Current Drug Targets


Francis J. Castellino
(14643 citations)
Dean Emeritus, College of Science,
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Volume: 14 Issue: 11, October 2013

Editorial (Thematic Issue: Glia: A New Cellular Target in the Treatment of Major Depression) free to download

Volume:14   Issue: 11
Pp: 1219-1219
Bruno Guiard
DOI: 10.2174/13894501113149990207
Published on: 17 September, 2013

Astrocyte-Neuron Interaction at Tripartite Synapses

Volume:14   Issue: 11
Pp: 1220-1224
Alberto Pérez-Alvarez and Alfonso Araque
DOI: 10.2174/13894501113149990203
Published on: 17 September, 2013

Astrocyte Pathology in Major Depressive Disorder: Insights from Human Postmortem Brain Tissue

Volume:14   Issue: 11
Pp: 1225-1236
Grazyna Rajkowska and Craig A. Stockmeier
DOI: 10.2174/13894501113149990156
Published on: 17 September, 2013

Serum S100B Represents a New Biomarker for Mood Disorders open access plus

Volume:14   Issue: 11
Pp: 1237-1248
Matthias L. Schroeter, Julia Sacher, Johann Steiner, Peter Schoenknecht and Karsten Mueller
DOI: 10.2174/13894501113149990014
Published on: 17 September, 2013

Altered Glial Plasticity in Animal Models for Mood Disorders

Volume:14   Issue: 11
Pp: 1249-1261
Boldizsár Czéh, Eberhard Fuchs and Gabriele Flügge
DOI: 10.2174/1389450111314110005
Published on: 17 September, 2013

Acute and Chronic Stress-Induced Disturbances of Microglial Plasticity, Phenotype and Function open access plus

Volume:14   Issue: 11
Pp: 1262-1276
Frederick Rohan Walker, Michael Nilsson and Kimberley Jones
DOI: 10.2174/13894501113149990208
Published on: 29 August, 2013

The Monoaminergic Tripartite Synapse: A Putative Target for Currently Available Antidepressant Drugs

Volume:14   Issue: 11
Pp: 1277-1294
Gaël Quesseveur, Alain M. Gardier and Bruno P. Guiard
DOI: 10.2174/13894501113149990209
Published on: 29 August, 2013

Astrocytes and Gliotransmitters: New Players in the Treatment of Major Depression?

Volume:14   Issue: 11
Pp: 1295-1307
Adeline Etiévant, Laura Lambás-Señas, Hélène Scarna, Guillaume Lucas and Nasser Haddjeri
DOI: 10.2174/13894501113149990197
Published on: 22 July, 2013

Regulation of Neurotrophic Factors and Energy Metabolism by Antidepressants in Astrocytes

Volume:14   Issue: 11
Pp: 1308-1321
Jean-Luc Martin, Pierre J. Magistretti and Igor Allaman
DOI: 10.2174/1389450111314110009
Published on: 17 September, 2013

Glia: An Important Target for Anti-Inflammatory and Antidepressant Activity

Volume:14   Issue: 11
Pp: 1322-1328
Sadayuki Hashioka, Tsuyoshi Miyaoka, Rei Wake, Motohide Furuya and Jun Horiguchi
DOI: 10.2174/13894501113146660214
Published on: 10 September, 2013

Talking to the Synapse: How Antidepressants Can Target Glial Cells to Reshape Brain Circuits

Volume:14   Issue: 11
Pp: 1329-1335
Barbara Di Benedetto, Rainer Rupprecht and Boldizsár Czéh
DOI: 10.2174/1389450111314110011
Published on: 17 September, 2013

Lentiviral Vectors: A Powerful Tool to Target Astrocytes In Vivo

Volume:14   Issue: 11
Pp: 1336-1346
Delzor Aurélie, Escartin Carole and Déglon Nicole
DOI: 10.2174/13894501113146660213
Published on: 10 September, 2013

Molecular Mechanisms and Treatment of Radiation-Induced Lung Fibrosis open access plus

Volume:14   Issue: 11
Pp: 1347-1356
Nian-Hua Ding, Jian Jian Li and Lun-Quan Sun
DOI: 10.2174/13894501113149990198
Published on: 30 July, 2013

25-(OH)VitD3, as a Risk Indicator in Diagnosis of Adenocarcinoma

Volume:14   Issue: 11
Pp: 1367-1376
Liang-Liang Cai, Hui-Ming Ye, Xiao-Nan Lv, Yun-long Wu, Huan-Jing Zhang, Li-Mou Zheng and Chi-Meng Tzeng
DOI: 10.2174/13894501113149990204
Published on: 20 August, 2013