Current Drug Targets


Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Volume:17   Issue: 9
Pp: 971-971
Martina Sanderson-Smith
DOI: 10.2174/138945011709160519204320

Editorial (Thematic Issue: From Extended Spectrum β-Lactamases to Carbapenemase: The Never Ending Challenge Against Gram-Negative Bacteria) free to download

Volume:17   Issue: 9
Pp: 972-973
Francesca Spyrakis
DOI: 10.2174/1389450116999151006095540

From “An Enzyme Able to Destroy Penicillin” to Carbapenemases: 70 Years of Beta-lactamase Misbehaviour

Volume:17   Issue: 9
Pp: 974-982
Jean-Marie Frère, Eric Sauvage and Frédéric Kerff
DOI: 10.2174/1389450116666151001112859

Decoding the Structural Basis For Carbapenem Hydrolysis By Class A β-lactamases: Fishing For A Pharmacophore

Volume:17   Issue: 9
Pp: 983-1005
Donatella Tondi, Simon Cross, Alberto Venturelli, Maria P. Costi, Gabriele Cruciani and Francesca Spyrakis
DOI: 10.2174/1389450116666151001104448

Structural and Functional Aspects of Class A Carbapenemases open access plus

Volume:17   Issue: 9
Pp: 1006-1028
Thierry Naas, Laurent Dortet and Bogdan I. Iorga
DOI: 10.2174/1389450117666160310144501

B1-Metallo-β-Lactamases: Where Do We Stand?

Volume:17   Issue: 9
Pp: 1029-1050
Maria F. Mojica, Robert A. Bonomo and Walter Fast
DOI: 10.2174/1389450116666151001105622

Structure-Function Relationships of Class D Carbapenemases

Volume:17   Issue: 9
Pp: 1061-1071
Jean-Denis Docquier and Stefano Mangani
DOI: 10.2174/1389450116666150825115824

MicroRNAs in Breast Cancer: One More Turn in Regulation

Volume:17   Issue: 9
Pp: 1083-1100
Pilar E. Asensio, Eduardo T. Martin, Begona P. Merlo, Estefanía E. Armas and Ana L. Hernández
DOI: 10.2174/1389450116666150213114103