Current Drug Targets


Francis J. Castellino
(14643 citations)
Dean Emeritus, College of Science,
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Volume: 18 Issue: 15, December 2017

Editorial: New Therapetic Approaches in the Management of Ischemia Reperfusion Injury and Cardiometabolic Diseases: Opportunities and Challenges free to download

Volume:18   Issue: 15
Pp: 1687-1688
Jun Ren and Yingmei Zhang
DOI: 10.2174/138945011815171019092703
Published on: 18 October, 2017

New Pharmacological Approaches to the Prevention of Myocardial Ischemia- Reperfusion Injury

Volume:18   Issue: 15
Pp: 1689-1711
Kai Yee Chin, Chengxue Qin, Lauren May, Rebecca H. Ritchie and Owen L. Woodman*
DOI: 10.2174/1389450116666151001112020
Published on: 01 October, 2015

Progress in Therapies for Myocardial Ischemia Reperfusion Injury

Volume:18   Issue: 15
Pp: 1712-1721
Hong-jie Chi, Mu-lei Chen, Xin-chun Yang, Xiang-min Lin, Hao Sun, Wen-shu Zhao, Dan Qi, Jia-lu Dong and Jun Cai*
DOI: 10.2174/1389450117666160401120308
Published on: 01 April, 2016

Can microRNAs be Biomarkers or Targets for Therapy of Ischemic Coronary Artery Disease in Metabolic Syndrome?

Volume:18   Issue: 15
Pp: 1722-1732
Petra Rocic*
DOI: 10.2174/1389450117666160201113734
Published on: 31 January, 2016

Targeting Transient Receptor Potential Channels in Cardiometabolic Diseases and Myocardial Ischemia Reperfusion Injury

Volume:18   Issue: 15
Pp: 1733-1745
Jipeng Ma, Lifang Yang, Yanyan Ma, Xiaowu Wang, Jun Ren* and Jian Yang*
DOI: 10.2174/1389450116666151019102052
Published on: 18 October, 2015

SIRT1 as a Promising Novel Therapeutic Target for Myocardial Ischemia Reperfusion Injury and Cardiometabolic Disease

Volume:18   Issue: 15
Pp: 1746-1753
Dong Han, Jinda Wang, Sai Ma, Yundai Chen and Feng Cao*
DOI: 10.2174/1389450116666150630110529
Published on: 30 June, 2015

Targeting Interferon Regulatory Factor for Cardiometabolic Diseases: Opportunities and Challenges

Volume:18   Issue: 15
Pp: 1754-1778
Yaxing Zhang, Xiao-Jing Zhang and Hongliang Li*
DOI: 10.2174/1389450116666150804110412
Published on: 04 August, 2015

Targeting α7 Nicotinic Acetylcholine Receptor to Combat Inflammation in Cardio-Cerebral-Vascular Diseases

Volume:18   Issue: 15
Pp: 1779-1784
Hui Fu, Min Ni, Ji-Kuai Chen, Ting Zhao, Ya-Ping Deng, Dong-Jie Li, Guo-Jun Jiang* and Fu-Ming Shen*
DOI: 10.2174/1389450116666150825123247
Published on: 25 August, 2015

Targeting Apelinergic System in Cardiometabolic Disease

Volume:18   Issue: 15
Pp: 1785-1791
Rui Guo, Olivia Rogers and Sreejayan Nair*
DOI: 10.2174/1389450117666160613105152
Published on: 12 June, 2016

Roles of Insulin Resistance, Endothelial Dysfunction and Lifestyle Changes in the Development of Cardiovascular Disease in Diabetic Patients

Volume:18   Issue: 15
Pp: 1792-1799
Dongdong Sun, Wanrong Man and Lei Zhang*
DOI: 10.2174/1389450117666160715145518
Published on: 15 July, 2016

Cellular Repressor of E1A-stimulated Genes, A New Potential Therapeutic Target for Atherosclerosis

Volume:18   Issue: 15
Pp: 1800-1804
Xiaoxiang Tian, Chenghui Yan* and Yaling Han*
DOI: 10.2174/1389450117666161026111250
Published on: 26 October, 2016

Cardiac Tumors: Clinical Perspective and Therapeutic Considerations

Volume:18   Issue: 15
Pp: 1805-1809
Dylan Y. Ren, Nathan D. Fuller, Sara A.B. Gilbert and Yingmei Zhang*
DOI: 10.2174/1389450117666160703162111
Published on: 03 July, 2016

ALDH2---The Genetic Polymorphism and Enzymatic Activity Regulation: Their Epidemiologic and Clinical Implications

Volume:18   Issue: 15
Pp: 1810-1816
Rui Zhang, Jiali Wang, Mengyang Xue, Feng Xu* and Yuguo Chen*
DOI: 10.2174/1389450116666150727115118
Published on: 27 July, 2015

Aldehyde Dehydrogenase-2 Roles in Ischemic Cardiovascular Disease

Volume:18   Issue: 15
Pp: 1817-1823
Xiangwei Liu and Aijun Sun*
DOI: 10.2174/1389450117666160912174417
Published on: 12 September, 2016