Current Drug Targets


Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Phosphorothioate Oligonucleotides: Effectiveness and Toxicity

Volume:15   Issue: 7
Pp: 663-673
Tommaso Iannitti, Julio Cesar Morales-Medina and Beniamino Palmieri
DOI: 10.2174/1389450115666140321100304
Published on: 01 June, 2014

The Synergistic Effect of Humanized Monoclonal Antibodies Targeting Insulin-Like Growth Factor 1 Receptor (IGF-1R) and Chemotherapy

Volume:15   Issue: 7
Pp: 674-680
Ping Sui, Hongxin Cao, Long Meng, Pingping Hu, Honghai Ma and Jiajun Du
DOI: 10.2174/1389450115666140526154642
Published on: 01 June, 2014

Fused Aryl-Phenazines: Scaffold for the Development of Bioactive Molecules

Volume:15   Issue: 7
Pp: 681-688
N.S. Hari Narayana Moorthy, Vijayakumari Pratheepa, Maria J. Ramos, Vitor Vasconcelos and Pedro A. Fernandes
DOI: 10.2174/1389450115666140205152007
Published on: 01 June, 2014

Beneficial Effects of Selective Vitamin D Receptor Activation by Paricalcitol in Chronic Kidney Disease

Volume:15   Issue: 7
Pp: 703-709
Javier Donate-Correa, Virginia Domínguez-Pimentel, Mercedes Muros-de-Fuentes, Carmen Mora-Fernández, Ernesto Martín-Nunez, Violeta Cazana-Perez and Juan F. Navarro-González
DOI: 10.2174/1389450115666140417120902
Published on: 01 June, 2014

Mitochondrial Pathology in Osteoarthritic Chondrocytes

Volume:15   Issue: 7
Pp: 710-719
Longhuo Wu, Haiqing Liu, Linfu Li, Hai Liu, Qilai Cheng, Hongliang Li and Hao Huang
DOI: 10.2174/1389450115666140417120305
Published on: 01 June, 2014

The Role of P2Y12 Receptor and Activated Platelets During Inflammation

Volume:15   Issue: 7
Pp: 720-728
Elisabetta Liverani, Laurie E. Kilpatrick, Alexander Y. Tsygankov and Satya P. Kunapuli
DOI: 10.2174/1389450115666140519162133
Published on: 01 June, 2014

Supramolecular Chiro-Biomedical Aspect of β-Blockers in Drug Development

Volume:15   Issue: 7
Pp: 729-741
Imran Ali, Ashanul Haque, Mohamed F. Al Ajmi, Afzal Hussain, Mohd Marsin Sanagi, Iqbal Hussain and Hassan Y. Aboul-Enein
DOI: 10.2174/1389450115666140429104516
Published on: 01 June, 2014