Current Drug Targets


Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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MicroRNA-34a: Role in Cancer and Cardiovascular Disease

Volume:15   Issue: 4
Pp: 361-373
Xi Chen, Jian-Ya Zhou and Jian-Ying Zhou
DOI: 10.2174/1389450115666140120102935
Published on: 10 March, 2014

Antimalarial Drug Targets and Drugs Targeting Dolichol Metabolic Pathway of Plasmodium falciparum

Volume:15   Issue: 4
Pp: 374-409
Tabish Qidwai, Avantika Priya, Nihal Ahmad Khan, Himanshu Tripathi, Feroz Khan, Mahendra Pandurang Darokar, Anirban Pal, Dnyneshwar U. Bawankule, Rakesh Kumar Shukla and Rajendra Singh Bhakuni
DOI: 10.2174/13894501113149990169
Published on: 10 March, 2014

5-Lipoxygenase: A Promising Drug Target Against Inflammatory Diseases-Biochemical and Pharmacological Regulation

Volume:15   Issue: 4
Pp: 410-422
Yasir Anwar, Jamal S.M. Sabir, Muhammad I. Qureshi and Kulvinder S. Saini
DOI: 10.2174/1389450114666131209110745
Published on: 10 March, 2014

Hsp27 as a Therapeutic Target in Cancers

Volume:15   Issue: 4
Pp: 423-431
Julie Acunzo, Claudia Andrieu, Virginie Baylot, Alan So and Palma Rocchi
DOI: 10.2174/13894501113146660230
Published on: 10 March, 2014

Down Regulation of Differentiated Embryo-Chondrocyte Expressed Gene 1 is Related to the Decrease of Osteogenic Capacity

Volume:15   Issue: 4
Pp: 432-441
Hu Jinhua, Mao Zhao, Shang Wei, Yue Haitao, Wang Yuwen, Wu Lili, Liu Wei and Yang Jian
DOI: 10.2174/1389450114666140102133719
Published on: 10 March, 2014

Impact of Matrix Metalloproteinases on Atherosclerosis

Volume:15   Issue: 4
Pp: 442-453
Juntang Lin, Vijay Kakkar and Xinjie Lu
DOI: 10.2174/1389450115666140211115805
Published on: 10 March, 2014

The Role of Oxidative Stress in Huntington’s Disease: Are Antioxidants Good Therapeutic Candidates?

Volume:15   Issue: 4
Pp: 454-468
Joana Gil-Mohapel, Patricia S. Brocardo and Brian R. Christie
DOI: 10.2174/1389450115666140115113734
Published on: 10 March, 2014

The Role of Anti-LeY Antibody in the Downregulation of MAPKs/COX-2 Pathway in Gastric Cancer

Volume:15   Issue: 4
Pp: 469-476
Faisal Aziz and Yan Qiu
DOI: 10.2174/1389450115666140217152042
Published on: 10 March, 2014