Current Drug Targets


Francis J. Castellino
(14643 citations)
Dean Emeritus, College of Science,
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Volume: 17 Issue: 4, March 2016

Meet Our Editorial Board Member: free to download

Volume:17   Issue: 4
Pp: 375-375
Stefania Vetrano
DOI: 10.2174/138945011704160212092714
Published on: 11 February, 2016

Editorial (Thematic Issue: Therapeutic Modulators of Cellular Senescence: Common Targets in Cancer And Aging) free to download

Volume:17   Issue: 4
Pp: 376-376
Mauro Provinciali and Marco Malavolta
DOI: 10.2174/138945011704160212093659
Published on: 11 February, 2016

Morphological and Functional Characteristic of Senescent Cancer Cells

Volume:17   Issue: 4
Pp: 377-387
Ewa Sikora, Grazyna Mosieniak and Malgorzata Alicja Sliwinska
DOI: 10.2174/1389450116666151019094724
Published on: 18 October, 2015

Endothelial Cell Senescence and Inflammaging: MicroRNAs as Biomarkers and Innovative Therapeutic Tools

Volume:17   Issue: 4
Pp: 388-397
Francesco Prattichizzo, Massimiliano Bonafè, Artan Ceka, Angelica Giuliani, Maria Rita Rippo, Massimo Re, Roberto Antonicelli, Antonio Domenico Procopio and Fabiola Olivieri
DOI: 10.2174/1389450116666150804105659
Published on: 03 August, 2015

Stress Hormone-Mediated DNA Damage Response -- Implications for Cellular Senescence and Tumour Progression

Volume:17   Issue: 4
Pp: 398-404
María Moreno-Villanueva and Alexander Bürkle
DOI: 10.2174/1389450116666151001113720
Published on: 30 September, 2015

Roles of Apoptosis and Cellular Senescence in Cancer and Aging

Volume:17   Issue: 4
Pp: 405-415
Claudia Cerella, Cindy Grandjenette, Mario Dicato and Marc Diederich
DOI: 10.2174/1389450116666150202155915
Published on: 02 February, 2015

Endogenous Retroelements in Cellular Senescence and Related Pathogenic Processes: Promising Drug Targets in Age-Related Diseases

Volume:17   Issue: 4
Pp: 416-427
Maurizio Cardelli, Robertina Giacconi, Marco Malavolta and Mauro Provinciali
DOI: 10.2174/1389450116666150518095829
Published on: 17 May, 2015

The Impact of the Emerging Genomics Data on the Management of Agerelated Phenotypes in the Context of Cellular Senescence

Volume:17   Issue: 4
Pp: 428-438
Alberto Montesanto, Silvana Geracitano, Sabrina Garasto, Sergio Fusco, Fabrizia Lattanzio, Giuseppe Passarino and Andrea Corsonello
DOI: 10.2174/1389450116666150120103329
Published on: 19 January, 2015

Pleiotropic Effects of Tocotrienols and Quercetin on Cellular Senescence: Introducing the Perspective of Senolytic Effects of Phytochemicals

Volume:17   Issue: 4
Pp: 447-459
Marco Malavolta, Elisa Pierpaoli, Robertina Giacconi, Laura Costarelli, Francesco Piacenza, Andrea Basso, Maurizio Cardelli and Mauro Provinciali
DOI: 10.2174/1389450116666150907105104
Published on: 06 September, 2015

Is Senescence Reversible?

Volume:17   Issue: 4
Pp: 460-466
Shweta Chakradeo, Lynne W. Elmore and David A. Gewirtz
DOI: 10.2174/1389450116666150825113500
Published on: 24 August, 2015

Targeted Drug Delivery for Cardiovascular and Cerebrovascular Diseases

Volume:17   Issue: 4
Pp: 467-474
Jingjing Luan and Guangxi Zhai
DOI: 10.2174/1389450116666150416120224
Published on: 16 April, 2015

The Key Role of Canonical Wnt/β-catenin Signaling in Cartilage Chondrocytes

Volume:17   Issue: 4
Pp: 475-484
Xiaoliang Yuan, Haiqing Liu, Hao Huang, Hai Liu, Linfu Li, Jianqiong Yang, Weimei Shi, Weiyou Liu and Longhuo Wu
DOI: 10.2174/1389450116666150825112623
Published on: 24 August, 2015