Current Drug Targets


Francis J. Castellino
(14643 citations)
Dean Emeritus, College of Science,
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Volume: 13 Issue: 4, April

Editorial [Hot Topic: Comparative Biochemistry of Molecular Targets for Drug and Pesticides: N-Acetyl-D-glucosamine and Acetylcholine Related Enzymes (Guest Editor: Qing Yang )]

Volume:13   Issue: 4
Pp: 441-441
Qing Yang
DOI: 10.2174/138945012799499776
Published on: 01 March, 2012

Chitin-Related Enzymes in Agro-Biosciences

Volume:13   Issue: 4
Pp: 442-470
Yasuyuki Arakane, Toki Taira, Takayuki Ohnuma and Tamo Fukamizo
DOI: 10.2174/138945012799499721
Published on: 01 March, 2012

Novel and Viable Acetylcholinesterase Target Site for Developing Effective and Environmentally Safe Insecticides open access plus

Volume:13   Issue: 4
Pp: 471-482
Yuan-Ping Pang, Stephen Brimijoin, David W. Ragsdale, Kun Yan Zhu and Robert Suranyi
DOI: 10.2174/138945012799499703
Published on: 01 March, 2012

Ladostigil: A Novel Multimodal Neuroprotective Drug with Cholinesterase and Brain-Selective Monoamine Oxidase Inhibitory Activities for Alzheimers Disease Treatment

Volume:13   Issue: 4
Pp: 483-494
Orly Weinreb, Tamar Amit, Orit Bar-Am and Moussa B.H. Youdim
DOI: 10.2174/138945012799499794
Published on: 01 March, 2012

Can Acetylcholinesterase Serve as a Target for Developing More Selective Insecticides?

Volume:13   Issue: 4
Pp: 495-501
Guo-Jun Lang, Kun Yan Zhu and Chuan-Xi Zhang
DOI: 10.2174/138945012799499712
Published on: 01 March, 2012

Investigation of Family 18 Chitinases and Inhibitors by Computer-Aided Approaches

Volume:13   Issue: 4
Pp: 502-511
Huiying Chu, Jinan Wang, Hujun Shen, Yongliang Yang, Weiliang Zhu and Guohui Li
DOI: 10.2174/138945012799499695
Published on: 01 March, 2012

Advanced Glycation End Products as Environmental Risk Factors for the Development of Type 1 Diabetes

Volume:13   Issue: 4
Pp: 526-540
Felicia Y.T. Yap, Phillip Kantharidis, Melinda T. Coughlan, Robyn Slattery and Josephine M. Forbes
DOI: 10.2174/138945012799499758
Published on: 01 March, 2012

Molecular Profiling - An Essential Technology Enabling Personalized Medicine in Breast Cancer

Volume:13   Issue: 4
Pp: 541-554
Jiangang Liu, Shuyu Li, A. Keith Dunker and Vladimir N. Uversky
DOI: 10.2174/138945012799499767
Published on: 01 March, 2012

Long-Acting Antipsychotic Medications

Volume:13   Issue: 4
Pp: 555-560
Raman Baweja, Karim Sedky and Steven Lippmann
DOI: 10.2174/138945012799499785
Published on: 01 March, 2012

Molecular Targeting Regulation of Proliferation and Differentiation of the Bone Marrow-Derived Mesenchymal Stem Cells or Mesenchymal Stromal Cells

Volume:13   Issue: 4
Pp: 561-571
Bei-Yu Chen, Xi Wang, Liang-Wei Chen and Zhuo-Jing Luo
DOI: 10.2174/138945012799499749
Published on: 01 March, 2012