Current Drug Targets


Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Editorial (Hot Topic: MiRNAs as Legitimate Targets for Cancer Therapy) free to download

Volume:14   Issue: 10
Pp: 1093-1093
Zhiwei Wang
DOI: 10.2174/1389450111314100001

Nuclear Export Mediated Regulation of MicroRNAs: Potential Target for Drug Intervention

Volume:14   Issue: 10
Pp: 1094-1100
Irfana Muqbil, Bin Bao, Abdul Badi Abou-Samra, Ramzi M. Mohammad and Asfar S. Azmi
DOI: 10.2174/1389450111314100002

Prospects of miRNA-Based Therapy for Pancreatic Cancer

Volume:14   Issue: 10
Pp: 1101-1109
Priya Pai, Satyanarayana Rachagani, Chandrakanth Are and Surinder K. Batra
DOI: 10.2174/13894501113149990181

Function of miRNA in Controlling Drug Resistance of Human Cancers

Volume:14   Issue: 10
Pp: 1118-1127
Liu Hong, Zhiping Yang, Jiaojiao Ma and Daiming Fan
DOI: 10.2174/13894501113149990183

MicroRNAs in Skin Response to UV Radiation

Volume:14   Issue: 10
Pp: 1128-1134
Deeba N. Syed, Mohammad Imran Khan, Maria Shabbir and Hasan Mukhtar
DOI: 10.2174/13894501113149990184

Targeting miR-21 Induces Autophagy and Chemosensitivity of Leukemia Cells

Volume:14   Issue: 10
Pp: 1135-1143
Hugo Seca, Raquel T. Lima, Vanessa Lopes-Rodrigues, Jose E. Guimaraes, Gabriela M. Gabriela and M. Helena Vasconcelos
DOI: 10.2174/13894501113149990185

From Target Therapy to miRNA Therapeutics of Human Multiple Myeloma: Theoretical and Technological Issues in the Evolving Scenario

Volume:14   Issue: 10
Pp: 1144-1149
Marco Rossi, Nicola Amodio, Maria Teresa Di Martino, Daniele Caracciolo, Pierosandro Tagliaferri and Pierfrancesco Tassone
DOI: 10.2174/13894501113149990186

Genistein Down-Regulates miR-223 Expression in Pancreatic Cancer Cells

Volume:14   Issue: 10
Pp: 1150-1156
Jia Ma, Long Cheng, Hao Liu, Jing Zhang, Ying Shi, Fanpeng Zeng, Lucio Miele, Fazlul H Sarkar, Jun Xia and Zhiwei Wang
DOI: 10.2174/13894501113149990187

Notch-Associated MicroRNAs in Cancer

Volume:14   Issue: 10
Pp: 1157-1166
Yin-Yuan Mo, Hua Tang and Lucio Miele
DOI: 10.2174/13894501113149990188

Regulating miRNA by Natural Agents as a New Strategy for Cancer Treatment

Volume:14   Issue: 10
Pp: 1167-1174
Sajiv Sethi, Yiwei Li and Fazlul H. Sarkar
DOI: 10.2174/13894501113149990189

Cancer “Stemness”- Regulating MicroRNAs: Role, Mechanisms and Therapeutic Potential

Volume:14   Issue: 10
Pp: 1175-1184
Arun Bhardwaj, Sumit Arora, Vijay K. Prajapati, Seema Singh and Ajay P. Singh
DOI: 10.2174/13894501113149990190

Functional Role of miR-34 Family in Human Cancer

Volume:14   Issue: 10
Pp: 1185-1191
Rui Wang, Jia Ma, Qiong Wu, Jun Xia, Lucio Miele, Fazlul H Sarkar and Zhiwei Wang
DOI: 10.2174/13894501113149990191

Signaling of MiRNAs-FOXM1 in Cancer and Potential Targeted Therapy

Volume:14   Issue: 10
Pp: 1192-1202
Min Shi, Jiujie Cui and Keping Xie
DOI: 10.2174/13894501113149990192

Nociceptin / Orphanin FQ (NOP) Receptors as Novel Potential Target in the Treatment of Gastrointestinal Diseases

Volume:14   Issue: 10
Pp: 1203-1209
Marta Sobczak, Maciej Saaga, Martin Storr and Jakub Fichna
DOI: 10.2174/13894501113149990174

Curcumin: A Boon to Colonic Diseases

Volume:14   Issue: 10
Pp: 1210-1218
Rashmi Sareen, Nitin Jain and Vinay Pandit
DOI: 10.2174/13894501113149990168