Current Drug Targets


Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Editorial (Hot Topic: Natural Products as Anti-Cancer Agents: Understanding their Mechanism of Action) promotion: free to download

Volume:13   Issue: 8
Pp: 1005-1005
Francesco Epifano
DOI: 10.2174/138945012802009071
Published on: 11 June, 2012

Pro-Oxidant Natural Products as Anticancer Agents

Volume:13   Issue: 8
Pp: 1006-1028
Carmen Martin-Cordero, Antonio Jose Leon-Gonzalez, Jose Manuel Calderon-Montano, Estefania Burgos-Moron and Miguel Lopez-Lazaro
DOI: 10.2174/138945012802009044
Published on: 11 June, 2012

Discovery and Mechanism of Natural Products as Modulators of Histone Acetylation

Volume:13   Issue: 8
Pp: 1029-1047
Lilibeth A. Salvador and Hendrik Luesch
DOI: 10.2174/138945012802008973
Published on: 11 June, 2012

New Anticancer Drugs from Marine Cyanobacteria

Volume:13   Issue: 8
Pp: 1048-1053
Patrizia Russo and Alfredo Cesario
DOI: 10.2174/138945012802009035
Published on: 11 June, 2012

Targeting Cancer Stem Cells with Natural Products

Volume:13   Issue: 8
Pp: 1054-1064
Joseph Burnett, Bryan Newman and Duxin Sun
DOI: 10.2174/138945012802009062
Published on: 11 June, 2012

Vinorelbine in Cancer Therapy

Volume:13   Issue: 8
Pp: 1065-1071
Anna Capasso
DOI: 10.2174/138945012802009017
Published on: 11 June, 2012

Seek and Destroy: The Use of Natural Compounds for Targeting the Molecular Roots of Cancer

Volume:13   Issue: 8
Pp: 1072-1082
Ana C.S. Souza, Angelo de Fatima, Rafael B. da Silveira and Giselle Z. Justo
DOI: 10.2174/138945012802008991
Published on: 11 June, 2012

Recent Developments in the Pharmacological Properties of 4'-Geranyloxyferulic Acid, a Colon Cancer Chemopreventive Agent of Natural Origin

Volume:13   Issue: 8
Pp: 1083-1088
Salvatore Genovese and Francesco Epifano
DOI: 10.2174/138945012802009008
Published on: 11 June, 2012

TRAIL as Biomarker and Potential Therapeutic Tool for Cardiovascular Diseases

Volume:13   Issue: 8
Pp: 1089-1095
Stella Bernardi, Daniela Milani, Bruno Fabris, Paola Secchiero and Giorgio Zauli
DOI: 10.2174/138945012802008982
Published on: 11 June, 2012

Novel Chelators Targeting Cell Cycle Arrest, Acetylcholinesterase, and Monoamine Oxidase for Alzheimer's Therapy

Volume:13   Issue: 8
Pp: 1096-1113
Hailin Zheng, Mati Fridkin and Moussa B.H. Youdim
DOI: 10.2174/138945012802009026
Published on: 11 June, 2012

Leukotriene C4 Synthase: Upcoming Drug Target For Inflammation

Volume:13   Issue: 8
Pp: 1114-1125
Nisha S. Devi and Mukesh Doble
DOI: 10.2174/138945012802009053
Published on: 11 June, 2012