Current Drug Targets


Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556

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Editorial: [Hot Topic: Establishment of the Australian Infectious Diseases Research Centre] free to download

Volume:13   Issue: 11
Pp: 1347-1347
Mark Walker
DOI: 10.2174/138945012803530189
Published on: 22 August, 2012

TargetingQuorum Sensing and Competence Stimulation for Antimicrobial Chemotherapy

Volume:13   Issue: 11
Pp: 1348-1359
Nicholas E. Shepherd, Rosemary S. Harrison and David P. Fairlie
DOI: 10.2174/138945012803530233
Published on: 22 August, 2012

Adaptors in Toll-Like Receptor Signaling and their Potential as Therapeutic Targets

Volume:13   Issue: 11
Pp: 1360-1374
Thomas Ve, Nicholas J. Gay, Ashley Mansell, Bostjan Kobe and Stuart Kellie
DOI: 10.2174/138945012803530260
Published on: 22 August, 2012

Resolving Biofilm Infections: Current Therapy and Drug Discovery Strategies

Volume:13   Issue: 11
Pp: 1375-1385
Max V. Ranall, Mark S. Butler, Mark A. Blaskovich and Matthew A. Cooper
DOI: 10.2174/138945012803530251
Published on: 22 August, 2012

Uropathogenic Escherichia coli Mediated Urinary Tract Infection

Volume:13   Issue: 11
Pp: 1386-1399
Makrina Totsika, Danilo Gomes Moriel, Adi Idris, Benjamin A. Rogers, Daniel J. Wurpel, Minh-Duy Phan, David L. Paterson and Mark A. Schembri
DOI: 10.2174/138945012803530206
Published on: 22 August, 2012

Prokaryotic Substrate-Binding Proteins as Targets for Antimicrobial Therapies

Volume:13   Issue: 11
Pp: 1400-1410
Rafael M. Counago, Christopher A. McDevitt, Miranda P. Ween and Bostjan Kobe
DOI: 10.2174/138945012803530170
Published on: 22 August, 2012

RNA Interference for Viral Infections

Volume:13   Issue: 11
Pp: 1411-1420
Stephen J. Blake, Fawzi F. Bokhari and Nigel A.J. McMillan
DOI: 10.2174/138945012803530161
Published on: 22 August, 2012

Wzy-Dependent Bacterial Capsules as Potential Drug Targets

Volume:13   Issue: 11
Pp: 1421-1431
Daniel J. Ericsson, Alistair Standish, Bostjan Kobe and Renato Morona
DOI: 10.2174/138945012803530279
Published on: 22 August, 2012

Recent Advances in the Development of Thioredoxin Reductase Inhibitors as Anticancer Agents

Volume:13   Issue: 11
Pp: 1432-1444
Yang Liu, Yijing Li, Shenghui Yu and Guisen Zhao
DOI: 10.2174/138945012803530224
Published on: 22 August, 2012

Deleted in Colorectal Cancer (DCC) Pathfinding: Axon Guidance Gene Finally Turned Tumor Suppressor

Volume:13   Issue: 11
Pp: 1445-1453
Molly Duman-Scheel
DOI: 10.2174/138945012803530215
Published on: 22 August, 2012

Co-Morbidity and Self Medication in Schizophrenia: Involvement of Endogenous Morphine Signaling Mechanisms

Volume:13   Issue: 11
Pp: 1454-1457
Richard M. Kream, Hana Kuzelova, Milena Kralickova, Radek Ptacek and George B. Stefano
DOI: 10.2174/138945012803530198
Published on: 22 August, 2012

Recent Approaches to Novel Antibacterials Designed After LPS Structure and Biochemistry

Volume:13   Issue: 11
Pp: 1458-1471
Luca Gabrielli, Alice Capitoli, Davide Bini, Francesca Taraballi, Cristina Lupo, Laura Russo and Laura Cipolla
DOI: 10.2174/138945012803530242
Published on: 22 August, 2012