389450117666160615074120
Published on: 14 June, 2016

Unleashing the Guardian: The Targetable BCR-ABL/HAUSP/PML/PTEN Network in Chronic Myeloid Leukemia

Volume:18   Issue: 4
Pp: 389-395
Alessandro Morotti, Davide Torti, Giovanna Carra, Cristina Panuzzo, Sabrina Crivellaro, Riccardo Taulli, Carmen Fava, Angelo Guerrasio and Giuseppe Saglio
DOI: 10.2174/1389450117666160608120527
Published on: 08 June, 2016

Is Going for Cure in CML Targeting Aberrant Glycogen Synthase Kinase 3β?

Volume:18   Issue: 4
Pp: 396-404
Concetta Saponaro, Michele Maffia, Nicola Di Renzo and Addolorata Maria Luce Coluccia
DOI: 10.2174/1389450117666160817151723
Published on: 17 August, 2016

Stem Cell Guardians – Old and New Perspectives in LSC Biology

Volume:18   Issue: 4
Pp: 405-413
Gillian A. Horne, Lorna Jackson, Vignir Helgason and Tessa L. Holyoake
DOI: 10.2174/1389450117666160712092944
Published on: 11 July, 2016

Plant-derived Compounds as Potential Source of Novel Anti-Biofilm Agents Against Pseudomonas aeruginosa

Volume:18   Issue: 4
Pp: 414-420
Pooi Yin Chung
DOI: 10.2174/1389450117666161019102025
Published on: 18 October, 2016

Specific Targeting of Akt Kinase Isoforms: Taking the Precise Path for Prevention and Treatment of Cancer

Volume:18   Issue: 4
Pp: 421-435
Nand Kishor Roy, Devivasha Bordoloi, Javadi Monisha, Ganesan Padmavathi, Jibon Kotoky, Ramesh Golla and Ajaikumar B. Kunnumakkara
DOI: 10.2174/1389450117666160307145236
Published on: 07 March, 2016

Characterization and Management of Cutaneous Side Effects Related to the Immunosuppressive Treatment in Solid Organ Recipients

Volume:18   Issue: 4
Pp: 436-446
Paola Savoia, Andrea Ranghino and Paolo Fava
DOI: 10.2174/1389450117666160112115524
Published on: 11 January, 2016

The Hippo Pathway as Drug Targets in Cancer Therapy and Regenerative Medicine

Volume:18   Issue: 4
Pp: 447-454
Shunta Nagashima, Yijun Bao and Yutaka Hata
DOI: 10.2174/1389450117666160112115641
Published on: 11 January, 2016

ROCK in CNS: Different Roles of Isoforms and Therapeutic Target for Neurodegenerative Disorders

Volume:18   Issue: 4
Pp: 455-462
Cheong-Meng Chong, Nana Ai and Simon Ming-Yuen Lee
DOI: 10.2174/1389450117666160401123825
Published on: 01 April, 2016

MicroRNAs as Candidate Drug Targets for Cardiovascular Diseases

Volume:18   Issue: 4
Pp: 463-472
Pengzhou Hang, Jing Guo, Chuan Sun and Zhimin Du
DOI: 10.2174/1389450117666160301101221
Published on: 29 February, 2016

Sirtuins: Possible Clinical Implications in Cardio and Cerebrovascular Diseases

Volume:18   Issue: 4
Pp: 473-484
Valeria Conti, Maurizio Forte, Graziamaria Corbi, Giusy Russomanno, Luigi Formisano, Alessandro Landolfi, Viviana Izzo, Amelia Filippelli, Carmine Vecchione and Albino Carrizzo
DOI: 10.2174/1389450116666151019095903
Published on: 18 October, 2015

The Role of Gender-specific Cytokine Pathways as Drug Targets and Gender- specific Biomarkers in Personalized Cancer Therapy

Volume:18   Issue: 4
Pp: 485-495
Anna Maria Berghella, Ida Contasta, Roberto Lattanzio, Giancarlo Di Gregorio, Irma Campitelli, Marino Silvino, Luigi Liborio Liberatore, Luca Navarra, Giampaolo Caterino, Antonio Mongelli, Vincenzo Vittorini, Matteo Basta, Mauro Domenicucci, Nunzia Antonucci, Tiziana Del Beato, Enzo Secinaro, Fabiana Ciccone and Patrizia Pellegrini
DOI: 10.2174/1389450117666160630173647
Published on: 30 June, 2016