Current Drug Targets


Francis J. Castellino
(14643 citations)
Dean Emeritus, College of Science,
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Volume: 14 Issue: 1, January 2012

Editorial (Hot Topic: Neuroprotection and Neuroregeneration in Ischemic Stroke: Emerging Treatment Strategies and Potential Molecular Targets)

Volume:14   Issue: 1
Pp: 1-2
G. K. Rajanikant
DOI: 10.2174/1389450111314010001
Published on: 28 December, 2012

Stroke Prevention: From Available Antiplatelet Drugs to Novel Molecular Targets

Volume:14   Issue: 1
Pp: 3-12
Matteo Nicola Dario Di Minno, Stefania Momi, Alessandro Di Minno and Anna Russolillo
DOI: 10.2174/1389450111314010002
Published on: 28 December, 2012

Oxidation Inhibits Iron-Induced Blood Coagulation open access plus

Volume:14   Issue: 1
Pp: 13-19
Etheresia Pretorius, Janette Bester, Natasha Vermeulen and Boguslaw Lipinski
DOI: 10.2174/1389450111314010003
Published on: 28 December, 2012

Global Cerebral Ischemia: Synaptic and Cognitive Dysfunction

Volume:14   Issue: 1
Pp: 20-35
Jake T. Neumann, Charles H. Cohan, Kunjan R. Dave, Clinton B. Wright and Miguel A. Perez-Pinzon
DOI: 10.2174/1389450111314010004
Published on: 28 December, 2012

A Key Role for Connexin Hemichannels in Spreading Ischemic Brain Injury

Volume:14   Issue: 1
Pp: 36-46
Joanne O. Davidson, Colin R. Green, Laura Bennet, Louise F.B. Nicholson, Helen Danesh-Meyer, Simon J. O’Carroll and Alistair J. Gunn
DOI: 10.2174/1389450111314010005
Published on: 28 December, 2012

Minocycline Mediated Mitochondrial Cytoprotection: Premises for Therapy of Cerebrovascular and Neurodegenerative Diseases

Volume:14   Issue: 1
Pp: 47-55
Andonis Karachitos, Julian Solis Garcia del Pozo, Piet W.J. de Groot, Hanna Kmita and Joaquin Jordan
DOI: 10.2174/1389450111314010006
Published on: 28 December, 2012

Inhalation Gases or Gaseous Mediators As Neuroprotectants for Cerebral Ischaemia

Volume:14   Issue: 1
Pp: 56-73
Brad A. Sutherland, Joanne C. Harrison, Shiva M. Nair and Ivan A. Sammut
DOI: 10.2174/1389450111314010007
Published on: 28 December, 2012

Neuroprotection & Mechanism of Ethanol in Stroke and Traumatic Brain Injury Therapy: New Prospects for an Ancient Drug

Volume:14   Issue: 1
Pp: 74-80
Karam Asmaro, Paul Fu and Yuchuan Ding
DOI: 10.2174/1389450111314010008
Published on: 28 December, 2012

Stem Cell-Mediated Gene Delivering for the Treatment of Cerebral Ischemia: Progress and Prospectives

Volume:14   Issue: 1
Pp: 81-89
Chao Chen, Yongting Wang and Guo-Yuan Yang
DOI: 10.2174/1389450111314010009
Published on: 28 December, 2012

microRNAs: Innovative Targets for Cerebral Ischemia and Stroke

Volume:14   Issue: 1
Pp: 90-101
Yi-Bing Ouyang, Creed M. Stary, Guo-Yuan Yang and Rona Giffard
DOI: 10.2174/1389450111314010010
Published on: 28 December, 2012

Human Ether-a-Go-Go-Related Gene Channel Blockers and its Structural Analysis for Drug Design

Volume:14   Issue: 1
Pp: 102-113
N. S. Hari Narayana Moorthy, Maria J. Ramos and Pedro A. Fernandes
DOI: 10.2174/1389450111314010011
Published on: 28 December, 2012

Molecular Mechanism Aspect of ER Stress in Alzheimer's Disease: Current Approaches and Future Strategies

Volume:14   Issue: 1
Pp: 114-122
Niloufar Ansari and Fariba Khodagholi
DOI: 10.2174/1389450111314010012
Published on: 28 December, 2012

Colloidal Drug Delivery Systems in Vaccine Delivery

Volume:14   Issue: 1
Pp: 123-137
Sarwar Beg, Abdus Samad, Iram Nazish, Ruksar Sultana, Mahfoozur Rahman, Md Zaki Ahmad and Md Akbar
DOI: 10.2174/1389450111314010013
Published on: 28 December, 2012