Current Drug Targets


Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Editorial (Hot Topic: Translational Implications of Natural Agents) free to download

Volume:13   Issue: 14
Pp: 1687-1688
KM Wahidur Rahman
DOI: 10.2174/138945012804545605

Single Dose Oral Pharmacokinetic Profile of α-Mangostin in Mice

Volume:13   Issue: 14
Pp: 1698-1704
Atulkumar Ramaiya, Gongbo Li, Sakina M. Petiwala and Jeremy J. Johnson
DOI: 10.2174/138945012804545524

Indole Compounds Against Breast Cancer: Recent Developments

Volume:13   Issue: 14
Pp: 1705-1719
Bernhard Biersack and Rainer Schobert
DOI: 10.2174/138945012804545551

Anticarcinogenic Actions of Tributyrin, A Butyric Acid Prodrug

Volume:13   Issue: 14
Pp: 1720-1729
Renato Heidor, Juliana Festa Ortega, Aline de Conti, Thomas Prates Ong and Fernando Salvador Moreno
DOI: 10.2174/138945012804545443

Ent-11α-Hydroxy-15-Oxo-Kaur-16-en-19-Oic-Acid Induces Apoptosis of Human Malignant Cancer Cells

Volume:13   Issue: 14
Pp: 1730-1737
Ming-Yue Li, Nian Ci Liang and George G. Chen
DOI: 10.2174/138945012804545623

A Prooxidant Mechanism for the Anticancer and Chemopreventive Properties of Plant Polyphenols

Volume:13   Issue: 14
Pp: 1738-1749
Husain Yar Khan, Haseeb Zubair, Mohd Fahad Ullah, Aamir Ahmad and Sheikh Mumtaz Hadi
DOI: 10.2174/138945012804545560

Genistein Inhibits Cell Growth and Induces Apoptosis Through Up-regulation of miR-34a in Pancreatic Cancer Cells

Volume:13   Issue: 14
Pp: 1750-1756
Jun Xia, Qiaoling Duan, Aamir Ahmad, Bin Bao, Sanjeev Banerjee, Ying Shi, Jia Ma, Jian Geng, Zhiwen Chen, KM Wahidur Rahman, Lucio Miele, Fazlul H Sarkar and Zhiwei Wang
DOI: 10.2174/138945012804545597

Ascorbic Acid in Cancer Chemoprevention: Translational Perspectives and Efficacy

Volume:13   Issue: 14
Pp: 1757-1771
Mohammad F. Ullah, Showket H. Bhat, Eram Hussain, Faisel Abu-Duhier, Aamir Ahmad and S. M. Hadi
DOI: 10.2174/138945012804545669

Baicalein - An Intriguing Therapeutic Phytochemical in Pancreatic Cancer

Volume:13   Issue: 14
Pp: 1772-1776
Graham Donald, Kathleen Hertzer and Guido Eibl
DOI: 10.2174/138945012804545470

From Body Art to Anticancer Activities: Perspectives on Medicinal Properties of Henna

Volume:13   Issue: 14
Pp: 1777-1798
Rohan Pradhan, Prasad Dandawate, Alok Vyas, Subhash Padhye, Bernhard Biersack, Rainer Schobert, Aamir Ahmad and Fazlul H. Sarkar
DOI: 10.2174/138945012804545588

Chemopreventive and Chemotherapeutic Potential of Curcumin in Breast Cancer

Volume:13   Issue: 14
Pp: 1799-1819
Dona Sinha, Jaydip Biswas, Bokyung Sung, Bharat B. Aggarwal and Anupam Bishayee
DOI: 10.2174/138945012804545632

Mitosis-Targeting Natural Products for Cancer Prevention and Therapy

Volume:13   Issue: 14
Pp: 1820-1830
Chinthalapally V. Rao, Carla D. Kurkjian and Hiroshi Y. Yamada
DOI: 10.2174/138945012804545533

Apoptosis and Autophagy Induction As Mechanism of Cancer Prevention by Naturally Occurring Dietary Agents

Volume:13   Issue: 14
Pp: 1831-1841
Eiman Mukhtar, Vaqar Mustafa Adhami, Naghma Khan and Hasan Mukhtar
DOI: 10.2174/138945012804545489

Cancer Chemoprevention with Green Tea Catechins: From Bench to Bed

Volume:13   Issue: 14
Pp: 1842-1857
Yohei Shirakami, Masahito Shimizu and Hisataka Moriwaki
DOI: 10.2174/138945012804545506

Targeting CSC-Related miRNAs for Cancer Therapy by Natural Agents

Volume:13   Issue: 14
Pp: 1858-1868
Bin Bao, Yiwei Li, Aamir Ahmad, Asfar S. Azmi, Ginny Bao, Shadan Ali, Sanjeev Banerjee, Dejuan Kong and Fazlul H. Sarkar
DOI: 10.2174/138945012804545515

DIMming Ovarian Cancer Growth

Volume:13   Issue: 14
Pp: 1869-1875
Prabodh K. Kandala and Sanjay K. Srivastava
DOI: 10.2174/138945012804545650

Bioavailability Challenges Associated with Development of Saponins As Therapeutic and Chemopreventive Agents

Volume:13   Issue: 14
Pp: 1885-1899
Song Gao, Sumit Basu, Zhen Yang, Arijita Deb and Ming Hu
DOI: 10.2174/138945012804545498

Medicinal Properties of the Jamaican Pepper Plant Pimenta dioica and Allspice

Volume:13   Issue: 14
Pp: 1900-1906
Lei Zhang and Bal L. Lokeshwar
DOI: 10.2174/138945012804545641

Androgen Receptor in Human Health: A Potential Therapeutic Target

Volume:13   Issue: 14
Pp: 1907-1916
Hifzur Rahman Siddique, Sanjeev Nanda, Aijaz Parray and Mohammad Saleem
DOI: 10.2174/138945012804545579

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Volume:13   Issue: 14
Pp: 1926-1927

DOI: 10.2174/138945012804545542